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Home >> Signaling Pathways >> Proteases >> Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for  Endogenous Metabolite

  1. Cat.No. 产品名称 Information
  2. GC63179 S-Adenosyl-L-methionine iodide

    S-腺甘-L-蛋氨酸碘盐,S-(5′-Adenosyl)-L-methionine iodide

     S-(5’-Adenosyl)-L-methionine iodide (S-Adenosyl-L-methionine iodide) 是很重要的甲基供体，存在于所有生物体中。
  3. GC63168 rel-(2R,3S)-2,3-Dihydroxysuccinic acid hydrate

    内消旋酒石酸一水

     rel-(2R,3S)-2,3-Dihydroxysuccinic acid (hydrate) 是一种内源性代谢产物。
  4. GC63166 Raffinose

    棉子糖; Melitose

     Raffinose (Melitose, Melitriose) is a complex carbohydrate, a trisaccharide composed of galactose, fructose, and glucose. It can be broken apart into galactose and sucrose via the enzyme alpha-galactosidase.
  5. GC63161 Pyrimidine

    嘧啶

     Pyrimidine 是一种内源性代谢产物。
  6. GC63152 Potassium 2-hydroxy-2-methylsuccinate

    (±)-柠苹酸钾一水合物

     Potassium 2-hydroxy-2-methylsuccinate 是一种内源性代谢产物。
  7. GC63140 Pentane-1,5-diamine dihydrochloride

    1,5-戊二胺盐酸盐

     1,5-Diaminopentane (Cadaverine) is a foul-smelling diamine formed by bacterial decarboxylation of lysine that occurs during protein hydrolysis during putrefaction of animal tissue.
  8. GC63136 Palatinose hydrate

    帕拉金糖水合物

     Isomaltulose (Palatinose) hydrate is a disaccharide carbohydrate widely used during exercise to maintain glycaemia and hydration.
  9. GC63119 NT1-O12B NT1-O12B 是一种内源性化学物质，也是一种神经递质衍生的类脂质体 (NT-lipidoid)，是几种血脑屏障 (BBB) 非渗透性物质增强脑内转运的有效载体。将 NT1-O12B 掺杂到 BBB 非渗透性脂质纳米粒 (LNPs) 中，可以使 LNPs 具有穿过 BBB 的能力。NT 类脂质体不仅有利于 BBB 的跨膜转运，而且可以将其转运到神经细胞中进行功能基因沉默或基因重组。
  10. GC63116 Normetanephrine hydrochloride

    DL-去甲变肾上腺素盐酸盐,(±)-Normetanephrine hydrochloride; DL-Normetanephrine hydrochloride; (Rac)-Normetanephrine hydrochloride

    Normetanephrine ((±)-Normetanephrine) hydrochloride 是去甲肾上腺素 (ne) 的 O-甲基化代谢产物。
  11. GC63113 N-Methylphenethylamine

    N-甲基苯乙胺

     N-Methylphenethylamine 一种天然的仲胺类神经调节剂 (neuromodulator)，可在人的尿液或植物中检测到。
  12. GC63107 NHC-triphosphate tetraammonium NHC-triphosphate tetraammonium 是 NHC 的活性胞内磷酸盐代谢物 (intracellular metabolite )，以三磷酸盐的形式存在。NHC-triphosphate tetraammonium 是病毒聚合酶 (viral polymerase) 的弱底物替代物，会被并入 HCV 复制子 RNA 中。
  13. GC63106 NHC-diphosphate triammonium NHC-triphosphate triammonium 是 NHC 的活性胞内磷酸盐代谢物 (intracellular metabolite )，以三磷酸盐的形式存在。NHC-triphosphate triammonium 是病毒聚合酶 (viral polymerase) 的弱底物替代物，会被并入 HCV 复制子 RNA 中。
  14. GC63102 neo-Inositol neo-Inositol 是肌醇的一个立体异构体，可从牛脑中分离得到。
  15. GC63093 N-Acetyloxytocin

    缩宫素杂质10

     N-Acetyloxytocin 是在大鼠垂体神经中间叶 (NIL) 中分离出来的，其存在于大鼠的几个脑区。
  16. GC63092 N-Acetyl-L-arginine dihydrate

    乙酰精氨酸,Ac-Arg-OH dihydrate

     N-Acetyl-L-arginine (Ac-Arg-OH) dihydrate is an endogenous metabolite.
  17. GC63084 Mucic acid

    粘酸

     A monosaccharide
  18. GC63071 Methyl β-D-Galactopyranoside

    甲基-Β-D-吡喃半乳糖苷

     Methyl β-D-Galactopyranoside (Methyl beta-D-galactoside, Methylgalactoside) is an endogenous metabolite.
  19. GC63042 Levothyroxine acyl glucuronide

    左甲状腺素酰葡糖苷酸,Thyroxine acyl-β-D-glucuronide

     Levothyroxine acyl glucuronide (Thyroxine Acyl-β-D-glucuronide) 是一种内源性代谢物，是甲状腺素 (T4) 的酰基葡萄糖醛酸形式。
  20. GC63040 L-Cysteic acid monohydrate

    L-磺基丙氨酸单水合物

     L-Cysteic acid monohydrate (CAM) is an active endogenous metabolite.
  21. GC63039 Lasiocarpine

    毛果天芥菜碱

     Lasiocarpine 是一种有肝毒性吡咯里西定生物碱 ( hepatotoxic PA)，在体内可引起致命的肝静脉闭塞性疾病。Lasiocarpine 只有在代谢转化为毒性中间体后才有毒性，包括 Dehydrolasiocarpine 和 N-oxide。
  22. GC63037 Lacto-N-biose I

    2-乙酰氨基-2-脱氧-3-O-(BETA-D-氟代半乳糖)-D-吡喃葡萄糖,Galβ1-3GlcNAc

     Lacto-N-biose I (Galβ1-3GlcNAc) 来自幽门螺杆菌的 α1,2-focusyltransferase 酶受体，是一种内源性代谢产物。
  23. GC63024 Isethionic acid sodium salt

    羟乙基磺酸钠,Sodium 1-hydroxy-2-ethanesulfonate; Sodium 2-hydroxy-1-ethanesulfonate; Sodium 2-hydroxyethanesulfonate

     Isethionic acid sodium salt is an amphoteric detergent used in detergent bar soaps.
  24. GC62993 Glycocholic acid hydrate

    甘氨胆酸

     Glycocholic acid (Cholylglycine, Glycocholate) is a natural secondary bile acid involved in the emulsification of fats.
  25. GC62962 Ethyl nonanoate

    壬酸乙酯

     Ethyl nonanoate 是一种在烈酒中含量丰富的酯，其存在通常与令人愉悦的果味酒精饮料有关。Ethyl nonanoate 是一种内源性代谢产物。
  26. GC62961 Estriol 3-glucuronide

    雌三醇3-葡萄糖醛酸苷

     Estriol-3-glucuronide 存在于正常妊娠羊水中和自然发生的尿液中。
  27. GC62954 Enterostatin(human,mouse,rat) TFA Enterostatin (human,mouse,rat) TFA 是一种五肽，主要由胰前脂酶在肠道中裂解而形成。Enterostatin 可以选择性地降低脂肪摄取量、体重和体脂。
  28. GC62935 Dihydroxyfumaric acid hydrate

    二羟基富马酸水合物

     Dihydroxyfumaric acid hydrate (DHF) is an endogenous metabolite. The diester derivative of dihydroxyfumaric acid hydrate (DHF) has been used exclusively as an electrophile in organic synthesis.
  29. GC62931 Dichloroiodomethane

    二氯碘甲烷

    Dichloroiodomethane 是可存在于人体中的天然产物。
  30. GC62930 Diadenosine pentaphosphate pentasodium

    P1,P5-二(腺苷5′)五磷酸五钠盐

     Diadenosine pentaphosphate pentasodium 是一种内源性血管活性嘌呤二核苷酸，可从血小板中分离出来。Diadenosine polyphosphates (ApnA, n=2-7) 已被确定为分泌小泡的成分，如血小板、嗜铬细胞、Torpedo 突出末端和脑突触体。
  31. GC62929 Diadenosine pentaphosphate pentaammonium

    P1,P5-二(腺苷-5ˊ)五磷酸五铵盐

     Diadenosine pentaphosphate pentaammonium 是一种内源性血管活性嘌呤二核苷酸，可从血小板中分离出来。Diadenosine polyphosphates (ApnA, n=2-7) 已被确定为分泌小泡的成分，如血小板、嗜铬细胞、Torpedo 突出末端和脑突触体。
  32. GC62928 D-Glucaric acid potassium

    D-葡萄糖二酸单钾盐

     D-Saccharic acid potassium salt (D-Glucaric acid potassium, Potassium bisaccharate) is an endogenous metabolite.
  33. GC62921 D-Allose

    D-阿洛糖

     D-Allose 是一种内源性代谢产物。
  34. GC62920 D-(-)-Lactic acid sodium

    D-乳酸钠,(R)-2-Hydroxypropionic acid sodium

     D-(-)-Lactic acid ((R)-2-Hydroxypropionic acid ) sodium 是一种内源性代谢产物。
  35. GC62919 D-Glucosamic acid

    D-氨基葡萄糖酸杂质F

     D-?Glucosamic acid 是一种内源性代谢产物。
  36. GC62906 Cortisol sulfate

    皮质醇21-硫酸; Cortisol 21-sulfate

    Cortisol sulfate (Cortisol 21-sulfate) 是皮质醇 的一种代谢物。Cortisol sulfate 是细胞内运皮质激素蛋白的一种特异性配体。
  37. GC62896 Cholesterol glucuronide Cholesterol glucuronide 是一种由 UDP 葡萄糖醛酸转移酶在肝脏中产生的脂质的内源性代谢产物。
  38. GC62884 Calcium L-Threonate

    L-苏糖酸钙

     L-Threonic acid Calcium Salt (Calcium threonate) is a calcium salt of threnoic acid. L-Threonic acid is a metabolite of ascorbic acid (vitamin C).
  39. GC62883 Calcium 2-hydroxy-4-(methylthio)butanoate

    羟基蛋氨酸钙

     Calcium 2-hydroxy-4-(methylthio)butanoate is an active endogenous metabolite.
  40. GC62828 Adenine monohydrochloride hemihydrate

    腺嘌呤盐酸盐

     Adenine monohydrochloride hemihydrate 是一种内源性代谢产物。
  41. GC62817 7-Methylguanosine 5’-diphosphate sodium

    7-Methyl-GDP sodium; m7GDP sodium

     7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium，一种 cap 类似物，可以用来合成 mRNA cap 类似物。
  42. GC62816 6-Hydroxypyridin-2(1H)-one hydrochloride

    2,6-二羟基吡啶盐酸盐

     6-Hydroxypyridin-2(1H)-one hydrochloride 是一种内源性代谢产物。
  43. GC62814 5-Phenylvaleric acid

    5-苯基戊酸,5-Phenylpentanoic acid

     5-Phenylvaleric acid (Benzenepentanoic acid, Phenylpentanoic acid, Phenylvaleric Acid) is a Pentanoic acid of bacterial origin, occasionally found in human biofluids.
  44. GC62811 5-Methoxy-5-oxopentanoic acid

    戊二酸单甲酯

     Monomethyl glutaric acid (5-Methoxy-5-oxopentanoic acid) is a dicarboxylic acid monoester and has a role as a human urinary metabolite.
  45. GC62810 5-Hydroxytryptamine creatinine sulfate monohydrate

    5-五羟色胺肌酸酐

     Serotonin (5-Hydroxytryptamine) creatinine sulfate monohydrate is an active endogenous metabolite.
  46. GC62803 4-Formylaminoantipyrine

    4-甲酰氨基安替比林

     4-Formylaminoantipyrine 是氨基苯那酮的排泄代谢物 (metabolite)。Aminophenazone 是一种具有镇痛、抗炎、解热作用的吡唑啉酮。
  47. GC62800 4,4’-Disulfanediylbis(2-aminobutanoic acid)

    高胱氨酸

     An oxidized dimeric form of homocysteine
  48. GC62798 3-Phenylbutyric acid

    3-苯基丁酸

     3-Phenylbutyric acid 通过苯环的初始氧化和侧链的初始氧化而代谢，可用于从堆肥土壤中分离出紫红红球菌 (Rhodococcus rhodochrous) PB1。
  49. GC62797 3-Oxo-4,6-choladien-24-oic acid 3-Oxo-4,6-choladien-24-oic acid 是一种内源性代谢物。3-Oxo-4,6-choladien-24-oic acid 存在于肝胆疾病患者的尿液中。
  50. GC62796 3-Methylvaleric Acid

    3-甲基戊酸

     3-Methylvaleric acid is a flavouring ingredient.
  51. GC62795 3-Methylhistamine dihydrochloride

    5-氨乙基-1-甲基咪唑二盐酸盐

     3-Methylhistamine dihydrochloride 是一种内源性代谢产物。

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