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Home >> Signaling Pathways >> Obesity, Appetite Control & Diabetes

Obesity, Appetite Control & Diabetes(肥胖，食欲控制 & 糖尿病)

Obesity, Appetite Control & Diabetes

Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more

Products for  Obesity, Appetite Control & Diabetes

  1. Cat.No. 产品名称 Information
  2. GC91544 Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

    Fmoc-Lys(tBuOCO-(CH2)16-CO-Glu(AEEA-AEEA)-OtBu)-OH

     Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide .
  3. GC91493 Semaglutide Side Chain Semaglutide side chain is a synthetic intermediate.
  4. GC72222 Survodutide Survodutide（BI 456906）是一种强效的选择性胰高血糖素受体/GLP-1受体（GCGR/GLP-1R）双重激动剂，在CHO-K1细胞中的EC50分别为0.52 nM和0.33 nM。
  5. GC72096 Bamadutide Bamadutide（SAR425899）是一种强效的双胰高血糖素样肽-1受体/胰高血糖激素受体激动剂。
  6. GC70855 LSN3318839 LSN3318839是一种口服有效的胰高血糖素样肽-1受体(GLP-1R)的阳性变构调节剂。
  7. GC91480 Exendin-4 (3-39) amide (trifluoroacetate salt)

    Exendin (3-39)

     Exendin-4 (3-39)酰胺是一种糖肽样肽1受体（GLP-1R）激动剂，也是exendin-4 (48-86)酰胺的活性代谢物。
  8. GC91449 Ipamorelin (acetate)

    Aib-His-D-2-Nal-D-Phe-Lys-NH2; NNC 26-0161

     Ipamorelin是一种五肽生长激素分泌素（GHS）和GHS受体1a（GHS-R1a）激动剂。
  9. GC26233 Docosahexaenoic Acid-d5

    C22:6 n-3-d5 C22:6(4Z,7Z,10Z,13Z,16Z,19Z)-d5 Cervonic Acid-d5 DHA-d5 4,7,10,13,16,19-Docosahexaenoic Acid-d5

    Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-MS.
  10. GC91123 C18 Ganglioside GM3-d3 (d18:1/18:0-d3) (ammonium salt, synthetic)

    C18 GM3-d3, N-ω-CD3-Octadecanoyl monosialoganglioside GM3, Monosialoganglioside GM3-d3, N-Stearoyl Monosialoganglioside GM3-d3

    一种用于量化神经节苷脂GM3的内部标准。
  11. GC91083 Tiopronin-Cysteine Disulfide

    α-Mercaptopropionylglycine-Cysteine Disulfide

    一种硫普罗宁的代谢产物。
  12. GC91042 Tauro-Obeticholic Acid (sodium salt)

    Obeticholic Acid Taurine Conjugate, Tauro-OCA, Tauro-6-Ethyl-CDCA, Tauro-6-Ethylchenodeoxycholic Acid, T-ECDCA

    一种欧贝替胆酸的活性代谢物。
  13. GC91037 ZLY28

    一种FXR激动剂和FABP1抑制剂。
  14. GC90949 Adenosine-5'-O-(3-thiotriphosphate) (sodium salt)

    Adenosine 5'-(γ-thio)-triphosphate, ATPγS

    一种P2Y11受体激动剂。
  15. GC90819 2,3,7,8-Tetrachlorodibenzofuran

    PCDF 83, 2,3,7,8-TCDF, TCDF

    一种多氯二苯并呋喃和二恶英
  16. GC90698 Eicosapentaenoic Acid-d5 ethyl ester

    EPA-d5 ethyl ester

    一种用于量化乙酰化二十碳五烯酸乙酯的内部标准。
  17. GC90582 Perfluorooctanesulfonic Acid

    Heptadecafluorooctanesulfonic Acid, Perfluorooctane sulfonate, Perfluorooctylsulfonic Acid, PFOS

    一种全氟烷基物质
  18. GC90496 β-Cortolone

    20β-Cortolone, NSC 56997

    一种皮质醇的代谢产物。
  19. GC90363 10(11)-Cl-BBQ

    一种作为AhR激动剂的混合物。
  20. GC90312 1-Palmitoyl-d9-2,3-Dipalmitoyl-sn-glycerol

    Glycerol Tripalmitate-d9, TG(16:0-d9/16:0/16:0), Tripalmitin-d9, 1,2,3-Tripalmitoyl-sn-glycerol-d9, Tripalmitoylglycerol-d9

    一种用于量化1,2,3-三棕榈酰-rac-甘油的内部标准。
  21. GC69439 Mazdutide

    IBI-362; LY-3305677; OXM-3

     Mazdutide (IBI-362; LY-3305677) 是一种长效合成胃泌酸调节素类似物。Mazdutide 也是胰高血糖素样肽 (GLP-1R) 与胰高血糖素受体 (GCGR) 的共激动剂。Mazdutide 具有安全性和耐受性，可用于肥胖和 2 型糖尿病 (T2D) 的研究。
  22. GC20142 Beta-Sitosterol (purity>98%)

    β-谷甾醇 (purity>98%); β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%))
  23. GC20130 2-NBG-1

    NBDGlucose
  24. GC52507 Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)

    Hypocretin 1, OXA

     A hypothalamic neuropeptide
  25. GC52506 Ghrelin (human) (trifluoroacetate salt)

    Lenomorelin

     A growth hormone releasing peptide
  26. GC52504 Human Vitamin D Receptor Reporter Assay System

    NR1I1, VDR

     A nuclear receptor cell-based reporter assay
  27. GC52502 Peptide YY (3-36) (trifluoroacetate salt)

    Pancreatic Peptide YY, Peptide Tyrosine Tyrosine

     A satiety hormone
  28. GC52497 Lactosylceramide (porcine RBC)

    LacCer

     A sphingolipid
  29. GC52496 Sulfatide (bovine) (sodium salt)

    Galactosylceramide I3-sulfate, Ganglioside SM4, I3SO3-GalCer, SM4, Sulfated Galactocerebroside, 3-O-Sulfogalactosylceramide

     A mixture of isolated bovine sulfatides
  30. GC52493 Glucosylceramide (bovine buttermilk)

    GluCers (buttermilk), Glucocerebrosides (buttermilk)

     A sphingolipid
  31. GC52490 Glucagon (hydrochloride) A peptide hormone
  32. GC52476 Bax Inhibitor Peptide V5 (trifluoroacetate salt)

    BIP V5, VPMLK

     A Bax inhibitor
  33. GC52453 Orexin A (17-33) (human, mouse, rat, bovine) (trifluoroacetate salt)

    OXA (17-33)

     A peptide orexin receptor 1 agonist
  34. GC52428 10-oxo-12(Z)-Octadecenoic Acid-d5

    10-keto-12Z-Octadecenoic Acid-d5, 10-oxo-12-cis-Octadecenoic Acid-d5

     An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid
  35. GC52398 10-oxo-12(Z)-Octadecenoic Acid ethyl ester

    10-keto-12Z-Octadecenoic Acid ethyl ester, 10-oxo-12-cis-Octadecenoic Acid ethyl ester

     An ester form of 10-oxo-12(Z)-octadecenoic acid
  36. GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate)

    Neuropeptide Q, NPQ, NWTPQAMLYLKGAQ-NH2, SPX1

     An endogenous peptide and agonist of GAL2 and GAL3
  37. GC52388 [D-Lys3]-GHRP-6 (trifluoroacetate salt)

    D-Lys3-Growth Hormone Releasing Peptide 6, His-D-Trp-D-Lys-Trp-D-Phe-Lys-NH2

     An antagonist of GHS-R1a
  38. GC52380 AOD-9604 (acetate) A synthetic lipolytic peptide
  39. GC52331 Lactoyl Phenylalanine

    Lac-Phe, N-Lactoyl-Phenylalanine

    A secondary metabolite
  40. GC52323 L-Isoleucine-13C6

    L-(+)-Isoleucine-13C6

     An internal standard for the quantification of L-isoleucine
  41. GC52283 L-Cysteine-15N-d3

    L-Cys-15N-d3, L-(+)-Cysteine-15N-d3, (R)-Cysteine-15N-d3

     An internal standard for the quantification of L-cysteine
  42. GC52251 Imidacloprid Impurity 1 A potential impurity in commercial preparations of imidacloprid
  43. GC52214 Nicotinamide riboside-d4 (triflate) An internal standard for the quantification of nicotinamide riboside
  44. GC20027 (±)5(6)-DiHET MaxSpec® Standard

    (±)5,6-DiHETrE

     A racemic version of a CYP450 pathway metabolite of arachidonic acid
  45. GC52135 Tesofensine

    特索芬辛,NS-2330

     A triple monoamine reuptake inhibitor
  46. GC52128 AOD-9604 A synthetic lipolytic peptide
  47. GC52125 T-1095 An SGLT1 and SGLT2 inhibitor
  48. GC20007 Ginsenoside CK

    20(S)-人参皂苷 C-K

    A metabolite of ginsenoside Rb1 with diverse biological activity
  49. GC52071 10-oxo-12(Z)-Octadecenoic Acid

    10-keto-12Z-Octadecenoic Acid, 10-oxo-12-cis-Octadecenoic Acid

     A metabolite of linoleic acid and an activator of TRPV1
  50. GC52047 Fustin

    黄颜木素,(±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone

     A flavanone with diverse biological activities
  51. GC52032 Montbretin A

    MbA

     An acylated flavonol glycoside with antidiabetic activity

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