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Home >> Signaling Pathways >> Metabolism >> Phospholipase

Phospholipase(磷脂酶)

Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.

Products for  Phospholipase

  1. Cat.No. 产品名称 Information
  2. GC44549 Palmitoyl thio-PC A chromogenic substrate for PLA2
  3. GC44223 ML-299

    CID 56593087

     Dual inhibitor of PLD1 and PLD2
  4. GC44222 ML-298 A selective inhibitor of PLD2
  5. GC43815 Heptanoyl thio-PC A thioester phospholipase substrate
  6. GC43812 HEPC

    2Hexadecanoylthio1Ethylphosphorylcholine

     A thioester phospholipase substrate
  7. GC43756 GK187 A GVIA iPLA2 inhibitor
  8. GC43701 FTY720 phenoxy-biotin Biotin-tagged FTY720 analog
  9. GC43695 Folipastatin

    磷脂他汀

     An inhibitor of PLA2
  10. GC43671 FKGK 18 An inhibitor of GVIA iPLA2
  11. GC43670 FKGK 11 A selective iPLA2 inhibitor
  12. GC43305 Compound 48/80 (hydrochloride)

    C48/80 trihydrochloride

     复合物48/80三盐酸盐是N-甲基-p-甲氧基苯乙胺与甲醛缩合产物的混合物。
  13. GC43179 CAY10590

    GK115

     A potent and selective sPLA2 inhibitor
  14. GC43161 CAY10502 A potent inhibitor of cPLA2α
  15. GC42885 AX 048 A cPLA2 inhibitor
  16. GC42855 ARN19874 An inhibitor of NAPE-PLD
  17. GC42843 Arachidonoyl thio-PC

    2-deoxy-2-thio Arachidonoyl PC

     A PLA2 substrate
  18. GC42611 7-hydroxycoumarinyl-γ-Linolenate

    UmbelliferylγLinolenate

     A fluorogenic substrate
  19. GC42029 1-Palmitoyl-2-linoleoyl PE

    1-Palmitoyl-2-Linoleoyl PE, PLPE, (1Palmitoyl, 2Linoleoyl)Phosphatidylethanolamine, (1Palmitoyl, 2Linoleoyl)Phosphoethanolamine

     A product of lipid biosynthesis
  20. GC41808 1,2-Dioctanoyl PC

    3-二(辛酰氧基)丙基2-(三甲基铵基)乙基磷酸酯

     A short chain analog of phosphatidylcholine
  21. GC41782 1,2-bis(heptanoylthio) Glycerophosphocholine

    Diheptanoyl ThioPC, 1,2bis(Heptanoylthio)1,2dideoxysnglycero3phosphorylcholine

     A substrate for PLA2s
  22. GC41004 Rhamnetin

    鼠李素

     A flavonoid with diverse biological activities
  23. GC40794 Sphinganine (d18:0)

    D-赤式-C18-二氢-D-神经鞘氨醇

     Sphingolipid pathway intermediate
  24. GC40679 (S)-Bromoenol lactone

    (S)-BEL; (S,E)-Bromoenol lactone

     A selective iPLA2β inhibitor
  25. GC40678 (R)-Bromoenol lactone

    (R,E)-Bromoenol lactone

     A selective iPLA2γ inhibitor
  26. GC40545 cis-Parinaric Acid

    α-Parinaric Acid

     A naturally-occurring PUFA
  27. GC33457 1-Naphthaleneacetic acid (1-Naphthylacetic acid)

    1-萘乙酸; 1-Naphthylacetic acid

     1-Naphthaleneacetic acid (α-Naphthaleneacetic acid) is a synthetic plant hormone in the auxin family.
  28. GC32768 Quinacrine dihydrochloride (Mepacrine dihydrochloride) Quinacrine是一种荧光探针，使胆碱能受体蛋白发生构象转变，低μM水平对AML细胞具有作用活性，平均IC50为2.30μM。
  29. GC32224 Lp-PLA2 -IN-1 Lp-PLA2-IN-1可以抑制beta-lactamase-IN-1的活性，例如动脉粥样硬化,阿尔茨海默氏症。
  30. GC31825 Varespladib methyl (A-002)

    A-002; LY333013

     Varespladibmethyl (A-002) (A-002; LY333013) 是 II 组分泌型磷脂酶 A2 (PLA2) 的选择性抑制剂。
  31. GC31355 AA26-9

    AA26-9, KK007-N1

     A pan-serine hydrolase inhibitor
  32. GC30610 LY 178002

    LY178002是一种有效的5-lipoxygenase，phospholipaseA2抑制剂，对5-lipoxygenase的IC50值为0.6μM，能够抑制人多形核白细胞产生LTB4，同时可相对较弱地抑制cyclooxygenase的活性。
  33. GC30561 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 2-(E-2-decenoylamino)ethyl2-(cyclohexylethyl)sulfide是一种由压力诱发的溃疡和低毒性抑制剂，可以在压力引起的溃疡大鼠中，维持磷脂酶A2(phospholipaseA2)和前列腺素E2(prostaglandinE2)的含量水平。
  34. GC30464 Ecopladib (PLA 725)

    PLA 725

     Ecopladib (PLA 725) 是细胞溶质磷脂酶 A2α 的亚微摩尔抑制剂； (cPLA2α)，在 GLU 胶束和大鼠全血试验中，IC50 分别为 0.15 μM 和 0.11 μM。
  35. GC30180 ST271 ST271 is a tyrphostin-like protein tyrosine kinase (PTK) inhibitor which inhibits phospholipase D (PLD) activity.
  36. GC11055 10-Pyrene-PC

    1-Palmitoyl-2-pyrenedecanoyl Phosphatidylcholine

     A substrate for some PLA2s
  37. GC19186 GW4869 GW4869是一种非竞争性中性鞘脂酶抑制剂，IC50为1微摩尔。
  38. GC18691 CAY10594 CAY10594 是一种有效的磷脂酶 D2 (PLD2) 抑制剂（体外 IC50 为 140 nm，细胞内为 110 nm）。
  39. GC18559 Lysophosphatidylethanolamines (egg)

    溶血磷脂酰乙醇胺(鸡蛋)

     A mixture of lysophosphatidylethanolamines isolated from egg
  40. GC18305 CAY10650 Potent cPLA2α inhibitor
  41. GC11520 ST638

    Α-氰基-(3-乙氧基-4-羟基-5-苯基硫代甲基)肉桂酰胺

     Tyrosine kinase inhibitor
  42. GC14521 ONO-RS-082 A PLA2 inhibitor
  43. GC10645 MJ33 (lithium salt)

    An inhibitor of the PLA2 activity of Prdx6
  44. GC18141 EA4 An inhibitor of PLA2 from red blood cells
  45. GC11116 Thioetheramide-PC

    1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine

     A competitive, reversible inhibitor of sPLA2
  46. GC11243 Halopemide

    卤培米特,NSC 354856,R34301

     Inhibitor of phospholipase D1 and D2
  47. GC13276 Oleyloxyethyl Phosphorylcholine

    磷酰胆碱

    A PLA2 inhibitor
  48. GC16770 Arachidonic Acid Leelamide A novel fatty acid amide
  49. GC13351 VU0359595

    CID-53361951,ML-270

     A selective PLD1 inhibitor
  50. GC11021 Bromoenol lactone

    (6E)-Bromoenol lactone

     A selective, potent, irreversible inhibitor of iPLA2
  51. GC10565 7-hydroxycoumarinyl Arachidonate

    Umbelliferyl Arachidonate

    A substrate for cPLA2

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