NF-κB

Cat.No. 产品名称 Information

GC20007 Ginsenoside CK

20(S)-人参皂苷 C-K

A metabolite of ginsenoside Rb1 with diverse biological activity

GN10156 Ginsenoside Rb1

人参皂苷 Rb1; Gypenoside III

A triterpene saponin with diverse biological activities

GN10220 Ginsenoside Rb3

人参皂苷 Rb3; Gypenoside IV

A steroid glycoside with diverse biological activities

GN10549 Ginsenoside Rd

人参皂苷 Rd; Gypenoside VIII

A natural steroid glycoside with diverse effects

GN10307 Ginsenoside Re

人参皂苷 Re; Ginsenoside B2; Panaxoside Re; Sanchinoside Re

A natural steroid glycoside with diverse effects

GN10544 Ginsenoside Rg1

人参皂苷 Rg1; Panaxoside A; Panaxoside Rg1

人参皂苷Rg1是人参的主要活性成分之一，是一种具有多种生物活性的甾体糖苷。人参皂苷Rg1可降低大脑Aβ 水平并减少 NF-κB 核转移。

GN10614 Ginsenoside Rg2

人参皂苷 Rg2; Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2

A natural steroid glycoside with diverse effects

GN10799 Ginsenoside Rg3

20(S)-人参皂苷 Rg3; 20(S)-Propanaxadiol; S-ginsenoside Rg3

A natural steroid glycoside with diverse effects

GC31706 Ginsenoside Rg5

人参皂甙 Rg5

A ginsenoside with diverse biological activities

GN10019 Ginsenoside Rg6

人参皂苷 Rg6

Ginsenoside Rg6 抑制 TNF-α 诱导的 NF-κB 转录活性，在 HepG2 细胞中的 IC50 为 29.34 μM。

GN10584 Ginsenoside Rk1

人参皂苷

人参皂甙 Rk1 是通过在高温下加工人参植物（主要是 Sung Ginseng，SG）而产生的独特成分。

GC31817 Ginsenoside Rk3

人参皂甙 Rk3

GinsenosideRk3存在于Panaxnotoginseng的根中。在HepG2细胞中GinsenosideRk3抑制TNF-α诱导的NF-κB转录活性，IC50值为14.24±1.30μM。

GC17255 Gliotoxin

胶霉毒素,Aspergillin

An immunosuppressive mycotoxin with diverse biological effects

GC60180 Gossypin

棉纤维素

A flavonoid glycoside with diverse biological activities

GC43786 GS-143

4-(3-苄基-4-((5-(2-氟苯基)呋喃-2-基)亚甲基)-5-氧代-4,5-二氢-1H-吡唑-1-基)苯甲酸

An inhibitor of IκBα ubiquitylation

GC91768 GSK205 (hydrobromide) GSK205 is an inhibitor of transient receptor potential vanilloid 4 (TRPV4) and transient receptor potential ankyrin 1 (TRPA1; IC50s = 4.19 and 5.56 µM, respectively, for the rat channels).

GC41218 Guaiacol Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin.

GC69216 HE 3286

NE-3107

HE 3286 是天然抗炎类固醇 β-AET 的合成衍生物。HE 3286 是具有口服活性的 NF-κB 部分抑制剂。HE 3286 降低了促炎信号，包括 IL-6 和基质金属肽酶 3。HE 3286 可自由穿过小鼠血脑屏障。HE 3286 可用于溃疡性结肠炎、关节炎、实验性自身免疫性脑脊髓炎的研究。

GC43810 Helenalin

心菊内酯

An anti-inflammatory sesquiterpene lactone

GC60897 Hesperidin methylchalcone

甲基橙皮甙查尔酮

Hesperidin methylchalcone is the Citrus original products with powerful antioxidant activity.

GC31692 Homoplantaginin

高车前苷

A flavonoid glycoside with antioxidant and anti-inflammatory activities

GC36301 IKKγ NBD Inhibitory Peptide IKKγ NBD Inhibitory Peptide是 NEMO 结合域的多肽，对应着 NEMO 氨基端α螺旋区，可以阻断 TNFα 诱导的 NF-kB 激活。

GC16368 Indole-3-carbinol

3-吲哚甲醇; I3C; 3-Indolemethanol

A natural phytochemical

GC33861 Inulicin (1-O-Acetylbritannilactone)

旋覆花内酯,1-O-Acetylbritannilactone

A sesquiterpene lactone with diverse biological activities

GC39109 Isodeoxyelephantopin

异去氧苦地胆苦素

Isodeoxyelephantopin 是一种倍半萜烯内酯，可从Elephantopus scaber 中分离得到。Isodeoxyelephantopin 可诱导活性氧的生成，抑制NF-κB 的激活。Isodeoxyelephantopin 还能调节LncRNA 的表达，有抗乳腺癌的作用。

GC39095 Isoliquiritin apioside

芹糖异甘草苷

Isoliquiritin apioside (ISLA, ILA), a component isolated from Glycyrrhizae radix rhizome (GR), significantly decreases PMA-induced increases in matrix metalloproteinase (MMP) activities and suppresses PMA-induced activation of mitogen-activated protein kinase (MAPK) and NF-κB. Isoliquiritin apioside possesses anti-metastatic and anti-angiogenic abilities in malignant cancer cells and ECs, with no cytotoxicity.

GC41273 Isoquercetin

槲皮素-3-葡萄糖苷; Quercetin 3-glucoside

A flavonoid with diverse biological activities

GN10804 Isovitexin

异牡荆黄素38953-85-4

A C-glycosylated flavone with diverse biological activities

GC33844 Isovitexin (Saponaretin)

异牡荆黄素; Saponaretin; Homovitexin

A C-glycosylated flavone with diverse biological activities

GC11438 JSH-23

4-甲基-N1-(3-苯基丙基)-1,2-苯二胺

JSH-23 对核转位和 NF-κB 转录活性具有抑制作用，在脂多糖 (LPS) 刺激的巨噬细胞中 IC50 值为 7.1 μM RAW 264.7 。

GC39093 Kamebakaurin Kamebakaurin 是一种从传统中药植物 Isodon excia 中分离出来的贝壳杉烷二萜类化合物。

GC44085 L-Sulforaphene

莱菔素

A natural isothiocyanate

GC10474 Laquinimod (ABR-215062)

拉喹莫德; ABR-215062

An immunomodulator

GC36446 Licochalcone D

甘草查尔酮 D

Licochalcone D (Lico D, LCD, LD), a flavonoid isolated from a Chinese medicinal plant Glycyrrhiza inflata, has antioxidant, anti-inflammatory and anti-cancer properties. Licochalcone D inhibit phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone D inhibits JAK2, EGFR and Met (c-Met) activities and induces ROS-dependent apoptosis. Licochalcone D also induces caspases activation and poly (ADP-ribose) polymerase (PARP) cleavage.

GC36456 Licoricidin

甘草西定

Licoricidin (LCD) 从甘草 Glycyrrhiza uralensis Fisch 中分离，具有抗癌活性。Licoricidin (LCD) 通过诱导周期停滞，诱导细胞凋亡 (apoptosis) 和自噬 (autophagy)，是一种对抗结直肠癌的潜在化学预防或化学治疗剂。Licoricidin (LCD) 通过抑制肿瘤血管生成和淋巴管生成以及肿瘤组织局部微环境的变化抑制肺转移。Licoricidin (LCD) 通过体外和体内 Akt 和 NF-κB 途径的失活，增强吉西他滨诱导的骨肉瘤 (OS) 细胞的细胞毒性。Licoricidin (LCD) 通过 ROS 清除阻断 UVA 诱导的光老化，限制 MMP-1 的活性，被认为是新的局部应用的抗衰老制剂中的活性成分。

GC17608 Lidocaine

利多卡因; Lignocaine

An Analytical Reference Standard

GC33831 Lidocaine hydrochloride (Lignocaine hydrochloride)

盐酸利多卡因; Lignocaine hydrochloride

An Analytical Reference Standard

GC61021 Malachite green oxalate

孔雀石绿草酸盐

Malachite green (Aniline green, Basic green 4, Diamond green B, Victoria green B) is a synthetic dyestuff and antimicrobial with potential carcinogenicity.