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Home >> Signaling Pathways >> Stem Cell

Stem Cell(干细胞)

Cat.No. 产品名称 Information
GC13576 TC-G 24 TC-G 24 (Compound 24) 是一种有效的、选择性的糖原合酶激酶-3β (GSK-3β) 抑制剂，IC50 为 17.1 nM。
GC14306 3F8 3F8 是一种有效且选择性的 GSK-3β 抑制剂，可用作 GSK3 相关疾病的新试剂和潜在治疗候选物。
GC10854 IDE 2 An inducer of definitive endoderm from embryonic stem cells
GC14233 BIO-acetoxime
6-溴靛玉红-3'-丙酮肟,BIA
A potent, selective inhibitor of GSK3α/β
GC11627 TCS 2002 TCS 2002 (Compound 9b) 是一种高选择性、口服生物利用度和有效的 GSK-3β；抑制剂，IC50 为 35 nM。
GC13582 KHS 101 hydrochloride neuronal differentiation inducer
GC10910 IQ 1 A stem cell pluripotency factor
GC12192 MRT 10 An antagonist of the Smo receptor
GC10336 A 1070722 A GSK3β inhibitor
GC15123 IDE 1 An inducer of definitive endoderm from embryonic stem cells
GC14299 exo-IWR 1 Control for IWR-1-endo
GC13301 TCS 2210 A small molecule inducer of neuronal differentiation
GC17840 Cardiogenol C hydrochloride
2-[[2-[(4-甲氧基苯基)氨基]-4-嘧啶基]氨基]乙醇盐酸盐
Cardiogenol C hydrochloride 是一种有效的细胞渗透性嘧啶诱导剂，可促进 ESC 分化为心肌细胞 (EC50=100 nM)。
GC11454 Neurodazine Small molecule inducer of neuronal differentiation
GC16711 PNU 74654 An inhibitor of β-catenin/Wnt signaling
GC17251 QS 11 An ARFGAP inhibitor
GC12661 Indirubin-3'-oxime
靛玉红-3'-单肟,IDR3O; I3O
Inhibitor of GSK3β and cyclin-dependent kinases
GC14899 AMG 548 An inhibitor of p38α MAPK
GC11515 TCS 184
TCS183对照肽
TCS 184 是一个多肽片段。
GC10573 L803-mts Selective peptide inhibitor of glycogen synthase kinase-3 (GSK-3)
GC10440 TCS 183 competitive inhibitor of GSK-3β (Ser9) phosphorylation
GC17457 FRATide
GSK-3 inhibitor
GC15422 20(S)-Hydroxycholesterol
20Α-羟基胆固醇,20α-hydroxy Cholesterol
An allosteric Smo agonist
GC15284 U 18666A U18666A是一种具有细胞渗透性和两亲性的小分子，可以抑制3β羟基甾醇-Δ（24）还原酶（DHCR24）活性, 从而阻止胆固醇从晚期核内体和溶酶体外流[2]。
GC14182 Kenpaullone
克莱拉尼,9-Bromopaullone; NSC-664704
A inhibitor of cyclin-dependent kinase and GSK3β
GC16640 iCRT 14 An inhibitor of β-catenin-responsive transcription
GC11484 CPI-169 S-enantiomer EZH2 inhibitor
GC12146 CPI-169 R-enantiomer EZH2 inhibitor
GC16599 CPI-169 A selective EZH2 inhibitor
GC13907 1-Azakenpaullone
1-氮杂坎帕罗酮,1-Akp
A potent inhibitor of GSK3β
GC11115 Pamidronate
帕米膦酸
An FPP synthase inhibitor that inhibits bone resorption
GC10151 OAC1
N-1H-吡咯并[2,3-C]吡啶-5-基苯甲酰胺
An Oct4-activating compound
GC11775 Nefopam HCl
盐酸奈福泮; Fenazoxine hydrochloride
Nefopam HCl (Fenazoxine hydrochloride) 是一种中枢作用但非阿片类镇痛药，用于缓解中度至重度疼痛。
GC10950 IWR-1-endo
endo-IWR 1; IWR-1-endo
IWR-1-endo 是一种有效的 Wnt 反应抑制剂，可阻断基于细胞的 Wnt/β-catenin 通路报告基因反应，IC₅₀ 值为 180 nM。
GC14896 Halcinonide
氯氟舒松; SQ-18566
A synthetic glucocorticoid
GC14987 GSK-3 Inhibitor IX (BIO)
(2'Z,3'E)-6-溴靛玉红-3'-肟,GSK-3 Inhibitor IX
A potent, selective, and reversible GSK3 inhibitor
GC13655 LDE225 (NVP-LDE225,Erismodegib)
索尼吉布,Erismodegib; LDE225; NVP-LDE225
LDE225 (NVP-LDE225,Erismodegib) (Erismodegib) 是一种有效的选择性 Smo 拮抗剂，在结合试验中对小鼠和人 Smo 的 IC50 分别为 1.3 nM 和 2.5 nM。
GC17466 LH846 A selective inhibitor of CK1δ
GC14756 EI1
6-氰基-N-[(1,2-二氢-4,6-二甲基-2-氧代-3-吡啶基)甲基]-1-(1-乙基丙基)-1H-吲哚-4-甲酰胺,KB-145943
A selective inhibitor of EZH2
GC14465 Tideglusib
4-苄基-2-(萘-1-基)-[1,2,4]噻二唑烷-3,5-二酮,NP031112
A neuroactive thiadiazolidinone
GC16568 AZD1080 A potent inhibitor of GSK3α and GSK3β
GC14840 TDZD-8
GSK-3β Inhibitor I; NP 01139
A selective inhibitor of GSK3β
GC17868 TWS119 A GSK3β inhibitor
GC11424 Valproic acid
丙戊酸; VPA; 2-Propylpentanoic Acid
A class I HDAC inhibitor
GC17690 Cromolyn sodium
色甘酸钠; Disodium Cromoglycate; FPL-670
A mast cell stabilizer
GC16230 PF-04449913
格拉斯吉布,PF-04449913
A Smo antagonist
GC12392 LGK-974
2',3-二甲基-N-[5-(2-吡嗪基)-2-吡啶基]-[2,4'-联吡啶]-5-乙酰胺,WNT974
A potent, bioavailable inhibitor of PORCN
GC17708 IWP-L6
Porcn Inhibitor III
A potent inhibitor of Porcupine
GC16701 SKI II
鞘氨醇激酶抑制剂
An SPHK1 inhibitor
GC14736 AZD2858 A GSK3β inhibitor