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Home >> Signaling Pathways >> MAPK Signaling >> p38

p38

p38 (p38 mitogen-activated protein kinases) are serine/threonine kinases that activated by environmental stress and proinflammatory cydtokines. They mediates cell growth, differentiation, transcrption and development.

Products for  p38

  1. Cat.No. 产品名称 Information
  2. GC31988 p38α inhibitor 1

    p38αinhibitor1是p38α的抑制剂，来自专利WO2008076265A1。
  3. GC31924 AZD7624 AZD7624是一种可吸入的p38抑制剂，具有高效的抗炎活性。
  4. GC31697 Dilmapimod (SB-681323)

    度马莫得; SB-681323; GW 681323

     Dilmapimod (SB-681323,GW 681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease.
  5. GC31058 FR 167653 free base FR-167653是一种选择性的p38MAPK抑制剂。
  6. GC30676 MAPK13-IN-1 MPAK13-IN-1是MAPK13(p38δ)的一个抑制剂，其IC50值为620nM。
  7. GC30646 Skatole(3-Methylindole)

    粪臭素; 3-Methylindole; 3-Methyl-1H-indole

     Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.
  8. GC30609 p38 MAPK-IN-2 p38MAPK-IN-2是一种p38kinase的抑制剂。
  9. GC30158 p38-α MAPK-IN-1

    p38-α MAPK-IN-1 is an inhibitor of p38-α, with IC50 value of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.
  10. GC19366 UM-164

    DAS-DFGO-II

     An inhibitor of Src and p38 MAPK kinases
  11. GC19325 SD 0006

    3-[N-(2-羟基乙酰基)-4-哌啶基]-4-(4-嘧啶基)-5-(4-氯苯基)吡唑,SD-06

     An inhibitor of p38α MAPK
  12. GC19304 R1487 Hydrochloride An inhibitor of p38α MAPK
  13. GC19019 Acumapimod

    BCT197

     An inhibitor of p38α MAPK
  14. GC18602 p38 MAPK Inhibitor IV

    2,2'-磺酰基双(3,4,6-三氯苯酚),p38 MAP Kinase Inhibitor IV

     An inhibitor of p38 MAP kinases
  15. GC18273 SB 202190 (hydrochloride) A potent and selective p38 MAP kinase inhibitor
  16. GC14982 SD 169

    1H-吲哚-5-甲酰胺,5-Carbamoylindole

     A selective inhibitor of p38α and p38β MAP kinase
  17. GC13142 RWJ 67657

    4-(4-氟苯基)-2-(4-羟基-1-丁炔)-1-(3-苯基丙基)-5-(4-吡啶基)咪唑,JNJ-3026582

     An orally active inhibitor of p38α and p38β
  18. GC10593 BMS-582949 hydrochloride A p38α MAP kinase inhibitor
  19. GC16019 SB 202474 A negative control for SB 202190 and SB 203580
  20. GC15814 Pamapimod (R-1503, Ro4402257)

    Ro4402257; R1503

     An orally bioavailable inhibitor of p38α MAP kinase
  21. GC16997 BMS-582949 A p38α MAP kinase inhibitor
  22. GC11857 Pexmetinib (ARRY-614)

    ARRY-614

     A dual inhibitor of Tie2 and p38 MAPK
  23. GC11922 SB 706504 p38 MAPK inhibitor
  24. GC11635 TA 02 An inducer of cardiomyocyte differentiation
  25. GC13825 TA 01 An inducer of cardiomyocyte differentiation
  26. GC12646 AL 8697 AL 8697 是一种具有口服活性的特异性 p38α MAPK 抑制剂，IC50 为 6 nM。
  27. GC15477 DBM 1285 dihydrochloride p38 MAPK inhibitor
  28. GC17957 SX 011 p38α inhibitor
  29. GC10403 EO 1428

    EO 1428, p38 MAP Kinase Inhibitor VIII, p38 Mitogen-activated Protein Kinase Inhibitor VIII

     An inhibitor of p38α and p38β MAP kinases
  30. GC13116 JX 401

    p38 MAPK Inhibitor VI, p38 Mitogen-activated Protein Kinase Inhibitor VI

     A potent, reversible inhibitor of p38α MAPK
  31. GC11180 CMPD-1

    CMPD 1

     A substrate-selective p38α MAPK inhibitor
  32. GC17725 SKF 86002 dihydrochloride An anti-inflammatory agent
  33. GC14645 PF-3644022 PF-3644022 是一种有效的、选择性的、具有口服活性和 ATP 竞争性的 MAPKAPK2 (MK2) 抑制剂，IC50 为 5.2 nM，Ki 为 3 nM。
  34. GC14899 AMG 548 An inhibitor of p38α MAPK
  35. GC13717 Losmapimod

    洛批莫德; GSK-AHAB; GW856553X; SB856553

     A dual p38α and p38β MAPK inhibitor
  36. GC13001 SB 203580 hydrochloride

    SB 203580 hydrochloride; RWJ 64809 hydrochloride

     A water soluble p38 MAPK inhibitor
  37. GC17737 PD 169316

    4-[4-(4-氟苯基)-2-(4-硝基苯基)-1H-咪唑-5-基]吡啶

     A specific p38 MAPK inhibitor
  38. GC16543 TAK-715

    N-(4-(2-乙基-4-(3-甲基苯基)噻唑-5-基)吡啶-2-基)苯甲酰胺

     An inhibitor of p38α MAPK
  39. GC17508 VX-702

    6-[(氨基羰基)(2,6-二氟苯基)氨基]-2-(2,4-二氟苯基)-3-吡啶甲酰胺

     An inhibitor of p38 MAP kinases
  40. GC12926 VX-745

    VX-745

     A p38α MAPK inhibitor
  41. GC10261 PH-797804

    PH797804;PH 797804

     A selective p38 MAPK inhibitor
  42. GC11497 BIRB 796 (Doramapimod)

    达马莫德; BIRB 796

     A potent inhibitor of p38 MAPK
  43. GC16835 LY2228820

    5-[2-(叔丁基)-4-(4-氟苯基)-1H-咪唑-5-基]-3-(2,2-二甲基丙基)-3H-咪唑并[4,5-B]吡啶-2-胺甲磺酸盐,LY2228820 dimesylate

     A potent inhibitor of p38α MAP kinase
  44. GC13968 SB202190 (FHPI)

    4-(4-氟苯基)-2-(4-羟基苯基)-5-(4-吡啶基)-1H-咪唑

     SB 202190是一种选择性p38 MAP激酶抑制剂,对p38α和p38β2的IC50分别为50 nM和100 nM。
  45. GC13595 SB 203580

    4-(4-氟苯基)-2-(4-甲基亚磺酰基苯基)-5-(4-吡啶基)-1H-咪唑,SB 203580; RWJ 64809

     SB 203580是p38-MAPK（有丝分裂原活化蛋白激酶）通路的特异性抑制剂。
  46. GC13578 Skepinone-L

    Skepinone L

     An inhibitor of p38 MAPK
  47. GC10054 SB 239063

    反式-1-(4-羟基环己基)-4-(4-氟苯基)-5-(2-甲氧基嘧啶-4-基)咪唑,SB-239063;SB239063

     A selective p38 MAPK inhibitor
  48. GN10590 Bakuchiol

    补骨脂酚; (S)-(+)-Bakuchiol

     A natural meroterpene with retinol-like effects
  49. GN10784 Rhoifolin

    野漆树苷

     A flavonoid glycoside with diverse biological activities
  50. GN10409 cor-nuside

    山茱萸新苷

     A bisiridoid glycoside with diverse biological activities
  51. GN10248 Hesperitin

    橙皮素

     A hypocholesterolemic citrus flavonoid

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