TRPV1

TRPV1 (transient receptor potential vanilloid 1) is a calcium permeant cation channel that detects thermal stimuli and noxious chemical. It is a drug target for analgesics.

Products for TRPV1

Cat.No. 产品名称 Information
GC12636 Capsiconiate
Coniferyl (E)-8-methyl-6-nonenoate
A partial agonist of TRPV1
GC16627 Docosahexaenoyl Serotonin Potential TRPV1 antagonist
GC15580 Stearoyl Serotonin Potential TRPV1 antagonist
GC12097 Palmitoyl Serotonin Potential TRPV1 antagonist
GC11147 Oleoyl Serotonin TRPV1 antagonist
GC12772 Eicosapentaenoyl Serotonin A potential TRPV1 antagonist
GC14761 Mavatrep
JNJ-39439335
Mavatrep (JNJ-39439335) 是一种具有口服活性、选择性和有效的 TRPV1 拮抗剂，对 hTRPV1 通道具有高亲和力 (Ki=6.5 nM)。
GC14580 SB705498 SB705498是一种口服生物可利用的、竞争性的辣椒素介导的 TRPV1 受体拮抗剂（人类、大鼠和豚鼠的pKis分别为7.6、7.5和7.3）。SB705498能够快速、可逆地抑制辣椒素、酸或热介导的人类TRPV1激活。
GC13003 AMG-517
N-[4-[[6-[4-(三氟甲基)苯基]-4-嘧啶基]氧基]-2-苯并噻唑基]乙酰胺
A TRPV1 antagonist
GC17918 Capsazepine
辣椒平
Capsazepine是瞬时受体电位香草素1（TRPV1）受体的特异性拮抗剂，IC₅₀值为562 nM。