Tyrosine Kinase(酪氨酸激酶)
- Bcr-Abl(64)
- Ack1(2)
- Axl(6)
- ALK(54)
- BMX Kinase(3)
- Broad Spectrum Protein Kinase Inhibitor(10)
- c-FMS(35)
- c-Kit(55)
- c-MET(82)
- c-RET(7)
- CSF-1R(3)
- DDR1/DDR2 Receptor(1)
- EGFR(225)
- EphB4(1)
- FAK(33)
- FGFR(94)
- FLT3(82)
- HER2(15)
- IGF1R(33)
- Insulin Receptor(42)
- IRAK(28)
- ITK(10)
- Lck(1)
- LRRK2(21)
- PDGFR(104)
- PTKs/RTKs(3)
- Pyk2(6)
- ROR(38)
- Spleen Tyrosine Kinase (Syk)(32)
- Src(95)
- Tie-2 (4)
- Trk(40)
- VEGFR(181)
- Discoidin Domain Receptor(15)
- DYRK(28)
- Ephrin Receptor(12)
- RET(28)
- ROS(14)
- TAM Receptor(28)
- IGFBR(1)
- Others(55)
- Cat.No. 产品名称 Information
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GC14592
KW 2449
[4-[2-(1H-吲唑-3-基)乙烯基]苯基]-1-哌嗪基甲酮
A multi-kinase inhibitor
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GC10638
AT9283
A broad spectrum kinase inhibitor
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GC15217
Danusertib (PHA-739358)
达鲁舍替,5-Amido-pyrrolopyrazole 9d
A pan-Aurora kinase and Abl inhibitor
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GC16519
ENMD-2076
6-(4-甲基-1-哌嗪基)-N-(5-甲基-1H-吡唑-3-基)-2-[(1E)-2-苯乙烯基]-4-嘧啶胺
A multi-kinase inhibitor
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GC12145
ENMD-2076 L-(+)-Tartaric acid
ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。
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GC15589
WHI-P154
2-溴-4-(6,7-二甲氧基喹唑啉-4-基氨基)苯酚
A JAK3 inhibitor
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GC13848
LY2784544
Gandotinib
Potent inhibitor of JAK2
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GC10035
TG101209
N-(1,1-二甲基乙基)-3-[[5-甲基-2-[[4-(4-甲基-1-哌嗪基)苯基]氨基]-4-嘧啶基]氨基]苯磺酰胺,TG-101209
An inhibitor of JAK2, FLT3, RET, and JAK3
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GC16008
CUDC-101
7-[[4-(3-乙炔基苯基氨基)-7-甲氧基喹唑啉-6-基]氧基]-N-羟基庚酰胺,CUDC101, CUDC 101
A multi-target inhibitor of HDACs, EGFR, and HER2
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GC16327
Pazopanib (GW-786034)
帕唑帕尼; GW786034
A multi-kinase inhibitor
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GC14729
(R)-Crizotinib
克唑替尼; PF-02341066
A c-MET and ALK receptor tyrosine kinase inhibitor
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GC15568
Dasatinib (BMS-354825)
达沙替尼; BMS-354825
An inhibitor of Abl and Src
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GC10055
BGJ398
FGFR抑制剂(NVP-BGJ398),BGJ398,BGJ-398,Infigratinib
An FGFR inhibitor
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GC17369
Sorafenib
索拉非尼; Bay 43-9006
索拉非尼Sorafenib是Raf-1和B-Raf的多激酶抑制剂，IC50分别为6 nM和22 nM;Sorafenib对VEGFR-2 VEGFR-3 PDGFR-β Flt-3和c-KIT也有抑制作用，IC50值分别为90 nM、20 nM、57 nM、59 nM和68 nM;索拉非尼能诱导自噬细胞凋亡和激活铁死亡，并具有抗肿瘤活性。
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GC15983
PD 153035 hydrochloride
ZM252868,PD153035 HCL
A highly potent EGFR inhibitor
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GC12837
Compound 56
N-(3-溴苯基)-6,7-二乙氧基-4-喹唑啉胺
A potent EGFR inhibitor
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GN10503
Piceatannol
白皮杉醇; Astringenin; trans-Piceatannol
Piceatannol(3,3 '，4,5 ' -反式三羟基二苯乙烯)是天然存在的白藜芦醇羟基化类似物。
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GN10784
Rhoifolin
野漆树苷
A flavonoid glycoside with diverse biological activities
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GN10633
Scutellarein
野黄芩素; 6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone
A natural flavone with diverse biological activities
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GN10497
Kaempferitrin
山奈苷; Lespedin; Lespenephryl
A flavonoid glycoside with diverse biological activities
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GN10540
Fumalic acid
天然阿魏酸, 来源于川芎, Coniferic acid
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.
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GN10327
Chrysophanol
大黄酚; Chrysophanic acid
An anthraquinone with diverse biological activities
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GN10737
Tanshinone IIA
丹参酮IIA; Dan Shen ketone
Tanshinone IIA 是一种从丹参中分离出来的主要丹参酮，常用于心血管疾病和癌症的研究。
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GN10603
Sennoside B
番泻苷 B
A glycoside with laxative and gastroprotective activities
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GN10527
Formononetin
刺芒柄花素: Biochanin B: Flavosil; Formononetol
Formononetin是一种强效的FGFR2抑制剂，其IC50值约为4.31μM。Formononetin能有效抑制血管生成和肿瘤生长。
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GN10156
Ginsenoside Rb1
人参皂苷 Rb1; Gypenoside III
A triterpene saponin with diverse biological activities
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GN10336
Daphnetin
瑞香素; 7,8-Dihydroxycoumarin
A coumarin derivative with diverse biological activities
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GN10325
Nobiletin
川陈皮素
A flavonoid with diverse biological activities
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GC15299
Staurosporine(CGP 41251)
星形孢菌素; Antibiotic AM-2282; STS; AM-2282
Staurosporin 是一种小激酶抑制剂，是一种从细菌 Streptomyces staurosporeus 中提取的生物碱。