5-Lipoxygenase(5-脂氧合酶)

5-lipoxygenase catalyzes oxidation of AA at the 5-position to yield 5-HpETE and is a current target for pharmaceutical intervention in a number of diseases such as asthma, atherosclerosis and several cancers.

Products for 5-Lipoxygenase

Cat.No. 产品名称 Information
GC16046 Piriprost (potassium salt)
U-60257B
A novel 5-lipoxygenase inhibitor
GC14601 BW 755C Dual 5-LO/COX inhibitor
GC12159 HZ52 A reversible inhibitor of 5-lipoxygenase
GC13379 1-Naphthyl 3,5-dinitrobenzoate
1-(3,5-Dinitrobenzoyloxy)naphthalene,1-Naphthalonol 3,5-dinitrobenzoate
A dual inhibitor of 5-LO and mPGES-1
GC10331 Ebselen
依布硒; SPI-1005; PZ-51; CCG-39161
A peroxynitrite scavenger
GC10821 11-keto-β-Boswellic Acid
11-酮基-BETA-乳香酸,11-oxo-β-Boswellic acid,KBA
A 5-LO inhibitor
GC14282 3-acetyl-11-keto-β-Boswellic Acid
11-羰基-Β-乙酰乳香酸,3-O-acetyl-11-keto-β-Boswellic acid,AKBA
A selective 5-LO inhibitor
GC10451 U-73122
1-[6-[((17Β)-3-雌酮-1,3,5[10]-三烯-17-基)氨基]乙基]-1H-吡咯-2,5-二酮
U-73122是有效的、选择性的磷脂酶C（PLC）抑制剂，IC₅₀值约为1-2.1µM，也可抑制5-脂氧合酶（5-LO）。
GC14435 Zileuton sodium
齐留通钠盐; A 64077 sodium; Abbott 64077 sodium
A reversible inhibitor of 5-lipoxygenase
GC16014 Zileuton
齐留通; A 64077; Abbott 64077
A reversible inhibitor of 5-lipoxygenase
GC14751 Malotilate
马洛替酯; NKK 105
A hepatoprotective agent