EZH2(zeste 同源物 2增强子)

EZH2 (enhancer of zeste homolog 2) is a polycomb group protein and histone methyltrasferase that associated with transcriptional repression. It catalyzes trimethylation of H3K27me3 (histone H3 lysine 27) as a catalytic subunit of PRC2 (polycomb repressive complex 2).

Products for EZH2

Cat.No. 产品名称 Information
GC11414 GSK503 A potent, selective EZH2 inhibitor
GC11484 CPI-169 S-enantiomer EZH2 inhibitor
GC12146 CPI-169 R-enantiomer EZH2 inhibitor
GC16599 CPI-169 A selective EZH2 inhibitor
GC14756 EI1
6-氰基-N-[(1,2-二氢-4,6-二甲基-2-氧代-3-吡啶基)甲基]-1-(1-乙基丙基)-1H-吲哚-4-甲酰胺,KB-145943
A selective inhibitor of EZH2
GC17534 GSK343
GSK-343;GSK 343
A selective, cell-permeable EZH2 inhibitor
GC15783 GSK126
EZH2 inhibitor;GSK-126;GSK 126
GSK126(GSK2816126A, GSK2816126)是一种高选择性EZH2甲基转移酶抑制剂，在体外的IC₅₀为12.6~17.4nM；在体内的IC₅₀为9.9nM。
GC13878 EPZ005687
EPZ 005687,EPZ-005687
A potent, selective inhibitor of EZH2
GC17907 3-Deazaneplanocin A (DZNep) hydrochloride
3-去氮腺嘌呤A盐酸盐; DZNep hydrochloride; NSC 617989 hydrochloride; 3-Deazaneplanocin hydrochloride
3-Deazaneplanocin A (DZNep) hydrochloride 是一种腺苷类似物，是一种竞争性 S-腺苷高半胱氨酸水解酶抑制剂，在无细胞试验中的 Ki 为 50 pM。
GC13145 3-Deazaneplanocin,DZNep
3-去氮腺嘌呤A; DZNep; 3-Deazaneplanocin

An inhibitor of lysine methyltransferase EZH2