Monoamine transporter(单胺转运蛋白)

Monoamine transporters are a family of plasma membrane transporter that regulates the reuptake of neurotransmitters into nerve terminals. It divided into DAT (dopamine transporter), NET (norepinephrine transporter) and SERT (serotonin transporter).

Products for Monoamine transporter

Cat.No. 产品名称 Information
GC70443 GZ-793A GZ-793A是一种口服活性和选择性囊泡单胺转运蛋白-2（VMAT2）抑制剂，Ki为0.029µM。
GC69565 Nisoxetine
尼索西汀
Nisoxetine 是一种有效的和选择性的去甲肾上腺素转运蛋白 (NET) 抑制剂，Kd 值为 0.76 nM。Nisoxetine 是一种抗抑郁试剂和局部麻药，它可以阻断电压门控性钠通道。
GC26029 Valbenazine tosylate
NBI-98854
Valbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM).
GC50649 FFN 200 dihydrochloride Selective fluorescent VMAT2 substrate
GC37820 Trans (2,3)-Dihydrotetrabenazine
四苯喹嗪杂质,(2R,3R,11bR)-rel-Dihydrotetrabenazine; (2R,3R,11bR)-rel-DHTBZ
Trans (2,3)-Dihydrotetrabenazine，是抗精神病药物Tetrabenazine的体内代谢物，能够抑制囊泡单胺转运体 2 (VMAT2)。
GC37768 Tetrabenazine Racemate
丁苯那嗪外消旋体; Ro 1-9569 Racemate
Tetrabenazine (Racemate)是一个有选择性和可逆转的VMAT-2抑制剂。
GC36705 NBI-98782
(+)-α-二氢丁苯那嗪; (+)-DTBZ; (+)-α-Dihydrotetrabenazine; (+)-α-DHTBZ

NBI-98782(alpha-dihydrotetrabenazine)是囊泡单胺转运体（VMAT2）抑制剂，Ki为0.97nM。
GC40180 Tetrabenazine-d6
(+)-丁苯那嗪 D6；(+)-丁苯喹嗪 D6；(+)-特苯那嗪 D6；(+)-四苯喹嗪 D6
An internal standard for the quantification of tetrabenazine
GC31060 Radafaxine hydrochloride (GW-353162A)
盐酸安非他酮吗啉代杂质,GW-353162A; BW-306U

An active metabolite of bupropion
GC30994 Vanilpyruvic acid (Vanylpyruvic acid)
4-羟基-3-甲氧基苯基丙酮酸,Vanylpyruvic acid
香草丙酮酸 (Vanylpyruvic acid) 是儿茶酚胺代谢物和香草乳酸的前体。
GC19370 Valbenazine
缬苯那嗪,NBI-98854
An inhibitor of VMAT2
GC13672 Tetrabenazine
(+)-丁苯那嗪; (+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine
丁苯那嗪是美国食品和药物管理局唯一批准的亨廷顿舞蹈病药物，适用于治疗与亨廷顿舞蹈病相关的舞蹈症。
GC14792 Reserpine hydrochloride
利血平盐酸盐
Irreversible inhibitor of VMAT1 and VMAT2
GN10779 Reserpine
利血平
Irreversible inhibitor of VMAT1 and VMAT2