Drug Metabolite(药物代谢物)

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products for Drug Metabolite

Cat.No. 产品名称 Information
GC65956 Edoxaban M4
D21-2393
Edoxaban M4 是 Edoxaban 的活性代谢物，具有可重复性的、浓度依赖性的基质效应。Edoxaban (DU-176) 是选择性的、有效和口服活性的 factor Xa (FXa) 抑制剂。
GC20062 trans-3'-Hydroxycotinine
3'R,5'S)-3'-羟基可替宁,3HC
A metabolite of nicotine
GC52177 Perphenazine Sulfoxide
奋乃静亚砜
An active metabolite of perphenazine
GC52173 N-desmethyl-Doxylamine (succinate)
氢催化杂质
A metabolite of doxylamine
GC52168 Aripiprazole N,N-dioxide
阿立哌唑,1,4-二氮氧化物
A metabolite of aripiprazole
GC52132 N-desmethyl Diltiazem (hydrochloride)
盐酸地尔硫卓杂质D
An active metabolite of diltiazem
GC20007 Ginsenoside CK
20(S)-人参皂苷 C-K
A metabolite of ginsenoside Rb1 with diverse biological activity
GC65324 RP101988 RP101442 是 Ozanimod 的主要的活性代谢物，是一种选择性强的 S1PR1 激动剂，对 S1PR1 和 S1P5R 的 EC50 分别为 0.19 nM 和 32.8 nM。
GC64759 Dimethadione
5,5-二甲基噁唑烷-2,4-二酮
5,5-Dimethyloxazolidine-2,4-dione (Dimethadione, Dimethyloxazolidinedione, Dimethadion) is an anticonvulsant that is the active metabolite of trimethadione.
GC64720 Imipramine N-oxide
氧丙咪嗪
Imipramine N-oxide 是 Imipramine 的代谢物。Imipramine 是一种叔胺三环类抗抑郁药。
GC64511 Hydroxy ritonavir
羟基利托那韦
Hydroxy ritonavir 是 Ritonavir 的代谢物。Ritonavir 是用于研究 HIV 感染和 AIDS 的 HIV 蛋白酶的抑制剂。
GC64469 Ribavirin carboxylic acid
利巴韦林羧酸
Ribavirin carboxylic acid (TR-COOH) 是一种 ribavirin 的代谢物 (metabolite)，ribavirin 具有强烈的抗病毒活性。
GC52076 Temozolomide Acid
3,4-二氢-3-甲基-4-氧代咪唑并[5,1-D]-1,2,3,5-四嗪-8-甲酰胺酸
An active metabolite of temozolomide
GC52074 Loratadine N-oxide
氯雷他定N-氧化物
A metabolite of loratadine
GC52060 Trimipramine N-oxide
10,11-二氢-N,N,BETA-三甲基-5H-二苯并[B,F]氮杂卓-5-丙胺N-氧化物
An active metabolite of trimipramine
GC52059 AMOZ
硝基呋喃代谢物AMOZ,3-Amino-5-morpholinomethyl-2-oxazolidone
A metabolite of furaltadone
GC52054 Ranitidine S-oxide
雷尼替丁EP杂质C (Ranitidine S-Oxide)
A metabolite of ranitidine
GC52052 Dofetilide N-oxide
多非利特氮氧化物,UK-116856
A metabolite of dofetilide
GC52045 N-desmethyl Azelastine
氮卓斯汀杂质
An active metabolite of azelastine
GC52035 Esmolol Acid (hydrochloride)
艾司洛尔酸钠
An active metabolite of esmolol
GC52033 S-Methyl-D-penicillamine A metabolite of D-penicillamine
GC52029 2-Aminoflubendazole
2-氨基氟苯咪唑
A metabolite of flubendazole
GC52024 Aripiprazole N-oxide
阿立哌唑-N1-氧化物
A metabolite of aripiprazole
GC52019 Norpropranolol (hydrochloride)
(±)-Desisopropylpropranolol, N-Desisopropylpropranolol
An active metabolite of propranolol
GC52007 N-hydroxylamine Dapsone
羟胺氨苯砜
An active metabolite of dapsone
GC52005 Triazolomethylindole-3-acetic Acid
三唑甲基吲哚-3-乙酸
A metabolite of rizatriptan
GC49875 (±)-N-desmethyl Venlafaxine (hydrochloride)
盐酸文拉法辛杂质D
A minor active metabolite of venlafaxine
GC49869 3-Methoxytyrosine
2-氨基-3-(4-羟基-3-甲氧基苯基)丙酸
An active metabolite of L-DOPA
GC49866 Desmethyl Carvedilol
O-去甲卡维地洛
An active metabolite of carvedilol
GC49863 Cytarabine 5′-monophosphate
ara-CMP, 1-β-D-Arabinofuranosylcytosine 5'-monophosphate, Cytosine Arabinoside monophosphate, NSC 99445
An active metabolite of cytarabine
GC49858 Desipramine-d4 (hydrochloride)
盐酸去郁敏D4
An internal standard for the quantification of desipramine
GC49855 Harmalol (hydrochloride hydrate)
骆驼蓬酚盐酸盐(二水)
A β-carboline alkaloid and an active metabolite of harmaline
GC49851 Norquetiapine
11-(1-哌嗪基)二苯并[B,F][1,4]硫氮杂卓
An active metabolite of quetiapine
GC49845 Piribedil N-oxide
吡贝地尔氮氧化物
A metabolite of piribedil
GC49843 Aposcopolamine
东茛菪碱
A tropane alkaloid and an active metabolite of scopolamine
GC49842 Digoxigenin Bisdigitoxoside
Bisdigoxigenin
A Na⁺/K⁺-ATPase inhibitor
GC49832 Hydroxymetronidazole
羟基甲硝唑,Metronidazole-OH
An active metabolite of metronidazole
GC49823 2′-C-β-Methylguanosine
2'-C-甲基鸟苷
An active nucleoside metabolite of BMS-986094
GC49820 10,11-dihydro-10,11-dihydroxy Carbamazepine
奥卡西平杂质
A metabolite of carbamazepine and oxcarbazepine
GC49817 Desethoxy Quetiapine (hydrochloride)
喹硫平羟基杂质二盐酸盐
An active metabolite of quetiapine
GC49794 N-desmethyl Trimipramine
N-去甲曲米帕明
An active metabolite of trimipramine
GC49780 Omeprazole N-oxide
奥美拉唑N-氧化物
A metabolite of omeprazole
GC49773 Albendazole sulfone-d3
阿苯哒唑砜-D3
An internal standard for the quantification of albendazole sulfone
GC49764 N-desmethyl Asenapine
阿塞那平D4
A metabolite of asenapine
GC49760 SN-38 Glucuronide
SN-38葡糖苷酸,SN-38G
A phase II metabolite of irinotecan
GC49759 13C17-Mycophenolic Acid
霉酚酸-(全碳-13)
An internal standard for the quantification of mycophenolic acid
GC49755 Meclizine N-oxide
美克洛嗪N-氧化物
A metabolite of meclizine
GC49752 4,5-Desisopropylidene Topiramate
4,5-Desisopropylidene TPM
An inactive metabolite of topiramate
GC49749 6-Deoxypenciclovir
泛昔洛韦USPRCA
An inactive metabolite of famciclovir
GC49748 7-hydroxy Etodolac An inactive metabolite of etodolac