P-gp(P-糖蛋白)

P-gp (P-glycoprotein) is a ATP-binding cassette transproters which overepxressed in multidrug-resistance cancer cells. It functions in pumping drug out of cell and lower intracellular drug concentration.

Products for P-gp

Cat.No. 产品名称 Information
GC25405 Evodine Evodine, a natural product extracted from Evodiae fructus (EF), is a biomarker for quality assessment of EF in the Chinese Pharmacopoeia. Evodine is a potent P-gp inhibitor.
GC10964 Estradiol 17-(β-D-Glucuronide) (sodium salt)
Β雌二醇17-(Β-D-葡萄糖醛酸)钠盐,E217G,β-Estradiol 17-(β-D-Glucuronide),17β-Estradiol 17-(β-D-Glucuronide),17β-Oestradiol 17-(β-D-Glucuronide)
Estradiol 17-(β-D-Glucuronide)是雌二醇(一种主要的女性性激素)经过代谢形成的产物。
GC17065 Estradiol 3-(β-D-Glucuronide) (sodium salt)
E23G,β-Estradiol 3-(β-D-Glucuronide),17β-Estradiol 3-(β-D-Glucuronide),17β-Oestradiol 3-(β-D-Glucuronide)
An isomer of estradiol-(β-D-glucuronide)
GC10391 Hypophyllanthin
(7S,8S,9R)-9-(3,4-二甲氧基苯基)-6,7,8,9-四氢-4-甲氧基-7,8-双(甲氧基甲基)萘并[1,2-D]-1,3-二恶茂,NSC 619044
A P-glycoprotein inhibitor
GC15795 Rhodamine 123 (chloride)
罗丹明123; RH-123; R-22420
Rhodamine 123 (chloride)是一种细胞渗透性阳离子荧光探针，特异性识别线粒体膜电位，最大激发光/发射光为507/529nm。
GC13375 Dofequidar fumarate
MS-209
A quinoline derivative and inhibitor of multidrug resistance
GC16609 LY335979 (Zosuquidar 3HCL)
唑喹达三盐酸盐; RS 33295-198 trihydrochloride; LY-335979 trihydrochloride
A modulator of P-gp
GC16672 Zosuquidar
(2R)-1-{4-[(1AR,6R,10BS)-1,1-二氟-1,1A,6,10B-四氢二苯并[A,E]环丙并[C]环庚烯-6-基]哌嗪-1-基}-3-(喹啉-5-基氧基)丙-2-醇,LY335979;LY 335979;LY-335979
A modulator of P-gp
GC10928 Tariquidar methanesulfonate, hydrate
TARIQUIDAR二甲磺酸盐六水合物,XR 9576;XR-9576;XR9576
A P-glycoprotein inhibitor
GC15570 Tariquidar
N-[2-[[4-[2-(6,7-二甲氧基-3,4-二氢-1H-异喹啉-2-基)乙基]苯基]氨基甲酰基]-4,5-二甲氧基苯基]喹啉-3-甲酰胺,XR9576, XR 9576, XR-9576,Tariquidar
A P-glycoprotein inhibitor