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Home >> Signaling Pathways >> JAK/STAT Signaling

JAK/STAT Signaling(JAK/STAT 信号通路)

Products for  JAK/STAT Signaling

  1. Cat.No. 产品名称 Information
  2. GC15925 PD 158780

    N4-(3-溴苯基)-N6-甲基-吡啶并[3,4-D]嘧啶-4,6-二胺

     An ErbB receptor family inhibitor
  3. GC13168 AG 825

    酪氨酸磷酸化抑制剂AG825,Tyrphostin AG-825

     An inhibitor of Her2/Neu tyrosine kinase activity
  4. GC11744 AG 555

    Tyrphostin AG 555

     A tyrphostin EGFR inhibitor
  5. GC14494 AG 99

    酪氨酸磷酸化抑制剂A46,(E)-Tyrphostin 46; (E)-Tyrphostin AG 99

     An inhibitor of EGF receptor kinase
  6. GC14854 Colivelin Colivelin (CLN) 是一种脑渗透性神经保护肽，对 Aβ 具有长期有效的作用；神经退行性疾病中的沉积、神经元凋亡和突触可塑性缺陷。
  7. GC12359 Hispidulin

    高车前素; Dinatin

     A flavonoid with diverse biological activities
  8. GC16021 Lavendustin A

    薰草菌素; RG-14355

     A selective inhibitor of EGF receptor-associated tyrosine kinase
  9. GC10889 Artesunate

    青蒿琥酯

     青蒿琥酯（Artesunate）是一种抗疟疾化合物，是信号转导及转录激活蛋白3（STAT-3）和膜谷胱甘肽S-转移酶（EXP1）的抑制剂。
  10. GC18126 Balsalazide

    巴柳氮

     A prodrug form of 5-ASA
  11. GC15901 Niclosamide monohydrate

    氯硝柳胺一水合物; BAY2353 monohydrate

     An anthelmintic mitochondrial uncoupler
  12. GC15271 Tyrphostin AG 879

    AG 879

     A non-specific tyrphostin ErbB2 inhibitor
  13. GC14170 Nifuroxazide

    硝呋齐特

     A nitrofuran antibiotic
  14. GC13586 Niclosamide

    氯硝柳胺; BAY2353

     An anthelmintic mitochondrial uncoupler
  15. GC10250 Mubritinib (TAK 165)

    木利替尼; TAK-165

     A selective inhibitor of HER2
  16. GC13854 AG-490 (Tyrphostin B42)

    酪氨酸磷酸化抑制剂AG490

     AG-490 (Tyrphostin B42)是EGFR抑制剂,IC50为0.1 µM, AG-490对JAK2也有抑制作用。
  17. GC12579 GLPG0634

    非戈替尼,GLPG0634

     A JAK1 inhibitor
  18. GC16698 AZD-9291 mesylate

    奥希替尼甲磺酸盐; AZD-9291 mesylate; Mereletinib mesylate

    An inhibitor of mutant EGFR
  19. GC16308 AZD-9291

    奥希替尼; AZD-9291; Mereletinib

    An inhibitor of mutant EGFR
  20. GC17982 Icotinib

    埃克替尼; BPI-2009

     An EGFR inhibitor
  21. GC11126 Mutant EGFR inhibitor

    N-[5-[[5-氯-4-(1H-吲哚-3-基)-2-嘧啶基]氨基]-2-[[2-(二甲基氨基)乙基]甲基氨基]-4-甲氧基苯基]-2-丙烯酰胺

     Mutant EGFR inhibitor 是从专利WO 2013014448 A1中提取的一种有效的选择性突变EGFR抑制剂；抑制 EGFRL858R、EGFRExon 19 缺失和 EGFRT790M。
  22. GC15669 AST-1306 TsOH

    艾力替尼; AST-1306 (TsOH)

     An irreversible inhibitor of EGFR, HER2, and HER4
  23. GC17530 OSI-420

    OSI-420; CP-373420 hydrochloride

     OSI-420 (OSI-420) 是厄洛替尼的活性代谢物。厄洛替尼是一种有效的 EGFR 酪氨酸激酶抑制剂。
  24. GC14676 Pacritinib (SB1518)

    帕克替尼

     An equipotent inhibitor of FLT3 and JAK2
  25. GC11264 CNX-2006 An irreversible inhibitor of mutant EGFRs
  26. GC16000 WHI-P180

    3-[(6,7-二甲氧基-4-喹唑啉基)氨基]苯酚,Janex 3

     A multi-kinase inhibitor
  27. GC11172 TAK-285 A dual inhibitor of EGFR and HER2
  28. GC13761 AZD8931 (Sapitinib)

    沙普替尼; AZD-8931

     A reversible inhibitor of ErbB1/EGFR, ErbB2/HER2, and ErbB3/HER3
  29. GC11691 AST-1306

    AST1306; AST 1306

     An irreversible inhibitor of EGFR, HER2, and HER4
  30. GC12478 ARRY-380

    ARRY380; ARRY 380

     An inhibitor of EGFR
  31. GC12249 Varlitinib (ARRY334543)

    泛EGFR小分子抑制剂(VARLITINIB),ARRY-334543; ARRY 334543

     An inhibitor of EGFR and HER2
  32. GC17226 AG-1478

    Tyrphostin AG-1478; AG 1478; NSC 693255; AG1478

     An inhibitor of EGF receptor kinase
  33. GC14653 NSC 74859

    S3I-201;NSC74859;NSC-74859;S3I 201,

     A STAT3 inhibitor
  34. GC10362 Neratinib (HKI-272)

    来那替尼; HKI-272

     A dual inhibitor of EGFR and HER2
  35. GC10225 Dacomitinib (PF299804, PF299)

    达克替尼; PF-00299804; PF-299804

     A pan-ErbB receptor tyrosine kinase inhibitor
  36. GC15134 Fludarabine Phosphate (Fludara)

    磷酸氟达拉滨; NSC 118218 phosphate

     A prodrug form of fludarabine and 2-fluoro-ara-ATP
  37. GC17283 AP26113

    Brigatinib analog

     A potent ALK inhibitor
  38. GC10944 Butein

    紫铆因; 2’,3,4,4’-tetrahydroxy Chalcone

     A plant polyphenol
  39. GC17647 AG-18

    酪氨酸磷酸化抑制剂23,Tyrphostin A23; RG-50810; AG 18

     An inhibitor of EGF receptor kinase
  40. GC17886 Stattic

    STAT3 Inhibitor V

     Stattic是第一个非肽类小分子STAT3抑制剂，能有效抑制STAT3的激活和核转位。
  41. GC11015 PD168393 An irreversible EGFR kinase inhibitor
  42. GC11892 AEE788 (NVP-AEE788)

    6-[4-[(4-乙基-1-哌嗪)甲基]苯基]-N-[(1R)-1-苯基乙基]-7H-吡咯并[2,3-D]嘧啶-4-胺,NVP-AEE 788

     An inhibitor of EGFR and VEGFR tyrosine kinases
  43. GC14144 Fludarabine

    氟达拉滨; F-ara-A; NSC 118218

     Fludarabine是一种抑制DNA合成的嘌呤类似物。
  44. GC12910 Canertinib (CI-1033)

    卡奈替尼; CI-1033; PD-183805

     Canertinib (CI-1033) (CI-1033;PD-183805) 是一种有效且不可逆的 EGFR 抑制剂；抑制细胞 EGFR 和 ErbB2 自磷酸化，IC50 为 7.4 和 9 nM。
  45. GC13257 AC480 (BMS-599626)

    AC480

     A dual inhibitor of EGFR and HER2
  46. GC11250 WZ8040 An inhibitor of mutant EGFR
  47. GC17473 Pelitinib (EKB-569)

    培利替尼; EKB-569; WAY-EKB 569

     An EGFR receptor tyrosine kinase inhibitor
  48. GC13091 CP-724714

    2-甲氧基-N-[(2E)-3-[4-[[3-甲基-4-[(6-甲基-3-吡啶基)氧基]苯基]氨基]-6-喹唑啉基]-2-丙烯-1-基]乙酰胺

     A selective HER2/ErbB2 tyrosine kinase inhibitor
  49. GC15494 WZ4002 A potent inhibitor of EGFR-T790M kinase activity
  50. GC14102 Genistein

    染料木素; NPI 031L

     染料木黄酮是一种异黄酮，属于类黄酮化合物，存在于多种植物中。
  51. GC17621 TPCA-1

    5-(4-氟苯基)-2-脲基噻吩-3-甲酰胺

     A selective inhibitor of IKK2

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