Metabolism(代谢)

Cat.No. 产品名称 Information

GC52404 γ-Glu-Phe (trifluoroacetate salt)

γ-Glutamylphenylalanine

A dipeptide with metabolism-altering activity

GC52400 γ-Glu-Ala (trifluoroacetate salt)

γ-Glutamylalanine, γ-L-Glutamyl-L-alanine

A dipeptide

GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate)

Neuropeptide Q, NPQ, NWTPQAMLYLKGAQ-NH2, SPX1

An endogenous peptide and agonist of GAL₂ and GAL₃

GC52384 NFAT Inhibitor (cell-permeable) (trifluoroacetate salt)

Nuclear Factor Activated T cells Inhibitor, RRRRRRRRRRRGGGMAGPHPVIVITGPHEE, 11R-VIVIT

A cell-permeable form of NFAT inhibitor

GC52376 BMP2-derived Peptide (trifluoroacetate salt)

Bone Morphogenic Protein 2-derived Peptide, KIPKASSVPTELSAISTLYL-NH2

A synthetic peptide

GC52361 AMARA Peptide (trifluoroacetate salt)

AMARAASAAALARRR-OH, H-Ala-Met-Ala-Arg-Ala-Ala-Ser-Ala-Ala-Ala-Leu-Ala-Arg-Arg-Arg-OH

A peptide substrate for AMPK

GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide

Citrullinated Enolase-1-biotin, α-Enolase Peptide (Citrulline Residues 8 + 14)

A biotinylated and citrullinated α-enolase peptide

GC52329 Betamethasone-d5

β-Methasone-d5, SCH 4831-d5

An internal standard for the quantification of betamethasone

GC52324 3-(3-Hydroxyphenyl)propionic Acid sulfate

3-HPPA sulfate

A metabolite of certain phenols and glycosides

GC52323 L-Isoleucine-13C6

L-(+)-Isoleucine-13C6

An internal standard for the quantification of L-isoleucine

GC52318 Oleic Acid-13C5

9Z-Octadecenoic Acid-13C5, C18:1(9Z)-13C5, cis-9-Octadecenoic Acid-13C5

An internal standard for the quantification of oleic acid

GC52317 BCP-T.A. A ferroptosis inducer

GC52315 GK241 An sPLA₂ (Type IIA) inhibitor

GC52304 Perfluoroheptanoic Acid

PFHpA

A perfluoroalkyl substance

GC52290 (R)-HTS-3 An inhibitor of LPCAT3

GC52278 Creatine Phosphate (sodium salt hydrate)

Phosphocreatine

A phosphorylated form of creatine

GC52257 Perfluorohexanoic Acid

Perfluorocaproic Acid, PFHxA, Undecafluorocaproic Acid, Undecafluorohexanoic Acid

A perfluoroalkyl substance

GC52253 α-Enolase (1-19)-biotin Peptide

Enolase-1 (1-19)-biotin

A biotinylated α-enolase peptide

GC52251 Imidacloprid Impurity 1 A potential impurity in commercial preparations of imidacloprid

GC52231 Heptadecanoyl-L-carnitine-d3 (chloride)

CAR 17:0-d3, C17:0 Carnitine-d3, L-Carnitine heptadecanoyl ester-d3, L-Heptadecanoylcarnitine-d3

An internal standard for the quantification of heptadecanoyl-L-carnitine

GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone

(±)-δ-(3,4-Dihydroxyphenyl)-γ-Valerolactone, 5-(3',4'-Dihydroxyphenyl)-γ-VL

An active metabolite of various polyphenols

GC52219 Heptadecanoyl-L-carnitine (chloride)

CAR 17:0, C17:0 Carnitine, L-Carnitine heptadecanoyl ester, L-Heptadecanoylcarnitine

A long-chain acylcarnitine

GC52214 Nicotinamide riboside-d4 (triflate) An internal standard for the quantification of nicotinamide riboside

GC20109 Cefotiam hexetil hydrochloride

盐酸头孢替安酯; CTM-HE hydrochloride; SCE-2174 hydrochloride

Cefotiam hexetil hydrochloride 是可口服的第三代头孢菌素，是 cefotiam 的前药，但无抗菌作用。Cefotiam 是一种抗生素。

GC20095 5,7-Dihydroxy-4-methylcoumarin

NSC 5302

A synthetic coumarin with diverse biological activities

GC20091 α-Arbutin

α-熊果苷; 4-Hydroxyphenyl α-D-glucopyranoside

A glycosylated hydroquinone with diverse biological activities

GC67661 S-2E S-2E 是一种具有口服活性且非竞争性的 HMG-CoA 还原酶和乙酰-CoA 羧化酶 (acetyl-CoA carboxylase) 抑制剂。S-2E 具有抗高血脂作用，可用于家族性高胆固醇血症和混合性高脂血症的研究。

GC67211 BAPTA tetrapotassium

BAPTA四钾盐

An extracellular calcium chelator

GC66645 L-Adenosine

L-腺苷

L-Adenosine 是一种代谢稳定的对映异构体类似物，也是一种潜在的探针。L-Adenosine 具有弱抑制性腺苷脱氨酶 (ADA) 活性，Ki 值为 385 μM。L-Adenosine 可用于腺苷摄取和积累的研究。

GC66450 sEH inhibitor-7 sEH inhibitor-7 (compound c-2) 是一种可溶性环氧化物水解酶 (sEH) 抑制剂，IC50 分别为 0.15 μM (mouse sEH)和6.2 μM (human sEH)。可溶性环氧化物水解酶 (sEH) 在调节血压和炎症的内源性化学介质的代谢中起着重要作用。

GC66360 Girentuximab

G250; cG250

Girentuximab (G250) 是一种嵌合单克隆抗体，可与碳酸酐酶 IX (CAIX) 结合，碳酸酐酶 IX 是一种在透明细胞肾细胞癌 (ccRCC) 中广泛表达的细胞表面糖蛋白。

GC66197 α-?Terpinyl acetate Terpinyl Acetate (alpha-Terpinyl), a naturally occuring compound found in several essential oils, is a flavouring agent.

GC66059 YZ129 YZ129 是 HSP90-磷酸酶-NFAT 通路的抑制剂，可抗胶质母细胞瘤，直接与热休克蛋白 (HSP90) 结合，对NFAT核易位的 IC50 值为820 nM。YZ129 在 G2/M 期诱导GBM细胞周期阻滞，促进细胞凋亡，抑制肿瘤细胞增值和迁移。

GC66042 Enpp-1-IN-14 ENPP1-IN-2 是一种有效的外核苷酸焦磷酸酶/磷酸二酯酶 (ENPP1) 抑制剂，对重组人 ENPP-1 的 IC50 为 32.38 nM。ENPP1-IN-2 具有抗肿瘤活性。

GC66029 hCAI/II-IN-6 hCAI/II-IN-6 是一种具有口服活性的 human carbonic anhydrase (CA) 抑制剂。hCAI/II-IN-6 选择性地抑制 hCA II 和 hCA VII，对 hCA I，hCA II，hCA VII 和 hCA XII 的 Ki 值分别为 220，4.9，6.5 和＞50000 nM。hCAI/II-IN-6 在体内显示抗惊厥活性和抗最大电击 (MES) 活性。hCAI/II-IN-6 可以用于癫痫的研究。

GC66015 IHVR-11029 IHVR-11029 是ER α-glucosidases 的抑制剂，其 EC50 值为0.09 μM。

GC66005 CVT-11127

GS-456332

CVT-11127 (FMK13918) is an inhibitor of stearoylCoA desaturase-1 (SCD1). CVT-11127 reduces lipid synthesis and impaires proliferation by blocking the progression of cell cycle through the G(1)/S boundary and by triggering programmed cell death.