Proteases(蛋白酶)

Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.

Products for Proteases

Cat.No. 产品名称 Information
GC47573 Lopinavir-d8 An internal standard for the quantification of lopinavir
GC47570 Lipoxygenin An inhibitor of 5-LO
GC47569 Lipoxin A4-d5
LXA4-d5
An internal standard for the quantification of Lipoxin A₄
GC47560 Leukotriene E4-d5
LTE4-d5
An internal standard for the quantification of leukotriene E₄
GC47559 Leukotriene D4-d5
LTD4d5
An internal standard for the quantification of LTD₄
GC47558 Leukotriene C4-d5 methyl ester
LTC4d5 methyl ester
A neuropeptide with diverse biological activities
GC47556 Leukotriene B4-d4
LTB4-d4; 5(S),12(R)-DiHETE-d4
An internal standard for the quantification of leukotriene B₄
GC47555 Leukotriene A4-d5 methyl ester
LTA4d5 methyl ester
A neuropeptide with diverse biological activities
GC47548 L-Carnitine-d3 (chloride)
L-肉毒碱-(甲基-D3)盐酸盐,(R)-Carnitine-d3 hydrochloride
An internal standard for the quantification of L-carnitine
GC47547 Lauroyl-L-carnitine-d3 (chloride)
C12:0 Carnitine-d3, CAR 12:0-d3, L-Carnitine lauroyl ester-d3, L-Lauroylcarnitine-d3
A neuropeptide with diverse biological activities
GC47546 Lauroyl-L-carnitine-12,12,12-d3 (chloride)
CAR 12:0-d3, C12:0 Carnitine-d3, L-Carnitine lauroyl ester-d3, L-Lauroylcarnitine-d3
A neuropeptide with diverse biological activities
GC47531 Kresoxim-methyl
醚菌酯,BAS 490 F
A fungicide
GC47470 Isovaleryl-L-carnitine-d3 (chloride)
CAR 5:0-d3, C5:0 Carnitine-d3, L-Carnitine isovaleryl ester-d3, L-Isovalerylcarnitine-d3
A neuropeptide with diverse biological activities
GC47455 Indinavir-d6
茚地那韦-D6,MK-639-d6 free base; L-735524-d6 free base
An internal standard for the quantification of indinavir
GC47431 Hexanoyl-L-carnitine-d3 (chloride)
CAR 6:0-d3, L-Caproylcarnitine-d3, Caproyl-L-Carnitine-d3, C6:0 Carnitine-d3, L-Carnitine caproyl ester-d3, L-Carnitine hexanoyl ester-d3, L-Hexanoylcarnitine-d3
A neuropeptide with diverse biological activities
GC47430 Hexanoyl-L-carnitine (chloride)
Caproyl-L-Carnitine, L-Caproylcarnitine, CAR 6:0, C6:0 Carnitine, L-Carnitine caproyl ester, L-Carnitine hexanoyl ester, L-Hexanoylcarnitine
A medium-chain acylcarnitine
GC47399 Geranylgeranoic Acid
GGA

An isoprenoid with anticancer activity
GC47370 Fosinopril (sodium salt)
福辛普利钠; SQ28555
A prodrug form of fosinoprilat
GC47366 Flurbiprofen-d3
氟比洛芬-D3氘代物,dl-Flurbiprofen-d3
An internal standard for the quantification of flurbiprofen
GC47351 Fingolimod-d4
芬戈莫德-D4,FTY720 free based-d4
An internal standard for the quantification of fingolimod
GC47339 Fenpropimorph
顺-4-叔丁基苯基(-2-甲基丙基)-2,6-二甲基吗啉
A fungicide that inhibits the sterol pathway
GC47330 Faldaprevir-d6
BI-201335-d6
Faldaprevir-d6 是氘标记的 Faldaprevir。
GC47326 Etoxazole
乙螨唑
An organofluorine acaricide
GC47323 Etofenamate-d4
依托芬那酯 d4
An internal standard for the quantification of etofenamate
GC47320 Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)
17α-Ethynylestradiol 3-Glucuronide
A metabolite of ethynyl estradiol
GC47312 Etherolenic Acid
(9Z,11E,1'E,3'Z)-12-(1',3'-hexadenyloxy)-9,11-Dodecadienoic Acid
A divinyl ether oxylipin
GC47274 DS44960156 An MTHFD2 inhibitor
GC47243 DL-Carnitine-d9 (chloride)
DL-肉碱盐酸盐-D9氘代,DL-Carnitine-d9 chloride
An internal standard for the quantification of carnitine
GC47240 Diquat-d4 (bromide) A neuropeptide with diverse biological activities
GC47239 Diquat-d12 (bromide) A neuropeptide with diverse biological activities
GC47238 Diquat (bromide)
敌草快
An herbicide
GC47196 Desloratadine-d4
Sch34117-d4
An internal standard for the quantification of desloratadine
GC47195 Desethylchloroquine-d4
N-Desethylchloroquine-d4
An internal standard for the quantification of desethylchloroquine
GC47193 Desethyl Hydroxychloroquine-d4
Desethylhydroxychloroquine-d4
An internal standard for the quantification of desethyl hydroxychloroquine
GC47178 Decanoyl-L-carnitine-d3 (chloride)
癸酰基-L-肉碱-d3
A neuropeptide with diverse biological activities
GC47177 Decanoyl-L-carnitine (hydrate)
CAR 10:0, C10:0 Carnitine, L-Carnitine decanoyl ester, (-)-Decanoylcarnitine, L-Decanoylcarnitine
A neuropeptide with diverse biological activities
GC47176 Decanoyl-Coenzyme A (hydrate)
Decanoyl-CoA
A neuropeptide with diverse biological activities
GC47173 Darunavir-d9
九氘代地瑞拉为,TMC114-d9; UIC-94017-d9
An internal standard for the quantification of darunavir
GC47160 Cystamine-d8 (hydrochloride) A neuropeptide with diverse biological activities
GC47123 Coumarin-Quinone Conjugate A fluorescent substrate for NADH:ubiquinone oxidoreductases
GC47117 Colchicine-d6
秋水仙素 d6
An internal standard for the quantification of colchicine
GC47116 Coenzyme Q10-d6
辅酶Q10-D6,CoQ10-d6; Ubiquinone-10-d6
An internal standard for the quantification of CoQ₁₀
GC47114 Coenzyme A (lithium salt hydrate)
CoA
An essential cofactor in enzymatic acetyl transfer reactions
GC47096 Citrinin-13C13
(-)-Citrinin-13C13, CTN-13C13
A neuropeptide with diverse biological activities
GC47087 Cilastatin-15N-d3
MK0791-15N,d3
A neuropeptide with diverse biological activities
GC47065 CAY10773 A derivative of sorafenib
GC47042 Carfilzomib-d8
来那度胺-D8
An internal standard for the quantification of carfilzomib
GC47040 Carebastine-d5
卡依巴司丁 d5
An internal standard for the quantification of carebastine
GC47022 Camostat-d6 (hydrochloride) A neuropeptide with diverse biological activities
GC46972 Butyryl-L-carnitine-d3 (chloride)
丁酰基-L-肉碱-d3 （盐酸盐）
An internal standard for the quantification of butyryl-L-carnitine