MAPK Signaling(MAPK信号通路)
Products for MAPK Signaling
- ERK(90)
- MEK1/2(64)
- NKCC(6)
- MNK(10)
- PKA(53)
- p38(100)
- Rac(2)
- Raf(68)
- RasGAP (Ras- P21)(1)
- JNK(60)
- cAMP(35)
- Protein Kinase G(2)
- RSK(32)
- Other(4)
- MAPKAPK(1)
- MKK(2)
- KLF(3)
- MAP3K(20)
- MAP4K(25)
- MAPKAPK2 (MK2)(9)
- Mixed Lineage Kinase(10)
- Cat.No. 产品名称 Information
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GC12882
AS 602801
本塔马莫,Bentamapimod;AS602801;AS-602801
A selective, orally bioavailable JNK inhibitor
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GC13508
Trametinib (GSK1120212)
曲美替尼; GSK1120212; JTP-74057
Trametinib (GSK1120212, JTP-74057) 是第二代 MEK 激酶小分子抑制剂。
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GC14732
PLX-4720
N-[3-[(5-氯-1H-吡咯并[2,3-B]吡啶-3-基)羰基]-2,4-二氟苯基]-1-丙磺酰胺,PLX4720, PLX-4720, PLX 4720
An orally-available inhibitor of the B-raf mutant B-RafV600E
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GC10397
PD0325901
N-[(2R)-2,3-二羟基丙氧基]-3,4-二氟-2-[(2-氟-4-碘苯)氨基]苯甲酰胺,PD0325901,PD-0325901,PD 0325901,PD325901,PD 325901,PD-325901
PD0325901是一种具口服活性、选择性和非ATP竞争性的丝裂原活化蛋白激酶激酶（MEK）抑制剂，IC50值为0.33nM。
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GC17369
Sorafenib
索拉非尼; Bay 43-9006
索拉非尼Sorafenib是Raf-1和B-Raf的多激酶抑制剂，IC50分别为6 nM和22 nM;Sorafenib对VEGFR-2 VEGFR-3 PDGFR-β Flt-3和c-KIT也有抑制作用，IC50值分别为90 nM、20 nM、57 nM、59 nM和68 nM;索拉非尼能诱导自噬细胞凋亡和激活铁死亡，并具有抗肿瘤活性。
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GC13412
Vemurafenib (PLX4032, RG7204)
维罗非尼; PLX4032; RG7204; RO5185426
An inhibitor of mutant V600E and wild type B-Raf
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GN10267
Loureirin B
龙血素 B
A flavonoid with diverse biological activities
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GN10063
Arctigenin
牛蒡子苷元; (-)-Arctigenin
Arctigenin是一种天然木脂素化合物，已证实具有抗癌活性。Arctigenin具有强效的抗氧化、抗炎和抗病毒（甲型流感病毒）活性。
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GN10804
Isovitexin
异牡荆黄素38953-85-4
A C-glycosylated flavone with diverse biological activities
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GN10590
Bakuchiol
补骨脂酚; (S)-(+)-Bakuchiol
A natural meroterpene with retinol-like effects
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GN10784
Rhoifolin
野漆树苷
A flavonoid glycoside with diverse biological activities
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GN10016
Carnosol
鼠尾草酚
A phenol with diverse biological activities
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GN10752
Pachymic acid
茯苓酸; 3-O-Acetyltumulosic acid
A triterpenoid with diverse biological activities
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GN10481
Corynoxeine
去氢钩藤碱
An alkaloid with diverse biological activities
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GN10409
cor-nuside
山茱萸新苷
A bisiridoid glycoside with diverse biological activities
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GN10709
Polyphyllin A
重楼皂苷I
A steroid saponin with anticancer activity
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GN10248
Hesperitin
橙皮素
A hypocholesterolemic citrus flavonoid
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GN10814
Quercitrin
槲皮苷; Quercetin 3-rhamnoside
A flavonoid glycoside
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GN10494
Astragaloside IV
黄芪皂苷 IV
Astragaloside IV是黄芪中提取的一种有效成分，可减轻心肌缺血/再灌注损伤，抑制HAdV-3复制，减少HAdV-3诱导的细胞凋亡 。
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GN10664
Honokiol
和厚朴酚; NSC 293100
和厚朴酚（Honokiol）是一种具有多种生物活性天然双酚类化学物质，靶向多种信号分子，具有有效的抗氧化、抗炎、抗血管生成和抗癌等活性，还具有广谱抗菌和抗人类免疫缺陷病毒（HIV）活性。
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GN10307
Ginsenoside Re
人参皂苷 Re; Ginsenoside B2; Panaxoside Re; Sanchinoside Re
A natural steroid glycoside with diverse effects
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GN10336
Daphnetin
瑞香素; 7,8-Dihydroxycoumarin
A coumarin derivative with diverse biological activities
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GN10023
Isorhamnetin
异鼠李素; 3'-Methylquercetin
A natural flavonol aglycone
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GC15299
Staurosporine(CGP 41251)
星形孢菌素; Antibiotic AM-2282; STS; AM-2282
Staurosporin 是一种小激酶抑制剂，是一种从细菌 Streptomyces staurosporeus 中提取的生物碱。
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GP10075
PKA inhibitor fragment (6-22) amide
蛋白酶A抑制剂6-22酰胺,Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile
A synthetic peptide inhibitor of PKA
