Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
Products for Proteases
- Aminopeptidase(20)
- ACE(73)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(24)
- Gamma Secretase(42)
- HCV Protease(35)
- HSP(102)
- HIV Integrase(28)
- HIV Protease(34)
- MMP(191)
- NS3/4a protease(4)
- Serine Protease(15)
- Thrombin(44)
- Urokinase(2)
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(63)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(505)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1719)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(34)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(262)
- Mitochondrial Metabolism(248)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(13)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(115)
- PCSK9(13)
- ADAMTS(1)
- TrxR(1)
- DGK(3)
- Cat.No. 产品名称 Information
-
GC48086
Solanesol
茄尼醇
A trisesquiterpenoid with diverse biological activities -
GC48083
sn-Glycerol-3-phosphate (cyclohexyl ammonium salt hydrate)
G3P
A neuropeptide with diverse biological activities -
GC48077
SHS4121705
A mitochondrial uncoupler
-
GC48069
Saxagliptin-13C-d2 (hydrochloride)
A neuropeptide with diverse biological activities
-
GC48062
RU-SKI 201 (hydrochloride)
A neuropeptide with diverse biological activities
-
GC48060
Rosuvastatin-d6 (sodium salt)
瑞舒伐他汀-D6二钠盐
An internal standard for the quantification of rosuvastatin -
GC48045
Resolvin E4
RvE4
A specialized pro-resolving mediator -
GC48044
Resolvin E1-d4
RvE1d4, 5S,12R,18R-trihydroxy-EPA-d4, 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-EPA-d4, 5,12,18R-triHEPE-d4
A neuropeptide with diverse biological activities -
GC48043
Resolvin D3-d5
RvD3-d5
A neuropeptide with diverse biological activities -
GC48042
Resolvin D2-d5
RvD2-d5
An internal standard for the quantification of RvD2 -
GC48041
Resolvin D1-d5
RvD1-d5
An internal standard for the quantification of RvD1 -
GC48035
RCTR1
Resolvin Glutathione Conjugate in Tissue Regeneration 1, Resolvin Sulfido Conjugate 1
A specialized pro-resolving mediator -
GC48030
RC574
An inhibitor of ferroptosis
-
GC47980
Propionyl-L-carnitine-d3 (chloride)
L-Propionylcarnitine-d3 chloride; ST-261-d3
An internal standard for the quantification of propionyl-L-carnitine
-
GC47965
Pomalidomide-d5
泊马度胺杂质,CC-4047-d5
An internal standard for the quantification of pomalidomide -
GC47923
Paraxanthine-d6
1,7-Dimethylxanthine-d6
An internal standard for the quantification of paraxanthine -
GC47868
Palmitoyl-L-carnitine-d3 (chloride)
十六烷酰基-L-肉碱-d3 (盐酸盐)
Palmitoyl-L-carnitine-d3 (chloride)是Palmitoyl-L-carnitine的氘化形式,主要在质谱脂质分析中用作内标。 -
GC47847
Oxamyl
杀线威
A carbamate pesticide -
GC47826
Omeprazole sulfone-d3
OMEP sulfone-d3, OMP sulfone-d3, OMZ sulfone-d3
An internal standard for the quantification of omeprazole sulfone -
GC47816
Octanoyl-L-carnitine-d3 (chloride)
辛酰基-L-肉碱-d3 (盐酸盐)
An internal standard for the quantification of octanoyl-L-carnitine -
GC47789
N-Oleoyl Glutamine
N-Oleoyl Gln
An endogenous N-acyl amine -
GC47757
N-Desmethylclozapine-d8
Norclozapine-d8; Desmethylclozapine-d8; Normethylclozapine-d8
An internal standard for the quantification of N-desmethylclozapine -
GC47756
N-desmethyl Rosuvastatin (sodium salt hydrate)
An active metabolite of rosuvastatin
-
GC47751
Nateglinide-d5
那格列奈-D5,A4166 D5; Senaglinide D5
An internal standard for the quantification of nateglinide -
GC47747
Napyradiomycin A1
A fungal metabolite with diverse biological activities
-
GC47746
NAP 226-90
3-(1-(S)-(N,N-二甲基氨基)乙基)苯酚
A metabolite of rivastigmine -
GC47740
NADP+ (hydrate)
Coenzyme II, β-NADP, Nicotinamide adenine dinucleotide phosphate, TPN
A neuropeptide with diverse biological activities -
GC47739
NADH (sodium salt hydrate)
还原型辅酶Ⅰ
A reduced form of NAD+ -
GC47735
N-acetyl Desethylchloroquine-d4
N-acetyl-(mono) Desethylchloroquine
An internal standard for the quantification of N-acetyl desethylchloroquine -
GC47716
Myxochelin A
(S)-Myxochelin A
A microbial metabolite with diverse biological activities -
GC47715
Myristoyl-L-carnitine-d3 (chloride)
十四烷酰基-L-肉碱-d3 (盐酸盐)
An internal standard for the quantification of myristoyl-L-carnitine -
GC47714
Myristoyl-L-carnitine-14,14,14-d3 (chloride)
CAR 14:0-d3, C14:0 Carnitine-d3, L-Carnitine myristoyl ester-d3, L-Carnitine tetradecanoyl ester-d3, L-Myristoylcarnitine-d3, Tetradecanoyl-L-carnitine-d3, L-Tetradecanoylcarnitine-d3
A neuropeptide with diverse biological activities -
GC47712
Mycophenolate Mofetil-d4
吗替麦考酚酯 d4
An internal standard for the quantification of mycophenolate mofetil -
GC47708
MPro Inhibitor 11b
An inhibitor of SARS-CoV-2 Mpro
-
GC47707
MPro Inhibitor 11a
An inhibitor of SARS-CoV-2 Mpro
-
GC47701
Montelukast-d6 (sodium salt)
MK-476-d6
A neuropeptide with diverse biological activities -
GC47685
MIT-PZR
A mitochondria-targeted fluorescent probe
-
GC47684
MitoP-d15
MitoPhenol-d15
A neuropeptide with diverse biological activities -
GC47683
MitoB-d15
A neuropeptide with diverse biological activities
-
GC47663
Methylene Blue (hydrate)
亚甲基蓝水合物,Basic Blue 9 hydrate; CI-52015 hydrate; Methylthioninium chloride hydrate
A cationic dye with diverse biological activities -
GC47660
Methyl Parathion
甲基对硫磷
An organophosphate insecticide -
GC47650
Methotrexate-d3
甲氨蝶呤 d3
An internal standard for the quantification of methotrexate -
GC47648
Methomyl
灭多威
A carbamate insecticide -
GC47647
Methiocarb-d3
灭虫威-D3,Mercaptodimethur-d3
An internal standard for the quantification of methiocarb -
GC47646
Methiocarb
甲硫威
A carbamate pesticide -
GC47620
Mensacarcin
A bacterial metabolite with anticancer activity
-
GC47599
Maresin 2-d5
13R,14S-diHDHA-d5, 13R,14S-dihydroxy Docosahexaenoic Acid-d5, MaR2-d5
A neuropeptide with diverse biological activities -
GC47598
Maresin 1-d5
7(R)-MaR1-d5, 7(R)-Maresin 1-d5
A neuropeptide with diverse biological activities -
GC47575
Loratadine-d5
五氘代氯雷他定,Loratidine-d5; SCH 29851-d5
An internal standard for the quantification of loratadine -
GC47574
Loratadine-d4
Loratidine-d4; SCH 29851-d4
A neuropeptide with diverse biological activities