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Home >> Signaling Pathways >> Metabolism >> Ferroptosis

Ferroptosis(铁死亡)

Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.

Products for  Ferroptosis

  1. Cat.No. 产品名称 Information
  2. GC61895 Ammonium iron(III) citrate

    柠檬酸铁 (III) 铵; Ammonium ferric citrate; FAC

     Ammonium ferric citrate (Ferric ammonium citrate, Ammonium iron(III) citrate, Iron ammonium citrate, FerriSeltz) induces ferroptosis in non-small-cell lung carcinoma through the inhibition of GPX4-GSS/GSR-GGT axis activity.
  3. GC61436 Gallic acid hydrate

    没食子酸-水合物; 3,4,5-Trihydroxybenzoic acid hydrate

     A phenol with diverse biological activities
  4. GC19706 Propacetamol hydrochloride

    盐酸丙帕他莫

     A prodrug form of acetaminophen
  5. GC48954 CP21 An iron chelator
  6. GC48650 DTUN A lipophilic hyponitrite radical initiator
  7. GC48059 Rosiglitazone-d3

    罗格列酮 d3

     An internal standard for the quantification of rosiglitazone
  8. GC48030 RC574

    An inhibitor of ferroptosis
  9. GC48029 RC363 An inhibitor of ferroptosis
  10. GC47870 Pantothenate Kinase Inhibitor

    3-(2,4-二甲基吡啶并[2',3':3,4]吡唑并[1,5-A]嘧啶-3-基)-N-(3-(甲硫基)苯基)丙酰胺

     A reversible inhibitor of pantothenate kinase
  11. GC47478 JKE-1716 A GPX4 inhibitor
  12. GC47477 JKE-1674 A GPX4 inhibitor and active metabolite of ML-210
  13. GC47123 Coumarin-Quinone Conjugate A fluorescent substrate for NADH:ubiquinone oxidoreductases
  14. GC47065 CAY10773 A derivative of sorafenib
  15. GC46352 (S)-DO271 An inactive control for DO264
  16. GC61187 Pioglitazone D4

    匹格列酮-D4,U 72107-d4

     An internal standard for the quantification of pioglitazone
  17. GC50345 Liproxstatin-1 hydrochloride A ferroptosis inhibitor
  18. GC45995 DO264 An ABHD12 inhibitor
  19. GC45928 iFSP1

    iFSP1是一种有效的不依赖谷胱甘肽的铁死亡抑制蛋白1（FSP1）抑制剂，其EC50值为103nM。
  20. GC45820 Balsalazide-d4 Balsalazide-d4 是氘标记的 Balsalazide。
  21. GC45793 IM-93 A dual inhibitor of ferroptosis and NETosis
  22. GC45792 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)

    Iron Salophene Complex, N,N'-o-Phenylenebis(salicylideneaminato)iron(III) Chloride

     An inducer of ferroptosis
  23. GC45764 Ciclopirox-d11 (sodium salt)

    HOE 296b-d11

     A neuropeptide with diverse biological activities
  24. GC38429 Dihydroartemisinic acid

    双氢青蒿酸; Dihydroqinghao acid

     A precursor to artemisinin
  25. GC37665 Sorafenib (D4)

    Bay 43-9006-d4

     Sorafenib D4 (Bay 43-9006 D4) 是 Sorafenib 氘代化合物标准品。Sorafenib 是一种多激酶抑制剂，抑制 Raf-1，B-Raf 和 VEGFR-3 的 IC50 分别为6 nM，20 nM，22 nM。
  26. GC37664 Sorafenib (D3)

    索拉非尼-D3,Bay 43-9006-d3; Donafenib

     An internal standard for the quantification of sorafenib
  27. GC36926 Piperazine Erastin A ferroptosis inducer
  28. GC36011 Ethylenediaminetetraacetic acid trisodium salt

    依地酸三钠盐; EDTA trisodium salt; Trisodium EDTA

     Ethylenediaminetetraacetic acid (EDTA) is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity.
  29. GC35876 DL-Glutamine

    DL-谷氨酰胺; (±)-Glutamine; DL-Gl

     DL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes.
  30. GC35795 D,L-Buthionine-(S,R)-sulfoximine hydrochloride

    Buthionine sulfoximine hydrochloride; BSO hydrochloride

     A γ-glutamylcysteine synthetase inhibitor
  31. GC35692 Chrysosplenetin

    猫眼草黄素

     A flavonoid with diverse biological activities
  32. GC35399 Artefenomel

    OZ439

     An antimalarial agent
  33. GC35398 Arteannuin B

    青蒿素B

     A precursor to artemisinin with diverse biological activities
  34. GC34980 (E)-Ferulic acid

    反式阿魏酸,(E)-Coniferic acid

     Trans-ferulic acid is a potent activator of AMPKunder high glucose condition.
  35. GC45248 (-)-FINO2 A ferroptosis inducer
  36. GC44947 SRS16-86 A ferroptosis inhibitor
  37. GC44893 Siramesine (fumarate)

    Lu 28-179

     A selective σ2 receptor agonist
  38. GC44851 Rosiglitazone (potassium salt)

    罗格列酮钾盐,BRL 49653 potassium

     A PPARγ agonist
  39. GC44214 ML-162 A GPX4 inhibitor
  40. GC43623 Erastin2

    35MEW28

     Erastin2 是一种有效的系统 xc 抑制剂和铁死亡诱导剂。
  41. GC43329 Cu-ATSM

    copper-ATSM, CuII(atsm)

     A copper-containing compound with diverse biological activities
  42. GC43297 Coenzyme Q2

    辅酶Q2

     A biosynthetic precursor to CoQ10 and an inhibitor of mitochondrial complex I
  43. GC43231 Cerivastatin (sodium salt)

    西立伐他汀钠

     An inhibitor of HMG-CoA reductase
  44. GC42928 BHT

    2,6-二叔丁基对甲酚

     A synthetic antioxidant
  45. GC42042 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE

    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine, 15(S)-HpETE-SAPE, 15(S)-hydroperoxyeicostetraenoic acid-SAPE

    An oxidized phospholipid
  46. GC42041 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC

    15(S)-HpETE-SAPC, 15(S)-Hydroperoxyeicostetraenoic Acid-SAPC, 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Phosphatidylcholine

    An oxidized phospholipid
  47. GC42040 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE

    15(S)-HETE-SAPE, 15(S)-Hydroxyeicosatetraenoic Acid-SAPE, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine

    An oxidized phospholipid
  48. GC42039 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC

    15(S)-HETE-SAPC, 15(S)-Hydroxyeicostetraenoic Acid-SAPC, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylcholine

     An oxidized phospholipid
  49. GC41293 Glutathione ethyl ester

    GSH-EE, GSH ethyl ester, GSH monoethyl ester

     A cell-permeable derivative of glutathione
  50. GC40922 SRS11-92

    AA9

     A ferroptosis inhibitor
  51. GC34939 UAMC-3203 hydrochloride A ferroptosis inhibitor

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