Phospholipase(磷脂酶)

Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.

Products for Phospholipase

Cat.No. 产品名称 Information
GC13930 N-(p-amylcinnamoyl) Anthranilic Acid
2-(3-(4-戊基苯基)丙烯酰胺基)苯甲酸,ACA
A TRP channel blocker and PLA₂ inhibitor
GC17889 ML 349 A selective and reversible inhibitor of LYPLA2
GC18039 ML 348
GNF-Pf-1127
A selective LYPLA1 inhibitor
GC10162 JJKK 048 JJKK 048 是一种超强效和高选择性的单酰基甘油脂肪酶 (MAGL) 抑制剂。
GC11073 ML 298 hydrochloride A selective inhibitor of PLD₂
GC13948 GPi 688 GPi 688 是一种有效且具有口服活性的糖原磷酸化酶 (GPa) 抑制剂，对人肝 GPa、大鼠肝 GPa 和人骨骼肌 GPa 的 IC50 分别为 19 nM、61 nM 和 12 nM。
GC15877 CP 316819
GPi 819
An inhibitor of glycogen phosphorylase A
GC17684 VU 0364739 hydrochloride phospholipase D2 (PLD2) inhibitor
GC13620 FIPI
5-Fluoro-2-indolyl deschlorohalopemide
Potent inhibitor of PLD₁ and PLD₂
GC15888 VU 0155069
CAY10593
Selective inhibitor of phospholipase D₁
GC16115 AACOCF3
花生四烯基三氟甲酮,ATK, AATFMK

An inhibitor of cPLA₂ and iPLA₂
GC17420 OBAA OBAA 是一种有效的磷脂酶 A2 (PLA2) 抑制剂，IC50 为 70 nM。
GC16364 LY 311727 An inhibitor of Group IIA sPLA₂
GC16687 Edelfosine
1-O-十八烷基-2-O-甲基-SN-甘油-3-磷酸,2-O-methyl PAF C-18
Edelfosine ((R)-ET-18-OCH3) 是一种醚脂质类似物，具有抗 HIV 和抗肿瘤活性。
GC13585 YM 26734 A group IIA sPLA₂ inhibitor
GC14090 o-3M3FBS An inactive analog of m-3M3FBS
GC16286 m-3M3FBS
2,4,6-三甲基-N-[3-(三氟甲基)苯基]苯磺酰胺
An activator of phospholipase C
GC16714 PACOCF3
1,1,1-三氟-2-十七烷酮,Palmityltrifluoromet?hylketone
Antagonizes DP receptor agonist effects
GC12420 MAFP
Methyl Arachidonyl Fluorophosphonate
An inhibitor of MAGL, FAAH, cPLA₂, and iPLA₂
GC11631 Melittin
蜂毒肽
蜂毒肽是一种 PLA2 活化剂，可刺激低分子量 PLA2 的活性，而不会增加高分子量 PLA2 的活性。
GC17960 U 73343 An inactive analog of U-73122
GC12411 RHC 80267
1,6-双(环己基脒基羰基氨基)己烷,U-57908
An inhibitor of DAGL
GC10451 U-73122
1-[6-[((17Β)-3-雌酮-1,3,5[10]-三烯-17-基)氨基]乙基]-1H-吡咯-2,5-二酮
U-73122是有效的、选择性的磷脂酶C（PLC）抑制剂，IC₅₀值约为1-2.1µM，也可抑制5-脂氧合酶（5-LO）。
GC12880 GSK 2830371 An inhibitor of Wip1 phosphatase
GC16418 CP-91149
5-氯-N-[(1S,2R)-3-(二甲基氨基)-2-羟基-3-氧代-1-(苯基甲基)丙基]-1H-吲哚-2-甲酰胺
A glycogen phosphorylase inhibitor
GC12361 Darapladib
N-[2-(二乙氨基)乙基]-N-[4'-(三氟甲基)-1,1'-联苯-4-甲基]-2-[2-(4-氟苄硫基)-4-氧代-4,5,6,7-四氢-1H-环戊并[D]嘧啶-1-基]乙酰胺,SB-480848;SB480848;SB 480848
A reversible inhibitor of Lp-PLA₂
GC17851 D609
D609钾盐,D-609 potassium, D 609, D-609
A competitive inhibitor of PC-specific PLC
GC17203 Varespladib (LY315920)
伐瑞拉迪; LY315920
Inhibitor of group IIA, IIE, and X forms of sPLA₂
GN10683 Tanshinone I
丹参酮I,Tanshinone A
A diterpene with diverse biological activities