Metabolism(代谢)

Cat.No. 产品名称 Information

GC91791 Cholic Acid 3-sulfate (potassium salt)

3-Sulfocholate,3-Sulfocholic Acid

Cholic acid 3-sulfate is a metabolite of the primary bile acid cholic acid .

GC91783 FA16 FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.

GC91775 h-e5'NT Inhibitor 5C

Human Ecto-5'-nucleotidase Inhibitor 5C

h-e5'NT Inhibitor 5C is an inhibitor of ecto-5'-nucleotidase, also known as CD73 (IC50s = 0.37 and 1.66 µM for the human and rat enzymes, respectively).

GC91773 18-hydroxy Oleoyl Leucine-d7 18-hydroxy Oleoyl leucine-d7 is intended for use as an internal standard for the quantification of 18-hydroxy oleoyl leucine by GC- or LC-MS.

GC91768 GSK205 (hydrobromide) GSK205 is an inhibitor of transient receptor potential vanilloid 4 (TRPV4) and transient receptor potential ankyrin 1 (TRPA1; IC50s = 4.19 and 5.56 µM, respectively, for the rat channels).

GC91767 ENPP3 Inhibitor 5J ENPP3 inhibitor 5J is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) and ENPP3 (IC50s = 0.59 and 0.62 µM, respectively, for the human enzymes).

GC91761 ABBV-CLS-484 (hydrochloride)

Osunprotafib

ABBV-CLS-484 is a dual inhibitor of protein tyrosine phosphatase 1N (PTP1N) and PTP2N (IC50s = 2.5 and 1.8 nM, respectively).

GC91705 Etomidate-d5

(+)-Etomidate-d5,d-Etomidate-d5,(R)-Etomidate-d5

Etomidate-d5 is intended for use as an internal standard for the quantification of etomidate by GC- or LC-MS.

GC91691 viFSP1

Versatile Inhibitor of Ferroptosis Suppressor Protein 1,Versatile Inhibitor of FSP1

viFSP1 is a species-independent inhibitor of ferroptosis suppressor protein 1 (FSP1; IC50s = 34 and 83 nM for the human and mouse enzymes, respectively).

GC91690 TASP0277308 TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).

GC91667 NSC 44625

Bendroflumethiazide Impurity A,2,4-Disulfamyl-5-trifluoromethylaniline

NSC 44625 is an inhibitor of carbonic anhydrase II (CAII; Ki = 63 nM for the human enzyme).

GC91641 4-Hydroxy-1-(2-phenylethyl)piperidine 4-Hydroxy-1-(2-phenylethyl)piperidine is a building block that has been used in the synthesis of ligands of the muscarinic acetylcholine receptor (mAChR) or sigma non-opioid intracellular receptor 1 (σ1 receptor).

GC91623 Ferroptosis Inducer 24 Ferroptosis inducer 24 is an inducer of ferroptosis.

GC91613 FerroLOXIN-1 FerroLOXIN-1 is an inhibitor of the 15-lipoxygenase-2 (15-LO-2) and phosphatidylethanolamine-binding protein 1 (PEBP1) catalytic complex.

GC91598 GPX4 16

Glutathione Peroxidase 4 16

GPX4 16 is an inhibitor of glutathione peroxidase 4 (GPX4).

GC91548 Rosuvastatin EP Impurity A (calcium salt) Rosuvastatin EP impurity A is a potential impurity in commercial preparations of the HMG-CoA reductase inhibitor rosuvastatin.

GC91547 Tanzawaic Acid B

(+)-Tanzawaic Acid B

Tanzawaic acid B is a fungal metabolite that has been found in Penicillium and has diverse biological activities.

GC91543 (E/Z)-Droloxifene

3-Hydroxytamoxifen

(E/Z)-Droloxifene is a mixture of (E)-droloxifene, a selective estrogen receptor modulator (SERM), and (Z)-droloxifene.

GC91499 Voriconazole-d3 N-oxide Voriconazole-d3 N-oxide is intended for use as an internal standard for the quantification of voriconazole N-oxide by GC- or LC-MS.