Stem Cell(干细胞)
- CK1(5)
- EZH2(10)
- GSK-3(68)
- HSC(6)
- iPSC(6)
- Hedgehog(43)
- Notch(37)
- Smoothened(35)
- Wnt/β-catenin(139)
- Hippo Signaling(6)
- Cancer stem cell(28)
- MST1/2(1)
- ESC(1)
- Oct3/4(5)
- Porcupine(6)
- YAP(34)
- Casein Kinase(47)
- Cat.No. 产品名称 Information
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GC12192
MRT 10
An antagonist of the Smo receptor
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GC10336
A 1070722
A GSK3β inhibitor
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GC15123
IDE 1
An inducer of definitive endoderm from embryonic stem cells
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GC14299
exo-IWR 1
Control for IWR-1-endo
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GC13301
TCS 2210
A small molecule inducer of neuronal differentiation
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GC17840
Cardiogenol C hydrochloride
2-[[2-[(4-甲氧基苯基)氨基]-4-嘧啶基]氨基]乙醇盐酸盐
Cardiogenol C hydrochloride 是一种有效的细胞渗透性嘧啶诱导剂，可促进 ESC 分化为心肌细胞 (EC50=100 nM)。
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GC11454
Neurodazine
Small molecule inducer of neuronal differentiation
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GC16711
PNU 74654
An inhibitor of β-catenin/Wnt signaling
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GC17251
QS 11
An ARFGAP inhibitor
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GC12661
Indirubin-3'-oxime
靛玉红-3'-单肟,IDR3O; I3O
Inhibitor of GSK3β and cyclin-dependent kinases
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GC14899
AMG 548
An inhibitor of p38α MAPK
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GC11515
TCS 184
TCS183对照肽
TCS 184 是一个多肽片段。
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GC10573
L803-mts
Selective peptide inhibitor of glycogen synthase kinase-3 (GSK-3)
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GC10440
TCS 183
competitive inhibitor of GSK-3β (Ser9) phosphorylation
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GC17457
FRATide
GSK-3 inhibitor
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GC15422
20(S)-Hydroxycholesterol
20Α-羟基胆固醇,20α-hydroxy Cholesterol
An allosteric Smo agonist
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GC15284
U 18666A
U18666A是一种具有细胞渗透性和两亲性的小分子，可以抑制3β羟基甾醇-Δ（24）还原酶 （DHCR24）活性, 从而阻止胆固醇从晚期核内体和溶酶体外流[2]。
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GC14182
Kenpaullone
克莱拉尼,9-Bromopaullone; NSC-664704
A inhibitor of cyclin-dependent kinase and GSK3β
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GC16640
iCRT 14
An inhibitor of β-catenin-responsive transcription
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GC11484
CPI-169 S-enantiomer
EZH2 inhibitor
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GC12146
CPI-169 R-enantiomer
EZH2 inhibitor
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GC16599
CPI-169
A selective EZH2 inhibitor
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GC13907
1-Azakenpaullone
1-氮杂坎帕罗酮,1-Akp
A potent inhibitor of GSK3β
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GC11115
Pamidronate
帕米膦酸
An FPP synthase inhibitor that inhibits bone resorption
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GC10151
OAC1
N-1H-吡咯并[2,3-C]吡啶-5-基苯甲酰胺
An Oct4-activating compound
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GC11775
Nefopam HCl
盐酸奈福泮; Fenazoxine hydrochloride
Nefopam HCl (Fenazoxine hydrochloride) 是一种中枢作用但非阿片类镇痛药，用于缓解中度至重度疼痛。
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GC10950
IWR-1-endo
endo-IWR 1; IWR-1-endo
IWR-1-endo 是一种有效的 Wnt 反应抑制剂，可阻断基于细胞的 Wnt/β-catenin 通路报告基因反应，IC50 值为 180 nM。
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GC14896
Halcinonide
氯氟舒松; SQ-18566
A synthetic glucocorticoid
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GC14987
GSK-3 Inhibitor IX (BIO)
(2'Z,3'E)-6-溴靛玉红-3'-肟,GSK-3 Inhibitor IX
A potent, selective, and reversible GSK3 inhibitor
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GC13655
LDE225 (NVP-LDE225,Erismodegib)
索尼吉布,Erismodegib; LDE225; NVP-LDE225
LDE225 (NVP-LDE225,Erismodegib) (Erismodegib) 是一种有效的选择性 Smo 拮抗剂，在结合试验中对小鼠和人 Smo 的 IC50 分别为 1.3 nM 和 2.5 nM。
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GC17466
LH846
A selective inhibitor of CK1δ
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GC14756
EI1
6-氰基-N-[(1,2-二氢-4,6-二甲基-2-氧代-3-吡啶基)甲基]-1-(1-乙基丙基)-1H-吲哚-4-甲酰胺,KB-145943
A selective inhibitor of EZH2
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GC14465
Tideglusib
4-苄基-2-(萘-1-基)-[1,2,4]噻二唑烷-3,5-二酮,NP031112
A neuroactive thiadiazolidinone
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GC16568
AZD1080
A potent inhibitor of GSK3α and GSK3β
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GC14840
TDZD-8
GSK-3β Inhibitor I; NP 01139
A selective inhibitor of GSK3β
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GC17868
TWS119
A GSK3β inhibitor
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GC11424
Valproic acid
丙戊酸; VPA; 2-Propylpentanoic Acid
A class I HDAC inhibitor
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GC17690
Cromolyn sodium
色甘酸钠; Disodium Cromoglycate; FPL-670
A mast cell stabilizer
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GC16230
PF-04449913
格拉斯吉布,PF-04449913
A Smo antagonist
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GC12392
LGK-974
2',3-二甲基-N-[5-(2-吡嗪基)-2-吡啶基]-[2,4'-联吡啶]-5-乙酰胺,WNT974
LGK-974是一种高效且特异的Porcupine（PORCN）抑制剂。
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GC17708
IWP-L6
Porcn Inhibitor III
A potent inhibitor of Porcupine
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GC16701
SKI II
鞘氨醇激酶抑制剂
An SPHK1 inhibitor
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GC14736
AZD2858
A GSK3β inhibitor
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GC10211
FLI-06
1,4,5,6,7,8-六氢-2,7,7-三甲基-4-(4-硝基苯基)-5-氧代-3-喹啉羧酸环己基酯
A Notch inhibitor
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GC13658
Wnt-C59
PORCN酶活性和WNT抑制剂(WNT-C59),C59
Wnt-C59是Mboat（膜结合的O-酰脱糖酶）家族成员Porcupine（Porcn）的高度有效抑制剂，IC50值为74pM，能够抑制Wnt信号传导。
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GC15889
SANT-1
An antagonist of Smoothened
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GC12429
AY 9944 dihydrochloride
A cholesterol synthesis inhibitor
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GC14715
AZ 12080282 dihydrochloride
刺猬抑制剂
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GC11111
Jervine
蒜黎芦碱; 11-Ketocyclopamine
An inhibitor of the hedgehog signaling pathway
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GC11476
Ciliobrevin A
HPI-4
A hedgehog pathway inhibitor