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Home >> Signaling Pathways >> Ubiquitination/ Proteasome

Ubiquitination/ Proteasome(泛素化/蛋白酶体)

  1. Cat.No. 产品名称 Information
  2. GC10326 Erythromycin Ethylsuccinate

    琥乙红霉素; Erythromycin ethyl succinate; EES

     Erythromycin Ethylsuccinate 是一种可用于治疗多种细菌感染的抗生素，其抗菌谱与青霉素相似或略宽。
  3. GC12846 Elaiophylin

    洋橄榄叶素,Azalomycin B; Gopalamicin; Efomycin E

     A macrodiolide antibiotic
  4. GC13502 Cysteamine HCl

    半胱胺盐酸盐; 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride

     A radioprotective aminothiol
  5. GC16332 Colistin Sulfate

    硫酸粘杆菌素; Polymyxin E sulfate

     An antibiotic
  6. GC15810 Clinofibrate

    克利贝特,S-8527

     A hypolipidemic agent
  7. GC14892 Clemastine Fumarate

    富马酸氯马斯汀; HS-592 fumarate; Meclastine fumarate

     A histamine H1 receptor antagonist
  8. GC14421 CFTRinh-172

    CFTR(inh)172, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor 172

     A potent CFTR channel blocker
  9. GC17341 Carprofen

    卡洛芬

     An NSAID used in animals
  10. GC12733 C646 C646是一种有效的选择性p300/CBP组蛋白乙酰转移酶抑制剂(Ki 400 nM),已被证明具有多效性,包括神经保护、抗癌和抗上皮间质转化(anti-EMT)作用。
  11. GC17683 Brefeldin A

    布雷非德菌素 A; BFA; Cyanein; Decumbin

     Brefeldin A（BFA）是一种真菌大环内酯，能够有效、可逆地抑制内质网和高尔基体之间的蛋白质运输和囊泡形成。
  12. GC11304 Azithromycin Dihydrate

    阿奇霉素二水合物; CP-62993 dihydrate

     A macrolide antibiotic
  13. GC14314 Aloperine

    苦豆碱

     An alkaloid with diverse biological activities
  14. GC13854 AG-490 (Tyrphostin B42)

    酪氨酸磷酸化抑制剂AG490

     AG-490 (Tyrphostin B42)是EGFR抑制剂,IC50为0.1 µM, AG-490对JAK2也有抑制作用。
  15. GC13843 Pyrazinamide

    吡嗪酰胺; Pyrazinecarboxamide; Pyrazinoic acid amide

     An antimycobacterial compound
  16. GC17340 Carbamazepine

    卡马西平; CBZ; NSC 169864

     卡马西平是一种钠通道阻滞剂，是一种抗惊厥药。
  17. GC15668 Meprednisone

    泼尼松

     A corticosteroid
  18. GC15493 Enalaprilat Dihydrate

    2,4-二氯苯基-2-(-1H-咪唑)乙醇

     The active metabolite of an ACE inhibitor
  19. GC14106 Adenosine

    腺苷; Adenine riboside; D-Adenosine

     A purine nucleoside
  20. GC12645 Imiquimod maleate

    马来酸咪喹莫特; R 837 maleate

    A TLR7 agonist
  21. GC10712 Imiquimod hydrochloride

    盐酸咪喹莫特; R 837 hydrochloride

    A TLR7 agonist
  22. GC12013 Sodium salicylate

    水杨酸钠; Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt

     水杨酸钠（水杨酸钠盐）抑制环加氧酶 2（COX-2）活性，与转录因子（NF-κB）激活无关。
  23. GC16508 Salicylic acid

    水杨酸; 2-Hydroxybenzoic acid

     An Analytical Reference Standard
  24. GC13870 Pravastatin

    普伐他汀; CS-514

     A potent HMG-CoA reductase inhibitor
  25. GC12920 Pregnenolone

    孕烯醇酮; 3β-Hydroxy-5-pregnen-20-one

     A natural steroid hormone
  26. GC11332 Pitavastatin

    匹伐他汀; NK-104

     Pitavastatin (NK-104) 是一种有效的羟甲基戊二酰辅酶A (HMG-CoA) 还原酶抑制剂。
  27. GC13206 Nicotinic Acid

    烟酸; Nicotinic acid; Vitamin B3

     烟酸（维生素 B3）是一种具有口服活性的水溶性维生素 B3，是人体必需的营养素。
  28. GC16441 Tigecycline mesylate

    甲磺酸替加环素; GAR-936 mesylate

     A glycylcycline antibiotic
  29. GC16410 Tigecycline hydrochloride

    盐酸替加环素; GAR-936 hydrochloride

     A glycylcycline antibiotic
  30. GC12830 Stavudine (d4T)

    司他夫定; d4T

     An inhibitor of HIV reverse transcriptase
  31. GC17113 Acitretin sodium

    阿维A钠; Ro 10-1670 sodium

     A retinoid
  32. GC14379 Adapalene sodium salt

    阿达帕林钠; CD 271 sodium salt

     An RARβ and RARγ agonist
  33. GC15578 Dienogest

    地诺孕素; STS 557

     A synthetic progestin and PR agonist
  34. GC16716 Sulindac

    舒林酸; MK-231

     A non-selective COX inhibitor
  35. GC14769 Carvedilol

    卡维地洛; BM 14190

     A β-adrenergic receptor antagonist
  36. GC13401 SJB3-019A SJB3-019A 是一种有效的新型 USP1 抑制剂，在促进 K562 细胞中 ID1 降解和细胞毒性方面的作用是 SJB2-043 的 5 倍，IC50 为 0.0781 μM。
  37. GC17985 Chenodeoxycholic Acid

    鹅去氧胆酸

     A primary bile acid
  38. GC12234 Dronedarone HCl

    盐酸决奈达隆

     An antiarrhythmic agent
  39. GC10760 XL335

    3-(3,4-二氟苯甲酰基)-1,2,3,6-四氢-1,1-二甲基氮杂卓[4,5-B]吲哚-5-甲酸1-甲基乙基酯,FXR-450; XL335; WAY-362450

     A potent and selective FXR agonist
  40. GC13071 Ridaforolimus (Deforolimus, MK-8669)

    42-(二甲基亚膦酰)雷帕霉素,MK-8669; Deforolimus; AP23573

     A rapamycin analog that selectively inhibits mTOR in mTORC1
  41. GC10975 GW4064

    3-(2,6-二氯苯基)-4-(3'-羧基-2-氯二苯乙烯-4-基)氧甲基-5-异丙基异恶唑

     GW4064作为合成的FXR激动剂，用于治疗胆汁淤积性肝病、代谢综合征和酒精性肝病。
  42. GC17804 GlyH-101

    GlyH101, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor II

     A reversible CFTR channel blocker
  43. GC17635 ML-323 A selective USP1-UAF1 deubiquitinase complex inhibitor
  44. GC13437 ZLN005 A small molecule activator of PGC-1α expression
  45. GC11056 Itraconazole

    伊曲康唑 ; R51211

     An antifungal agent and hedgehog pathway inhibitor
  46. GC14507 Azithromycin

    阿奇霉素; CP 62993

     A macrolide antibiotic
  47. GC16359 Rosuvastatin

    瑞舒伐他汀; ZD 4522

     An HMG-CoA reductase inhibitor
  48. GC17443 Metformin HCl

    盐酸二甲双胍; 1,1-Dimethylbiguanide hydrochloride

    A biguanide with diverse biological activities
  49. GC11895 Mevastatin

    美伐他汀; Compactin; ML236B

     An HMG-CoA reductase inhibitor
  50. GC13667 Temozolomide

    替莫唑胺; NSC 362856; CCRG 81045; TMZ

     替莫唑胺是一种口服活性烷化剂，可诱导 DNA 中 O6-甲基鸟嘌呤的形成，其在随后的 DNA 复制周期中与胸腺嘧啶错配，从而激活细胞凋亡途径，替莫唑胺可穿过血脑屏障并适用于恶性神经胶质瘤和转移性黑色素瘤。
  51. GC12993 Vancomycin hydrochloride

    盐酸万古霉素

    A glycopeptide antibiotic

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