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Home >> Signaling Pathways >> Tyrosine Kinase >> BMX Kinase

BMX Kinase(BMX激酶)

Bmx kinase is a member of Tec kinase family. It is involved in different signaling pathways and controls differential and tumorigenicity in several cancer types.

Products for  BMX Kinase

  1. Cat.No. 产品名称 Information
  2. GC35684 CHMFL-EGFR-202 CHMFL-EGFR-202 是一种有效、不可逆的表皮生长因子受体 (EGFR) 突变型激酶抑制剂， 对 耐药突变型 EGFR T790M 和 WT EGFR 激酶作用的 IC50 值分别为 5.3 nM 和 8.3 nM。在细胞中，CHMFL-EGFR-202 对 EGFR L858R/T790M 的选择性是 EGFR 野生型的 10 倍。CHMFL-EGFR-202 以 “DFG-in-C-helix-out” 的不活跃结合构象形式共价结合 EGFR，对 EGFR 突变体驱动的非小细胞肺癌 (NSCLC) 细胞株具有较强的抗增殖作用。
  3. GC33020 CHMFL-BMX-078 (CHMFL-BMX 078)

    CHMFL-BMX 078

     An irreversible BMX inhibitor
  4. GC11063 BMX-IN-1

    N-[2-甲基-5-[9-[4-[(甲基磺酰基)氨基]苯基]-2-氧代苯并[H]-1,6-萘啶-1(2H)-基]苯基]-2-丙烯酰胺,BMX kinase inhibitor

     A selective BMX and BTK inhibitor

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