Axl(通路)

Axl is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm and takes part in the stimulation of cell proliferation.

Products for Axl

Cat.No. 产品名称 Information
GC14218 TP-0903
TP-0903
An Axl kinase inhibitor
GC14241 LDC1267 A TAM family kinase inhibitor
GC13500 UNC2881 A Mer kinase inhibitor
GC17618 R428
R-428;R 428;BGB324
R428作为一种Axl抑制剂,在纳摩尔浓度下阻断Axl在其C端对接位点Tyr821上的自动磷酸化。
GC14214 BMS-777607
N-[4-[(2-氨基-3-氯吡啶-4-基)氧基]-3-氟苯基]-4-乙氧基-1-(4-氟苯基)-2-氧代-1,2-二氢吡啶-3-甲酰胺,BMS 817378
BMS-777607 是一种泛 TAM 抑制剂，对不同类型的癌症显示出抗肿瘤活性。
GC15779 Cabozantinib (XL184, BMS-907351)
卡博替尼; XL184; BMS-907351
Cabozantinib (XL184,BMS-907351) 是一种新型 MET 和 VEGFR2 抑制剂，可同时抑制转移、血管生成和肿瘤生长。