PGE synthase(PGE合酶)

Prostagladin E synthase catalzyes the oxidoreduction of PGHS (prostaglandin endoperoxde h2) into PGE2(prostaglandin E2). It is implicated in physiological conditions such as fever, pain and arthritis etc.

Products for PGE synthase

Cat.No. 产品名称 Information
GC15058 Benzydamine HCl
盐酸苄达明
An Analytical Reference Standard
GC17707 Bismuth Subsalicylate
次水杨酸铋; Bismuth oxysalicylate; Bismuth(III) salicylate basic
Bismuth Subsalicylate 是一种有效的、具有口服活性的抗酸剂和止泻剂。
GC40352 Cafestol
咖啡醇
A natural diterpene which increases serum cholesterol
GC18904 CAY10678
mPGES-1 Inhibitor III
A mPGES-1 inhibitor
GC38431 Dehydroevodiamine
脱氢吴茱萸碱
An alkaloid with diverse biological activities
GC38678 Ethyl Caffeate
咖啡酸乙酯
Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
GC16880 Flurbiprofen
氟比洛芬; dl-Flurbiprofen
A non-selective COX inhibitor
GC14633 HPGDS inhibitor 1
6-(3-氟苯基)-N-[1-(2,2,2-三氟乙基)-4-哌啶基]-3-吡啶羧酰胺
An inhibitor H-PGDS
GC36254 HPGDS inhibitor 2 HPGDS inhibitor 2 是一种高效选择性的造血前列腺素 D 合成酶 (H-PGDS) 抑制剂，IC50 值为 9.9 nM。
GC10564 HQL 79
4-(二苯基甲氧基)-1-[3-(2H-四氮唑-5-基)丙基]哌啶
A selective HPGD synthase inhibitor
GC36463 Limaprost
利马前列素; 17α,20-dimethyl-δ2-PGE1; ONO1206; OP1206
A stable, potent analog of PGE₁
GC16607 Mesalamine
5-氨基水杨酸; Mesalamine; 5-ASA; Mesalazine
An NSAID and active metabolite of sulfasalazine, balsalazide, and olsalazine
GC11743 MF63
2-(9-氯-1H-菲并[9,10-D]咪唑-2-基)-1,3-苯二甲腈,MF 63; MF-63
A potent, selective, and orally active mPGES-1 inhibitor
GC36649 mPGES1-IN-3 mPGES1-IN-3 (Compound 17d) 是一种有效的选择性微粒体前列腺素 E2 合成酶-1 (mPGES-1) 抑制剂，抑制 mPGES-1 酶，IC50 为 8 nM，抑制 A549 细胞，IC50 为 16.24 nM。
GC18700 PF-4693627 An orally bioavailable mPGES-1 inhibitor
GC32038 PGS-IN-1 (KME-4)
KME-4
PGS-IN-1 (KME-4) 是一种有效的前列腺素合成酶 (PGS) 抑制剂，IC50 为 0.28 μM;也抑制 5-脂氧合酶，IC50 为 1.05 μM.
GC11670 Pranoprofen
普拉洛芬
An NSAID and COX-1 inhibitor
GC12330 SAR191801 SAR191801 是一种 hPGDS 抑制剂，在荧光偏振试验或 EIA 试验中的 IC50 为 12 nM。
GN10280 Sinensetin
5,6,7,3',4'-五甲氧基黄酮,Pedalitin permethyl ether
An anti-inflammatory flavone
GC14438 Suprofen
舒洛芬; TN-762
A non-selective NSAID
GC50101 TFC 007 An H-PGDS inhibitor
GC70119 Vipoglanstat
BI 1029539; GS-248; OX-MPI
Vipoglanstat (BI 1029539)，甲酰胺，是一种有效的，选择性的，非肽人前列腺素 E 合成酶 1 (mPGES-1) 小分子抑制剂，具有口服活性。Vipoglanstat 也具有抗炎活性。
GC63394 Zaloglanstat
ISC-27864; GRC-27864
Zaloglanstat (ISC-27864) 是 mPGES-1 的抑制剂，可用于哮喘、骨关节炎、类风湿性关节炎、急性或慢性疼痛和神经退行性疾病等的研究。
GC31687 Zomepirac sodium salt (McN-2783-21-98)
佐美酸钠; McN-2783-21-98
Zomepirac sodium salt (McN-2783-21-98) (McN-2783-21-98) 是一种有效的前列腺素生物合成抑制剂。