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Home >> Signaling Pathways >> Ubiquitination/ Proteasome >> Autophagy

Autophagy(自噬)

Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.

Products for  Autophagy

  1. Cat.No. 产品名称 Information
  2. GC12017 Isoniazid

    异烟肼; INH; Isonicotinic acid hydrazide; Isonicotinic hydrazide

     An inhibitor of mycolic acid synthesis
  3. GC12226 Cisatracurium Besylate

    顺苯磺酸阿曲库铵; 51W89

     A competitive antagonist of nAChRs and non-depolarizing muscle relaxant
  4. GC15857 Sodium butyrate

    丁酸钠

     A short-chain fatty acid and HDAC inhibitor
  5. GC17082 Pirarubicin

    吡柔比星; THP

     An anthracycline antitumor antibiotic
  6. GC16486 Novobiocin Sodium

    新生霉素钠,Albamycin sodium; Cathomycin sodium

     An inhibitor of DNA gyrase
  7. GC14563 Ketanserin

    酮色林; R41468

     A potent 5-HT2 receptor antagonist
  8. GC17974 Latrepirdine dihydrochloride

    2,3,4,5-四氢-2,8-二甲基-5-[2-(6-甲基-3-吡啶基)乙基]-1H-吡啶并[4,3-B]吲哚二盐酸盐,Dimebolin dihydrochloride

     A neuroprotective agent
  9. GC12376 Maprotiline HCl

    盐酸马普替林

     A tricyclic antidepressant
  10. GC17229 Paroxetine HCl

    盐酸帕罗西汀; BRL29060 hydrochloride; BRL29060A

     A selective serotonin reuptake inhibitor
  11. GC16999 Nitrendipine

    尼群地平; BAY-E-5009

     An L-type calcium channel blocker
  12. GC14216 Chlorpromazine HCl

    盐酸氯丙嗪

     Chlorpromazine HCl是一种口服有效的、可透过血脑屏障的吩噻嗪类抗精神病药，能够有效抑制D2多巴胺受体和5-HT2A，具有很强的镇静作用。
  13. GC15024 Nifedipine

    硝苯地平; BAY-a-1040

     An L-type calcium channel blocker
  14. GC16921 Bromhexine HCl

    盐酸溴己新

     Bromhexine HCl 是一种有效且特异性的 TMPRSS2 蛋白酶抑制剂，IC50 为 0.75 μM。
  15. GC13974 Salbutamol Sulfate

    沙丁胺醇半硫酸盐; Albuterol hemisulfate; AH-3365 hemisulfate

     A β2-AR agonist
  16. GC10750 Dexmedetomidine HCl

    盐酸右美托咪定; (+)-Medetomidine hydrochloride; (S)-Medetomidine hydrochloride

     An α2-adrenoceptor agonist
  17. GC10132 Ciclopirox

    环吡酮胺; HOE296b

     An iron chelator, antifungal, and anticancer agent
  18. GC11885 Sevelamer HCl

    盐酸司维拉姆

     Sevelamer HCl 是一种磷酸盐结合药物，用于治疗慢性肾病患者的高磷血症；由与环氧氯丙烷交联的聚烯丙胺组成。
  19. GC14273 TTNPB (Arotinoid Acid)

    Ro 13-7410; Arotinoid acid; AGN191183

     A potent, selective RAR agonist
  20. GC13031 Trifluoperazine 2HCl

    盐酸三氟拉嗪；甲哌氟丙嗪；三氟吡拉嗪

     An anti-adrenergic and anti-dopaminergic agent
  21. GC10424 Tolbutamide

    甲苯磺丁脲

     A SUR1/Kir6.2 channel inhibitor
  22. GC12736 Thiamet G Thiamet G 是一种有效的 O-GlcNAcase 抑制剂 (Ki =21 nM)，用于提高 O-GlcNAcylation 水平。
  23. GC17151 Tempol

    阻聚剂701,4-Hydroxy-TEMPO

     A nitroxide and spin label with SOD mimetic activity
  24. GC15184 Taurine

    牛磺酸; 2-Aminoethanesulfonic acid

     A sulfur-containing amino acid
  25. GC13918 STF-62247

    N-(3-甲基苯基)-4-(4-吡啶)-2-噻唑胺

     Inducer of autophagy in renal cell carcinoma cells
  26. GC12516 Spironolactone

    螺内酯; SC9420

     An Analytical Reference Standard
  27. GC11033 Rupatadine Fumarate

    富马酸卢帕他定; UR-12592 Fumarate

     A histamine H1 and PAF receptor antagonist
  28. GC14263 Proflavine Hemisulfate

    硫酸原黄素,Proflavin hemisulfate; 3,6-Diaminoacridine hemisulfate

     Proflavine hemisulfate，一种吖啶染料，是一种已知的 DNA 嵌入剂。
  29. GC10458 Penfluridol

    五氟利多; R-16341

     A typical antipsychotic
  30. GC10678 Nicardipine HCl

    盐酸尼卡地平; YC-93

     An L-type calcium channel blocker
  31. GC13252 Meclizine 2HCl

    盐酸美克洛嗪; Meclozine dihydrochloride

     A histamine H1 receptor antagonist
  32. GC15929 Levosimendan

    左西孟旦; Simsndan; OR-1259

     A calcium sensitizer
  33. GC14764 Lamotrigine

    拉莫三嗪; LTG; BW430C

     An anticonvulsant
  34. GC15826 Isosorbide

    异山梨酯; D-Isosorbide; Dianhydro-D-glucitol

     A dianhydrohexitol
  35. GC10074 H 89 2HCl

    H-89二盐酸盐

     H-89 2HCl 是一种有效的选择性 camp 依赖性蛋白激酶 A 抑制剂，IC50 值为 48 nM，对 PKG、PKC、酪蛋白激酶和其他激酶表现出较弱的抑制作用 。
  36. GC17173 Felodipine

    非洛地平

     An L-type calcium channel inhibitor
  37. GC14968 Esmolol HCl

    盐酸艾司洛尔

     A β1-AR antagonist
  38. GC10326 Erythromycin Ethylsuccinate

    琥乙红霉素; Erythromycin ethyl succinate; EES

     Erythromycin Ethylsuccinate 是一种可用于治疗多种细菌感染的抗生素，其抗菌谱与青霉素相似或略宽。
  39. GC12846 Elaiophylin

    洋橄榄叶素,Azalomycin B; Gopalamicin; Efomycin E

     A macrodiolide antibiotic
  40. GC13502 Cysteamine HCl

    半胱胺盐酸盐; 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride

     A radioprotective aminothiol
  41. GC16332 Colistin Sulfate

    硫酸粘杆菌素; Polymyxin E sulfate

     An antibiotic
  42. GC15810 Clinofibrate

    克利贝特,S-8527

     A hypolipidemic agent
  43. GC14892 Clemastine Fumarate

    富马酸氯马斯汀; HS-592 fumarate; Meclastine fumarate

     A histamine H1 receptor antagonist
  44. GC14421 CFTRinh-172

    CFTR(inh)172, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor 172

     A potent CFTR channel blocker
  45. GC17341 Carprofen

    卡洛芬

     An NSAID used in animals
  46. GC12733 C646 C646是一种有效的选择性p300/CBP组蛋白乙酰转移酶抑制剂(Ki 400 nM),已被证明具有多效性,包括神经保护、抗癌和抗上皮间质转化(anti-EMT)作用。
  47. GC17683 Brefeldin A

    布雷非德菌素 A; BFA; Cyanein; Decumbin

     Brefeldin A（BFA）是一种真菌大环内酯，能够有效、可逆地抑制内质网和高尔基体之间的蛋白质运输和囊泡形成。
  48. GC11304 Azithromycin Dihydrate

    阿奇霉素二水合物; CP-62993 dihydrate

     A macrolide antibiotic
  49. GC14314 Aloperine

    苦豆碱

     An alkaloid with diverse biological activities
  50. GC13854 AG-490 (Tyrphostin B42)

    酪氨酸磷酸化抑制剂AG490

     AG-490 (Tyrphostin B42)是EGFR抑制剂,IC50为0.1 µM, AG-490对JAK2也有抑制作用。
  51. GC13843 Pyrazinamide

    吡嗪酰胺; Pyrazinecarboxamide; Pyrazinoic acid amide

     An antimycobacterial compound

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