Tyrosine Kinase(酪氨酸激酶)

Cat.No. 产品名称 Information

GC44806 Ras Inhibitory Peptide

Sos SH3 Domain Inhibitor

An inhibitor of activation of Ras

GC44613 PF-6274484 An EGFR inhibitor

GC44605 Petunidin (chloride)

矮牵牛素PT,Petunidol

An O-methylated anthocyanidin

GC44585 PD 174265 A potent, cell-permeable inhibitor of EGFR kinase

GC44583 PD 089828

EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor

An inhibitor of EGFR, PDGFβ, FGF, and c-Src

GC44491 O-Desmethyl Gefitinib

O-去甲基吉非替尼

A major active metabolite of gefitinib

GC44475 NVP-BEZ235 (hydrochloride)

Dactolisib

Dual inhibitor of PI3K and mTOR

GC44474 NVP-AEW541 (hydrochloride) An IGF-1R inhibitor

GC44358 Nebivolol O-β-D-Glucuronide An active metabolite of nebivolol

GC44290 NAADP (sodium salt)

Nicotinic acid adenine dinucleotide phosphate

A secondary messenger that induces calcium mobilization

GC44263 Myrtillin

氯化飞燕草素葡萄糖苷; Delphinidin 3-O-glucoside chloride; Delphinidin 3-O-β-glucoside chloride

桃金娘苷（Delphinidin 3-o-glucoside）是一种花青素单体，主要分布于各种植物中，可用高效液相色谱法（HPLC）质谱法（Mass）和核磁共振法进行定性和定量分析(NMR)。

GC44085 L-Sulforaphene

莱菔素

A natural isothiocyanate

GC44047 LDN-192960 (hydrochloride) An inhibitor of haspin and DYRK2

GC43885 Hypothemycin

寄端霉素

A resorcylic acid lactone polyketide with diverse biological activities

GC43795 GTP 14564 An inhibitor of class III receptor tyrosine kinases

GC43732 Ganglioside GM3 Mixture (sodium salt)

单唾液神经节苷酯GM3; Hematoside; Sialosyllactosylceramide

A mixture of ganglioside G_M3

GC43676 FLT3 Inhibitor III

Fms-like Tyrosine Kinase Inhibitor III

A potent, highly selective inhibitor of FLT3

GC43503 DMHAPC-Chol

Dimethyl Hydroxyethyl Aminopropane Carbamoyl Cholesterol Iodide

A cationic cholesterol

GC43433 D-Glucosamine-6-sulfate

D-氨基葡萄糖-6-硫酸盐

A glycosaminoglycan

GC43268 Cinnamtannin B-1

肉桂单宁B-1

A polyphenol antioxidant

GC43198 CAY10717 A multi-targeted kinase inhibitor

GC42972 Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)

Brain-derived aFGF (1-11)

A peptide fragment

GC42887 Axitinib Sulfoxide

阿西替尼杂质A

A major inactive metabolite of axitinib

GC42884 Avitinib

艾维替尼,Abivertinib; AC0010

A selective inhibitor of mutant EGFR

GC42616 7-oxo Staurosporine

BMY 41950, RK-1409

An antibiotic with diverse biological activities

GC42409 4-hydroxy Nebivolol (hydrochloride) A major metabolite of nebivolol

GC42026 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC

1-十六酰-SN-丙三醇-磷酸胆碱

A product of PLA₂-mediated hydrolysis of phosphatidylcholine

GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol

(±)214,15EG

A cytochrome P450 metabolite of 2-AG

GC41653 (±)16(17)-DiHDPA An epoxygenase metabolite of DHA

GC41631 BPIQ-I

PD 159121

A potent EGFR inhibitor

GC41626 Sappanone A Sappanone A是一种具有较强抗氧化和抗炎活性的同型异黄酮。

GC41577 Tephrosin (synthetic)

灰叶草素; Deguelinol I; Hydroxydeguelin

An antineoplastic and piscicidal rotenoid

GC41467 Reveromycin D

雷弗霉素D

A bacterial metabolite

GC41183 α-Carotene

α-胡萝卜素

A precursor of vitamin A

GC40915 PKI-166 An inhibitor of EGFR

GC40865 LYG-202 A synthetic flavonoid with anticancer and anti-angiogenic activities

GC40755 SU 5214

SU4949

A 3-heteroaryl-2-indoline

GC40623 NBI 31772 A nonpeptide ligand that releases IGF-1 from IGFBP

GC40567 N-(p-Coumaroyl) Serotonin

N-(P-香豆酰)-羟色胺

A natural antioxidant with anti-atherosclerotic actions

GC40555 Tiopronin

BRN 1859822, (±)-Tiopronin

Tiopronin is an antioxidant that has diverse biological activities.

GC40547 RK-20448 A multi-kinase inhibitor

GC19534 Ramucirumab

雷莫芦单抗

Ramucirumab 是一种人 VEGFR-2 拮抗剂，用于治疗实体瘤。 Ramucirumab 是一种重组人免疫球蛋白 G1 单克隆抗体，可与 VEGFR-2 的细胞外结合结构域结合并阻止 VEGFR 配体:VEGF-A、VEGF-C 和 VEGF-D 的结合。 Ramucirumab 也是一种血管生成抑制剂。

GC34847 TX1-85-1 An ErbB3 inhibitor

GC34811 SRI 31215 TFA SRI31215(TFA)是一种matriptase、hepsin、肝细胞生长因子激活剂(HGFA)的三重抑制剂，IC50值分别为0.69μM、0.65μM、0.3μM，SRI31215通过阻断pro-HGF的活化，从而模拟了HAI-1/2的活性。

GC34809 SPP-86 SPP-86, a potent and selective cell permeable inhibitor of rearranged during transfection (RET) tyrosine kinase with an IC50 of 8 nM, inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells.

GC34710 PF-06747711 PF-06747711是一种有效、选择性、可口服的视黄酸受体相关孤儿受体C2(RORC2或RORγt)的反向激动剂，IC50值为4.1nM。具有抗皮肤炎的功效。

GC34708 Pexidartinib hydrochloride

培西达替尼盐酸盐,PLX-3397 hydrochloride

A multi-targeted receptor tyrosine kinase inhibitor

GC34529 c-Fms-IN-1 c-Fms-IN-1是一种FMS激酶抑制剂，IC50值为0.0008μM。

GC34528 cFMS Receptor Inhibitor II cFMSReceptorInhibitorII是一种CSF1R激酶抑制剂。CSF-1是一种细胞因子。

GC34509 BT-13 BT-13是有效的、胶质细胞源性神经营养因子(GDNF)受体RET的选择性激动剂(独立于GDNF配体发挥作用)，促进体外感觉神经元神经突生长，减轻大鼠神经病变的发生。