Proteases(蛋白酶)

Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.

Products for Proteases

Cat.No. 产品名称 Information
GC41951 17(R)-Resolvin D1
Aspirin-triggered Resolvin D1
An aspirin-triggered epimer of RvD1
GC41940 15-OxoEDE
15KEDE
A PUFA produced by oxidation of 15-HEDE
GC41938 15-Lipoxygenase Inhibitor 1
15LO Inhibitor 1
An inhibitor of 15-LO
GC41937 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
15-KETO-比马前列素
A potential metabolite of Bimatoprost
GC41927 15(S)-HETrE A 5-LO inhibitor
GC41926 15(S)-HETE-biotin
15(S)-Hydroxyeicosatetraenoic Acid-biotin
Used to detect 15(S)-HETE binding proteins and/or receptors
GC41925 15(S)-HETE Ethanolamide
15(S)-HAEA, 15(S)-Hydroxyeicosatetraenoic Acid Ethanolamide
A CB₁ receptor ligand and FAAH inhibitor
GC41911 13-epi-12-oxo Phytodienoic Acid
13-EPI-12-氧代植物二烯酸
A lipoxygenase metabolite of α-linolenic acid
GC41900 13(S)-HpOTrE(γ) Produced by the action of soybean LO-1 on γ-linolenic acid
GC41899 13(S)-HpOTrE
A product of soybean LO-2 metabolism of α-linolenic acid
GC41898 13(S)-HOTrE(γ) A 15-LO product derived from GLA
GC41897 13(S)-HOTrE A 15-LO product derived from GLA
GC41896 13(S)-HODE-biotin A biotinylated PUFA
GC41882 12(S)-HETrE An inhibitor of platelet activation
GC41837 1,3,7-Trimethyluric Acid
1,3,7-三甲基尿酸,8-oxo Caffeine, NSC 11259
A metabolite of caffeine
GC41825 1,2-Dipalmitoyl-sn-glycero-3-phosphate (sodium salt)
1,2-Dipalmitoyl-sn-glycero-3-phosphatidic Acid, 1,2-Dipalmyitoyl-sn-glycero-3-phophate, 1,2-DPPA, 16:0/16:0-PA
1,2-Dipalmitoyl-sn-glycero-3-phosphate (sodium salt)（16:0/16:0-PA）是一种磷脂，含有插入到sn-1和sn-2位置的长链（16:0）棕榈酸，能够用于制备脂质体、胶束和人工膜。
GC41822 1,2-Dipalmitoyl-sn-glycero-3-PE
L-磷脂酰乙醇胺
A phospholipid
GC41804 1,2-Dimyristoyl-sn-glycero-3-PE
1,2-十四酰基磷脂酰乙醇胺
A phospholipid
GC41778 1,2,3-Tripalmitoyl-rac-glycerol
(三)棕榈酸甘油酯
A triacylglycerol
GC41776 1,2,3-Trioleoyl-rac-glycerol
三油酸甘油酯
A triacylglycerol
GC41774 1,2,3-Trimyristoyl-rac-glycerol
三肉豆蔻酸甘油酯
A triacylglycerol
GC41770 1,2,3-Trieicosapentaenoyl-rac-glycerol
二十碳五烯酸甘油三酯(CIS-5,8,11,14,17)
A polyunsaturated triacylglycerol
GC41768 1,2,3-Tridecanoyl-rac-glycerol
甘油三癸酸酯; Tricaprin; Glyceryl tridecanoate
A triacylglycerol
GC41767 1,2,3-Triarachidonoyl-rac-glycerol
三花生精
A triacylglycerol
GC41765 1,2,3-Tri-13(Z)-Docosenoyl-rac-glycerol
三芥精
A triacylglycerol
GC41736 (S)-Dibutyl 3-Hydroxybutyl Phosphate
(S)TBPOH
A compound produced from tributyl phosphate
GC41722 (R,S)-Carvedilol Glucuronide
卡维地洛葡糖苷酸
A phase II metabolite of carvedilol
GC41721 (R)-α-Lipoic Acid
硫辛酸; (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid
A cyclic disulfide antioxidant
GC41694 (3S)-hydroxy Quinidine
(3S)-3-羟基奎尼定
An active quinidine metabolite
GC41671 (±)-Equol 4'-sulfate (sodium salt)
R,S-Equol 4'-Sulfate
A metabolite of (±)-equol
GC41670 (±)-Epinephrine (hydrochloride)
肾上腺素盐酸盐
An adrenergic receptor agonist
GC41666 (±)9-HODE cholesteryl ester A racemic monohydroxy fatty acid cholesteryl ester
GC41661 (±)-4-hydroxy Propranolol β-D-Glucuronide
(+/-)-4-羟基普萘洛尔葡糖苷酸
A metabolite of propranolol
GC41649 (±)13-HODE cholesteryl ester A 15-LO product derived from cholesteryl linoleate
GC41642 9(E),11(E),13(E)-Octadecatrienoic Acid
β-Eleostearic Acid, β-ESA
A polyunsaturated fatty acid
GC41638 TSI-01 TSI-01是溶血磷脂酰胆碱酰基转移酶2（LPCAT2）的选择性抑制剂，对人 LPCAT2和LPCAT1的IC₅₀值分别为0.47和3.02µM。
GC41586 cis-Petroselinic Acid
岩芹酸；芹子酸；岩芹炔酸；十八碳 6 烯酸
A monounsaturated fatty acid
GC41565 3-hydroxy Medetomidine
羟基美托咪定
A metabolite of medetomidine
GC41562 Taurohyodeoxycholic Acid
牛磺猪去氧胆酸
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
GC41552 ω-3 Arachidonic Acid
ω3 AA
A rare, natural 20:4 ω-3 polyunsaturated fatty acid
GC41532 Benzisoxazole Hsp90 Inhibitor
BHI
Hsp90 chaperone inhibitor
GC41531 Anacardic Acid Triene
Anacardic Acid 15:3
A polyunsaturated form of anacardic acid
GC41529 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
EFOX, 17oxo4(Z),7(Z),10(Z),13(Z),15(E),19(Z)DHA, 17-oxo-DHA
A metabolite of DHA with anti-inflammatory properties
GC41480 3'-hydroxy Lidocaine
3'-羟基利多卡因
A metabolite of lidocaine
GC41478 L-α-Hydroxyglutaric Acid
S-2-羟基戊二酸,2(S)-HG, 2(S)-Hydroxyglutaric Acid, L-2-HG, L-2-Hydroxyglutaric Acid
L-α-羟基戊二酸是生命各个领域的重要代谢产物。
GC41477 3-Hydroxyglutaric Acid
3-羟基戊二酸
A biomarker for GCDH deficiency
GC41424 6(S)-Lipoxin A4
5(S),6(S)-Lipoxin A4, 6-epi-Lipoxin A4, 6(S)-LXA4, 5(S),6(S),15(S)-TriHETE
An isomer of LXA₄
GC41421 20-hydroxy Leukotriene B4
20-羟基白三烯B4
A LTB₄ metabolite
GC41415 15(R)-Lipoxin A4
AT-Lipoxin A4
An aspirin-triggered lipoxin
GC41403 15(S)-HpEDE A 15-LO product derived from eicosadienoic acid