EAAT2(兴奋性氨基酸转运蛋白2)

Excitatory amino acid transporter 2 (EAAT2) is the major glutamate transporter and functions to remove glutamate from synapses. An increase in EAAT2 protein expression and function may provide a means to prevent insufficient glutamate reuptake and consequently reduce neuronal damage.

The glial glutamate transporter EAAT2 plays a major role in glutamate clearance. EAAT2 can be upregulated by transcriptional or translational activation.EAAT2 is a potential target for the prevention of excitotoxicity.

Products for EAAT2

Cat.No. 产品名称 Information
GC64288 EAAT2 activator 1 EAAT2 activator 1 是兴奋性氨基酸转运蛋白 2 (EAAT2) 的有效激活剂。EAAT2 是主要的谷氨酸转运蛋白，具有从突触中去除谷氨酸的功能。EAAT2 activator 1 以剂量依赖性方式增加 EAAT2 蛋白水平。
GC38524 WAY-213613 hydrochloride WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM for excitatory amino acid transporter subtype 2 (EAAT2).
GC31075 GT 949 A positive allosteric modulator of EEAT2
GC10875 LDN 212320
LDN-0212320; OSU-0212320
An activator of EAAT2
GC13659 WAY 213613
N-[4-(2-溴-4,5-二氟苯氧基)苯基]-L-天冬酰胺
WAY 213613 是一种有效的选择性人 EAAT2 抑制剂。