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Home >> Signaling Pathways >> Proteases >> Drug Metabolite

Drug Metabolite(药物代谢物)

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products for  Drug Metabolite

  1. Cat.No. 产品名称 Information
  2. GC33738 3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride)

    2-甲氧基-4-(2-氨基乙基)苯酚,3-O-methyl Dopamine hydrochloride

     A natural metabolite of dopamine
  3. GC33672 Lurasidone Metabolite 14283 hydrochloride

    鲁拉西酮缓解期代谢物14283

     LurasidoneMetabolite14283hydrochloride是Lurasidone的主要的活性代谢物。
  4. GC33579 Carvedilol metabolite 4-Hydroxyphenyl Carvedilol

    卡维地洛对羟基代谢物,4-Hydroxyphenyl Carvedilol; 4-Hydroxycarvedilol

     An active metabolite of carvedilol
  5. GC33578 Ivabradine metabolite N-Demethyl Ivabradine hydrochloride

    N-去甲盐酸伊伐布雷定,N-Demethyl ivabradine hydrochloride

     An active metabolite of ivabradine
  6. GC33571 Duloxetine metabolite Para-Naphthol Duloxetine (Para-Naphthol duloxetine)

    度洛西汀代谢物; Para-Naphthol duloxetine

     对萘酚度洛西汀是度洛西汀的代谢产物，度洛西汀是一种血清素去甲肾上腺素再摄取抑制剂 (SNRI)。
  7. GC33564 Lurasidone metabolite 14326

    鲁拉西酮缓解期代谢物14326

     An active metabolite of lurasidone
  8. GC33563 Netupitant metabolite N-desmethyl Netupitant (N-desmethyl Netupitant)

    奈妥匹坦杂质B,N-desmethyl Netupitant

    N-desmethyl Netupitant 是 Netupitant 的代谢物，Netupitant 是一种止吐药。
  9. GC33559 Netupitant metabolite Monohydroxy Netupitant (Monohydroxy Netupitant)

    奈妥匹坦杂质A,Monohydroxy Netupitant

     Monohydroxy Netupitant 是 Netupitant 的代谢物，Netupitant 是一种高选择性的 NK1 受体拮抗剂。
  10. GC33558 Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen)

    对乙酰氨基酚代谢物; 3-Hydroxyacetaminophen

     3-羟基-对乙酰氨基酚是对乙酰氨基酚的代谢物，它是一种止痛药。
  11. GC33548 Netupitant metabolite Netupitant N-oxide (Netupitant N-oxide)

    奈妥吡坦杂质,Netupitant N-oxide

    A metabolite of netupitant
  12. GC33532 Norgestimate metabolite Norelgestromin (17-Deacetyl norgestimate)

    甲基孕酮,17-Deacetyl norgestimate; 17-Deacylnorgestimate

     An active metabolite of norgestimate
  13. GC33495 N-Desmethyl imatinib

    N-去甲基伊马替尼; Norimatinib; Imatinib metabolite N-Desmethyl imatinib

     A major active metabolite of imatinib
  14. GC33484 Ampyrone (4-Aminoantipyrine)

    4-氨基安替比林

     4-Aminoantipyrine(Ampyrone) is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used as a reagent for biochemical reactions producing peroxides or phenols.
  15. GC33452 Niraparib metabolite M1 (Niraparib carboxylic acid metabolite M1)

    尼拉帕尼代谢物; Niraparib carboxylic acid metabolite M1; M1 metabolite of niraparib

     Niraparib 代谢物 M1 (Niraparib carboxy acid metabolite M1) 是 niraparib 的代谢物，后者作为一种新型聚 (ADP-核糖) 聚合酶 (PARP) 抑制剂。
  16. GC33438 Hydroxy Itraconazole

    羟基伊曲康唑; Itraconazole metabolite Hydroxy Itraconazole; R-63373

     A metabolite of itraconazole
  17. GC33333 Regorafénib N-oxyde M2

    瑞格非尼 N-氧化物(M2代谢物)杂质13

     An active metabolite of regorafenib
  18. GC33072 AZ7550 An active metabolite of AZ 9291
  19. GC32535 Modecainide (BMY 40327)

    莫地卡尼,BMY 40327; MJ 14030

     Modecainide (BMY 40327) 是 Encainide 的主要代谢物，Encainide 是一种抗心律失常药物。
  20. GC32519 Vinburnine ((-)-Eburnamonine)

    长春布宁,(-)-Eburnamonine; (-)-Vincamone

     Vinburnine ((-)-Eburnamonine, Vincamone, L-Eburnamonine) is a vasodilator. It is a vinca alkaloid and a metabolite of vincamine.
  21. GC32518 Norverapamil hydrochloride ((±)-Norverapamil hydrochloride)

    盐酸去甲维拉帕米; (±)-Norverapamil hydrochloride; D591 hydrochloride

     An L-type calcium channel blocker
  22. GC32482 Hydroxyhexamide ((±)-Hydroxyhexamid)

    乙酸己脲

     Hydroxyhexamide is a pharmacologically active metabolite of acetohexamide, which is a sulfonylurea hypoglycemic agent.
  23. GC31734 S-methyl-KE-298 (M-2)

    M-2

    S-methyl-KE-298 (M-2) 是 KE-298 的活性代谢物。
  24. GC31328 Thyroxine sulfate (T4 Sulfate)

    T4磺酸酯,T4 Sulfate

     硫酸甲状腺素 (T4 Sulfate) 是一种甲状腺激素代谢物。
  25. GC30994 Vanilpyruvic acid (Vanylpyruvic acid)

    4-羟基-3-甲氧基苯基丙酮酸,Vanylpyruvic acid

     香草丙酮酸 (Vanylpyruvic acid) 是儿茶酚胺代谢物和香草乳酸的前体。
  26. GC30505 N-Desmethyl Clomipramine D3 hydrochloride (Desmethylclomipramine D3 hydrochloride)

    去甲氯米帕明-D3盐酸盐,Desmethylclomipramine D3 hydrochloride

    N-Desmethyl Clomipramine D3 hydrochloride (Desmethylclomipramine D3 hydrochloride) 是氘标记的 N-Desmethyl Clomipramine。
  27. GC19442 15-Acetyldeoxy Nivalenol

    15-O-乙酰脱氧瓜萎镰菌醇

     A natural mycotoxin
  28. GC18831 Tolmetin β-D-Glucuronide A major phase II metabolite of tolmetin
  29. GC18702 Propiverine N-oxide (hydrochloride) An active propiverine metabolite
  30. GC18654 8-hydroxy Loxapine

    8-OH Loxapine

     A loxapine metabolite
  31. GC18632 6-hydroxy Bexarotene

    6-羟基蓓萨罗丁

     An oxidative metabolite of bexarotene
  32. GC18622 (2'S)-Nicotine-1-oxide

    (2'S)-尼古丁氧化物

     A nicotine metabolite
  33. GC18596 (±)-2-propyl-4-Pentenoic Acid

    2-丙基-4-五烯酸,2-Allylpentanoic Acid, 4-ene VPA

    A metabolite of valproic acid
  34. GC18582 5'-hydroxy Meloxicam

    5'-羟基美洛昔康

     A metabolite of meloxicam
  35. GC18569 Propofol β-D-Glucuronide

    2,6-二异丙基Β-D-吡喃葡萄糖酸

    A metabolite of propofol
  36. GC18542 5,6-dihydro-5-Fluorouracil

    5-氟二氢嘧啶-2,4-二酮

     A metabolite of 5-FU
  37. GC18539 all-trans-4-hydroxy Retinoic Acid

    维甲酸杂质

    A metabolite of all-trans retinoic acid
  38. GC18527 4'-hydroxy Flurbiprofen

    4-羟基氟吡洛芬

     A major active metabolite of flurbiprofen
  39. GC18466 5,6-epoxy-13-cis Retinoic Acid

    异维A酸EP杂质G

     A metabolite of 13-cis retinoic acid
  40. GC18455 Digoxigenin Monodigitoxoside

    地高辛杂质D

     A Na+/K+-ATPase inhibitor
  41. GC18439 Doxorubicinone

    阿霉酮,Adriamycin aglycone; Adriamycinone

     A metabolite of doxorubicin
  42. GC18425 4-hydroxy Atorvastatin lactone

    P-羟基阿伐他汀内酯

     A metabolite of atorvastatin
  43. GC18417 4-hydroxy Xylazine

    4-羟基塞拉嗪

     A xylazine metabolite
  44. GC18335 6β-hydroxy Dexamethasone

    6-羟基地塞米松

     A metabolite of dexamethasone
  45. GC18219 6-hydroxy Warfarin

    3-(Α-丙酮基苄基)-4,6-二羟基香豆素

     A phase I metabolite of (+)-warfarin
  46. GC18194 4-Epidoxycycline

    强力霉素

     A metabolite of doxycycline
  47. GC15168 Urolithin A

    尿石素A

    A metabolite of ellagic acid with diverse biological activities
  48. GC16333 Cycloguanil (hydrochloride)

    环氯胍盐酸盐

     The active metabolite of proguanil
  49. GC11989 Nortriptyline (hydrochloride)

    盐酸去甲替林; Desmethylamitriptyline hydrochloride; Desitriptilina hydrochloride

     A tricyclic antidepressant
  50. GC11155 Omeprazole sulfone

    奥美拉唑杂质A,Omeprazole sulfone; Omeprazole sulphone

     The major metabolite of omeprazole
  51. GC16553 N-Desmethylclozapine

    N-去甲基氯氮平; Norclozapine; Desmethylclozapine; Normethylclozapine

     An active metabolite of clozapine

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