PIKfyve(含FYVE指磷酸肌醇激酶)
PIKfyve (1-phosphatidylinositol 3-phosphate 5-kinase) catalyzes the production of PtdIns5P and PtdIns(3,5)biphosphate from the phosphorylation o f D-5 position in PtdIns and phosphatidylinositol-3-phosphate. It is involved in endosome carrier vesicle biogenesis in early endosomes and endomembrane homeostasis.
Products for PIKfyve
- Cat.No. 产品名称 Information
- GC74025 PIKfyve-IN-3 PIKfyve-IN-3(化合物L22)与PIKfyve激酶具有显著的相互作用,Kd值为0.47nM。
- GC73606 PIK5-12d PIK5-12d是PROTAC PIKfyve降降剂(DC50: 1.48 nM)。
- GC69711 PIKfyve-IN-1 PIKfyve-IN-1 是一种高效且具有细胞活性的化学探针,可抑制 3 磷酸磷脂酰肌醇 5-激酶 (PIKfyve),IC50 值为 6.9 nM。PIKfyve-IN-1 可用于病毒学中 PIKfyve 的研究。
- GC66013 MOMIPP MOMIPP,一种巨胞饮作用的诱导剂,是一种 PIKfyve 抑制剂。MOMIPP 可穿过血脑屏障 (BBB)。
- GC31661 APY0201 An inhibitor of PIKFYVE
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GC10982
YM201636
6-氨基-N-[3-[4-(4-吗啉基)吡啶并[3',2':4,5]呋喃并[3,2-D]嘧啶-2-基]苯基]-3-吡啶甲酰胺
Inhibitor of PIKfyve