NF-κB

NF-κB is a family of conserved and ubiquitous transcription factors that involved in various biological processes including immunity, inflammation, cell growth, differentiation and apoptosis. It is associated with cancer, chronic inflammation and arthritis etc.

Products for NF-κB

Cat.No. 产品名称 Information
GC50139 SP 100030 SP 100030 是一种有效的 NF-κB 和 activator protein-1 (AP-1) 双抑制剂（IC50s 分别为 50 和 50 nM）。
GC37686 Stachydrine
水苏碱
A pyrrolidine betaine with anticancer and cardioprotective effects
GC13840 Stachydrine (hydrochloride)
盐酸水苏碱
A pyrrolidine betaine with anticancer and cardioprotective effects
GC49844 Stercobilin (hydrochloride)
(–)-Stercobilin, L-Stercobilin

A fecal pigment and metabolite of bilirubin
GC11819 Strontium Ranelate
雷尼酸锶; Distrontium renelate; S12911
An antiosteoporotic agent
GC38984 Suberosin
软木花椒素
A prenylated coumarin with diverse biological activities
GC16868 Sulfasalazine
柳氮磺吡啶; NSC 667219
A prodrug form of 5-aminosalicylic acid
GC32737 TAK-243 (MLN7243)
MLN7243
A UAE inhibitor
GC60352 Taraxerol
蒲公英萜醇
Taraxerol 具有抗炎和抗癌作用。
GC34171 Tectochrysin (Techtochrysin)
柚木柯因,Techtochrysin; NSC 80687
A flavonoid with diverse biological activities
GC41573 Theaflavin 3,3'-digallate
茶黄素-3,3'-双没食子酸; TF-3; ZP10
Theaflavin 3,3'-digallate（茶黄素-3,3'-双没食子酸; TF-3; ZP10）是一种有效的寨卡病毒（ZIKV）蛋白酶抑制剂，IC₅₀值为2.3μM。
GC31647 Tomatidine
番茄碱
A steroidal alkaloid with diverse biological activities
GC45064 Tomatidine (hydrochloride)
盐酸番茄碱
A steroidal alkaloid with diverse biological activities
GC38868 TRAF-STOP inhibitor 6877002 TRAF-STOP inhibitor 6877002是一种抑制CD40-TRAF6相互作用的选择性抑制剂（TRAF-STOPs）。
GC48202 Treprostinil (diethanolamine salt)
曲前列尼尔二乙醇胺盐,UT-15C
An agonist of IP₂, DP₂, and EP₂ receptors
GC32041 Triphala
三果宝
Triphala是阿育吠陀的多草药配方，Triphala由三种草本植物Terminaliachebula，Terminaliabellerica，和Phyllanthusemblica组成。Triphala抑制NF-κB活化。Triphala发挥抗真菌(antifungal)作用。具有抗脂肪形成，抗炎，抗肿瘤效果。
GC14402 Triptolide
雷公藤甲素; PG490
雷公藤甲素(Triptolide)是一种二萜三环氧化物,首次从药用植物雷公藤 (Tripterygium wilfordii) 中分离出来,具有免疫抑制,抗炎,抗增殖和抗肿瘤作用。
GN10337 Tyrosol
酪醇
A phenol with diverse biological activities
GC38679 Urolithin B
尿石素B
A metabolite of ellagic acid
GC39564 Vamorolone
地塞米松EP杂质E,VBP15
Vamorolone (VBP15) 是首创的，具有口服活性的解离性类固醇 (dissociative steroidal) 抗炎药和膜稳定剂。Vamorolone 改善肌营养不良，无副作用。Vamorolone 抑制 (NF-κB) 抑制作用，并降低了激素的影响。
GC13429 Vanillic acid
香草酸
香草酸是一种存在于可食用植物和水果中的调味剂，也存在于当归中。
GC52180 WAY-169916 A pathway-selective estrogen receptor ligand
GC31798 WAY-204688 (SIM-688)
SIM-688
WAY-204688 (SIM-688) 是一种雌激素受体 (ER-α) 选择性、口服活性的 NF-κB 转录活性抑制剂，IC50 为 122±30 nM 作用于 NF-κB-荧光素酶κB-luc) 在 HAECT-1 细胞中。
GC17309 Withaferin A
醉茄素A
A steroidal lactone with diverse biological activities
GC31809 Yangonin
甲氧醉椒素
A kavalactone with affinity for the CB₁ receptor
GN10119 Zingerone
姜酮; Vanillylacetone; Gingerone
A phenolic ketone with diverse biological activities