Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

qq在线咨询
Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

TRP Channel(瞬时受体电位离子通道)

TRP (transient receptor potential) channels are a family of cation channels that sense various external and celluar signals such as mechanical stress, temperature, cellular messengers and exogenous chemicals. It is implicated in vascular tone , neurological disorders, kidney diseases, hypomagnesemia and hypocalcemia etc.

Products for  TRP Channel

  1. Cat.No. 产品名称 Information
  2. GC50590 TRPC6-PAM-C20 TRPC6-PAM-C20 是 TRPC6 通道的选择性正变构调节剂 (PAM)。
  3. GC50557 CBA

    CBA

     A TRPM4 inhibitor
  4. GC50475 AM 12

    TRPC5 inhibitor
  5. GC50268 M 084 hydrochloride TRPC4/5 channel blocker; antidepressant and anxiolytic
  6. GC50261 A 425619

    N-5-异喹啉基-N'-[[4-(三氟甲基)苯基]甲基]脲

     Potent TRPV1 antagonist
  7. GC50188 CIM 0216 A TRPM3 channel activator
  8. GC50115 ASP 7663 A TRPA1 agonist
  9. GC50058 AMG 21629 Potent and selective TRPV1 antagonist
  10. GC39198 GSK1702934A A TRPC3 and TRPC6 activator
  11. GC46199 PF-05105679 A TRPM8 antagonist
  12. GC39117 Methyl syringate

    丁香酸甲酯

     Methyl syringate (Syringic Acid Methyl Ester), a plant phenolic compound, is a specific and selective TRPA1 agonist.
  13. GC38726 1,4-Cineole

    1,4-桉叶素

     1,4-Cineole (Isocineole) is a widely distributed, natural, oxygenated monoterpene. 1,4-Cineole, present in eucalyptus oil, activates both human TRPM8 and human TRPA1.
  14. GC34489 BI-749327

    BI-749327是一种可口服利用的TRPC6拮抗剂，
  15. GC45907 RN-9893 (hydrochloride) A TRPV4 antagonist
  16. GC38501 GSK205 GSK205 是一种高效的，选择性的 TRPV4 拮抗剂，IC50 值为 4.19 μM，可抑制 TRPV4 介导的 Ca2+ 内流。
  17. GC38465 GsMTx4 GsMTx4是一种由34个氨基酸组成的蜘蛛毒素肽，属于huwentoxin-1家族。
  18. GC37831 TRPM8 agonist WS-3

    N-乙基-5-甲基-2-(1-甲基乙基)环己甲酰胺

     Cyclohexanecarboxamide (Ethyl menthane carboxamide, WS3, Hexahydrobenzamide) is a cooling agent and an agonist at TRPM8 receptors (EC50 = 3.7 μM).
  19. GC37655 SN 2 SN 2 是一种有效的 TRPML3 离子通道激活剂，EC50 为 1.8±0.13 μM。
  20. GC36627 ML204 hydrochloride A selective TRPC4 channel blocker
  21. GC36609 Mifamurtide

    米伐木肽; MTP-PE; L-MTP-PE; CGP 19835

    Mifamurtide(CGP19835; MTP-PE)可作用于骨肉瘤。
  22. GC36277 Hydroxy-α-sanshool

    羟基-α-山椒素

     Hydroxy-α-sanshool是一种TRPA1和TRPV1激动剂，其EC50值分别为69和1.1µM，常用于高脂血症的研究。
  23. GC35970 EIPA hydrochloride

    L593754 hydrochloride; MH 12-43 hydrochloride

     EIPA hydrochloride (L593754 hydrochloride) 是一种 TRPP3 channel 抑制剂，其 IC50 值为 10.5 μM。EIPA 还抑制 Na+/H+ 交换器 (NHE) 和巨噬细胞。
  24. GC35501 Beta-Eudesmol

    β-桉叶醇

     A sesquiterpene with diverse biological activities
  25. GC35407 Asivatrep

    PAC-14028

     Asivatrep (PAC-14028) 是高效的选择性的瞬时受体电位香草酸亚型1 (TRPV1) 拮抗剂。
  26. GC35316 AMG2850 AMG2850 是一个有效的、有口服活性的TRPM8 的选择性拮抗剂。
  27. GC35222 ABT-239 ABT-239 是一种新颖的，高效的，非咪唑类的 H3R 拮抗剂，也是 TRPV1 的拮抗剂。
  28. GC35010 (Z)-Capsaicin

    (Z)-辣椒素; Zucapsaicin; Civamide; cis-Capsaicin

     Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain. It is also a TRPV-1 modulator.
  29. GC34951 (-)-Menthol

    L-薄荷醇

     A monoterpene with diverse biological activities
  30. GC44816 Resolvin D2

    7(S),16(R),17(S)-Resolvin D2

     A product of the action of 15- and 5-LO on DHA
  31. GC44075 Linopirdine

    利诺吡啶,DuP 996

     A neurotransmitter release enhancer
  32. GC43884 Hyperforin (dicyclohexylammonium salt)

    贯叶金丝桃素二环己基铵盐,Hyp-DCHA, Hyperforin-DCHA

     A natural compound with diverse actions
  33. GC40860 AC1903 A TRPC5 inhibitor
  34. GC40808 (+)-Menthol

    D-薄荷醇,D-Menthol

     A monoterpene alcohol with antifungal activity
  35. GC40696 (R)-(+)-Pulegone

    胡薄荷酮

     A monoterpene with anti-inflammatory activity
  36. GC34833 TC-I 2014 TC-I2014(compound5)是一种强效的、苯并咪唑类的、TRPM8的拮抗剂，其对犬类、人和大鼠通道的IC50值分别为0.8nM,3.0nM和4.4nM。在疼痛动物模型中具有抗痛觉超敏作用。
  37. GC33675 Podocarpic acid

    罗汉松酸

     Podocarpicacid是一种天然产物，为TRPA1的激活剂，具有多种功效。
  38. GC33443 Pyr6

    N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide

     Pyr6 是 TRPC3 的选择性抑制剂，IC50 为 0.49 uM（在 thapsigargin 耗尽的天然 RBL-2H3 细胞中，Ca2+ 流入抑制）。
  39. GC33424 SAR7334 A TRPC6 channel blocker
  40. GC33423 JT010 A TRPA1 channel agonist
  41. GC33158 D-3263 D-3263是一种有效的TRPM8激动剂，具有抗肿瘤活性。
  42. GC32961 D-3263 hydrochloride D-3263hydrochloride是一种可口服的TRPM8激动剂。
  43. GC32849 Pico145 (HC-608)

    HC-608

     Pico145 (HC-608) (HC-608) 是一种显着的 TRPC1/4/5 通道抑制剂，抑制 (-)-englerin A 激活的 TRPC4/TRPC5 通道，在细胞中的 IC50 为 0.349 和 1.3 nM，并且显示没有对 TRPC3、TRPC6、TRPV1、TRPV4、TRPA1、TRPM2、TRPM8 的影响。
  44. GC31953 Camphor ((±)-Camphor)

    樟脑; (±)-Camphor

     Camphor (2-Bornanone, Bornan-2-one, 2-Camphanone, Formosa) is a bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora and used topically as a skin antipruritic and as an anti-infective agent.
  45. GC31236 JYL 1421 (SC 0030)

    SC 0030

     A TRPV1 antagonist
  46. GC30893 TRPM8 Antagonist TRPM8 antagonist 2 (TRPM8 Antagonist) is a potent and selective antagonist of TRPM8 with IC50 of 0.2 nM that can be used for the pharmacological treatment of neuropathic pain syndromes.
  47. GC30837 A-1165442 A-1165442是有效，竞争性，有口服活性的TRPV1拮抗剂，对人TRPV1的IC50值为9nM。
  48. GC30799 HC-070 HC-070是一种瞬时受体电位通道蛋白4/5(TRPC4/TRPC5)拮抗剂，在细胞中，对hTRPC5和hTRPC4的IC50值分别为9.3nM和46nM。
  49. GC30725 TRPV antagonist 1

    TRPVantagonist1是一种有效的瞬时受体电位V型(TRPV)拮抗剂，IC50值<250nM。
  50. GC30546 TRPC6-IN-1 TRPC6-IN-1是TRPC6的一个抑制剂，其EC50值为4.66μM。
  51. GC30096 Pyr10

    Pyr10是一种新型TRPC3选择性抑制剂,作用于转染YFP-TRPC3的HEK293细胞,抑制ROCE,IC50为0.72uM。

Items 51 to 100 of 163 total

per page
  2. 1
  3. 2
  4. 3
  5. 4

Set Descending Direction