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Home >> Signaling Pathways >> Microbiology & Virology

Microbiology & Virology(微生物学 & 病毒学)

Virology

A virus is a small infectious agent that replicates inside living cells. Viruses cause many human diseases from small illnesses, like influenza, to more deadly diseases, like hepatitis B and HIV. Our body’s immune system defends against viral infection by generating specific antibodies to bind to and neutralize viral particles and by cell mediated immunity that destroys infected host cells. read more

Products for  Microbiology & Virology

  1. Cat.No. 产品名称 Information
  2. GC26052 WAY-297407 WAY-297407 is a bioactive compound.
  3. GC25972 Sulfamethoxazole sodium Sulfamethoxazole sodium is an antibiotic used for bacterial infections.
  4. GC25867 Rilpivirine Hydrochloride

    TMC278

     Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
  5. GC25863 Riamilovir

    Triazavirin

     Riamilovir (Triazavirin) is a broad-spectrum antiviral drug candidate, which can be used for potential application against the Coronavirus 2019-nCoV.
  6. GC25784 Proflavine

    3,6-Diaminoacridine

     Proflavine (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria. It is a topical antiseptic used mainly in wound dressings.
  7. GC25782 Procaine penicillin G

    PGP, Penicillin G Procaine, Bicillin C-R

     Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic.
  8. GC25778 Potassium 1-Naphthaleneacetate

    KANU, Potassium alpha-naphthylacetate, α-Naphthaleneacetic Acid Potassium Salt, 1-NAA Potassium Salt

     Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
  9. GC25754 Piperaquine phosphate Piperaquine phosphate is an orally active bisquinolone antimalarial drug.
  10. GC25693 OX02983 OX02983 is a novel anthelmintic agent, actives against both egg and adult stages of Trichuris parasites, immobilising whipworm and reducing the ability of embryonated Trichuris muris eggs to establish infection in the mouse host.
  11. GC25688 Ormetoprim Ormetoprim (OMP) is an antibiotic to prevent the spread of disease in freshwater aquaculture.
  12. GC25679 Olanexidine Hydrochloride semihydrate

    OPB-2045, OPB-2045G

     Olanexidine (OPB-2045, OPB-2045G) is a monobiguanide compound with bactericidal activity.
  13. GC25671 NK01-63

    Coronastat

     NK01-63 (Coronastat) is a potent inhibitor of the SARS-CoV-2 3CL protease, which is a critical drug target for small molecule COVID-19, given its likely druggability and essentiality in the viral maturation and replication cycle.
  14. GC25655 Mupirocin calcium

    Pseudomonic acid A

     Mupirocin Calcium (Pseudomonic acid A) is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic.
  15. GC25579 LL-37(human) LL-37, human is a 37-residue, amphipathic, cathelicidin-derived peptide, which exhibits a broad spectrum of antimicrobial activity.
  16. GC25429 Fosfomycin calcium

    phosphomycin calcium, phosphonomycin calcium

     Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
  17. GC25425 Fluoroquinolonic Acid

    Ciprofloxacin Impurity A, Q-Acid

     Fluoroquinolonic Acid (Ciprofloxacin Impurity A, Q-Acid) is an antibiotic and antimicrobial agent.
  18. GC25401 Euquinine Euquinine is generally used as a febrifuge, antimalarial, and tonic.
  19. GC25362 Doxycycline monohydrate Doxycycline is a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity.
  20. GC25341 Desciclovir

    DCV, 6-Deoxyacyclovir, BW A515U

     Desciclovir (DCV, 6-Deoxyacyclovir, BW A515U) is a prodrug of the antiherpetic agent acyclovir (ACV) that converted into ACV by xanthine oxidase in humans.
  21. GC25306 CQ31 CQ31, a small molecule, selectively activates caspase activation and recruitment domain-containing 8 (CARD8).
  22. GC25249 CID-1517823

    ML328

     CID-1517823 (ML328) is a potent and selective inhibitor of bacterial AddAB and RecBCD helicase-nucleases, with IC50s of 1.0 and 4.8 μM.
  23. GC25218 Cephradine monohydrate Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
  24. GC25210 Ceftezole

    Celoslin, Falomesin

     Ceftezole (Celoslin, Falomesin) is a semi-synthetic first-generation cephalosporin with antibacterial activity.
  25. GC25209 Cefteram pivoxil Cefteram Pivoxil is the pivalate ester prodrug of cefteram, a semi-synthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity.
  26. GC25208 Cefatrizine Cefatrizine, a broad-spectrum, semisynthetic, first-generation cephalosporin with antibacterial activity, binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
  27. GC25182 Butoconazole Butoconazole is an imidazole antifungal used in gynecology.
  28. GC25181 Butenafine Butenafine is a synthetic benzylamine antifungal agent.
  29. GC25135 Besifloxacin Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis.
  30. GC25027 Absinthin

    Absynthine

     Absinthin (Absynthine) is a naturally produced triterpene lactone from Artemisia absinthium with anti-inflammatory properties. Absinthin significantly enhances the expression of matrix metalloproteinase-8 (MMP-8) and is a possible treatment candidate for Acute lung injury (ALI).
  31. GC68473 Methyl carnosate Methyl camosate 是一种从鼠尾草或迷迭香中分离出的二萜，具有强大的抗氧化和抗菌活性。
  32. GC68471 Nifurpirinol

    P-7138

     Nifurpirinol (P-7138) 是一种硝基芳香抗生素 (Antibiotic)，是细菌硝基还原酶 (NTR) 的底物。与甲硝唑相比，Nifurpirinol 是一种更有效的 prodrug，可在表达硝基还原酶的转基因模型中诱导细胞消融。
  33. GC68465 SDH-IN-1 SDH-IN-1 (compound 4i) 是一种琥珀酸脱氢酶 (SDH) 抑制剂，IC50 为 4.53 μM。SDH-IN-1 具有有效的抗真菌活性。SDH-IN-1 对 S. sclerotiorum 显示出有效的活性 (EC50 为 0.14 mg/L)。
  34. GC68457 Mab Aspartate Decarboxylase-IN-1 Mab Aspartate Decarboxylase-IN-1 是一种有效的天冬氨酸脱羧酶 aspartate decarboxylase (PanD) 抑制剂，IC50 值为 56.3 µM。 Mab Aspartate Decarboxylase-IN-1 具有抗菌活性。
  35. GC68449 CA inhibitor 1

    GS-6207 analog

     CA inhibitor 1 (GS-6207 analog) 是一种有效的 HIV 衣壳抑制剂，可用于抑制 HIV。
  36. GC68428 Rimantadine-d4 hydrochloride Rimantadine-d4 hydrochloride (1-Rimantadine-d4) 是 Rimantadine 的氘代物。Rimantadine (Flumadine)是抗流感病毒化合物。
  37. GC68408 (R)-Praziquantel-d11

    (R)-吡喹酮 D11

     (R)-Praziquantel D11 是 (R)-Praziquantel 的氘代物。(R)-Praziquantel 是 Praziquantel 的活性对映体，是一种人 5-HT2B 受体的部分激动剂。(R)-Praziquantel 用作驱虫药，抗血吸虫。
  38. GC68403 Dusquetide

    SGX942

     Dusquetide (SGX942) 是第一类天然防御调节因子 (IDR)。Dusquetide 通过与 p62 结合调节 PAMPs 和 DAMPs 的天然免疫应答。Dusquetide 在减轻炎症和增加细菌感染清除方面都显示出活性。
  39. GC68402 Danofloxacin-d3

    达氟沙星d3

     Danofloxacin-d3 是 Danofloxacin 的氘代物。Danofloxacin 是一种具有口服活性第三代氟喹诺酮抗菌剂，对大多数革兰氏阴性和革兰氏阳性细菌，支原体和衣原体物种具有广谱的活性，并通过抑制细菌的 DNA 回转酶 (bacterial DNA-gyrase) 发挥抗菌作用。
  40. GC68401 Lehmannine Lehmannine 是一种喹诺烷类生物碱 (bioalkaloid)，具有抗菌、抗炎和抗肿瘤活性。
  41. GC68359 Pefloxacin-d5

    Pefloxacinium-d5

     Pefloxacin-d5 是 4-Nitrobenzonitrile 氘代物。
  42. GC68315 Salannin Salannin，一种柠檬苦素，具有抗溃疡和杀精活性。Salannin 对革兰氏阳性菌和革兰氏阴性菌均有抗菌活性。
  43. GC68300 Palivizumab

    MEDI 493

     Palivizumab (MEDI 493) 是一种人源化呼吸道合胞病毒单克隆抗体，可减少呼吸道合胞病毒感染 (RSV)。
  44. GC68297 Bepirovirsen Bepirovirsen 是一种反义寡核苷酸，靶向所有 HBV 信使 RNAs。Bepirovirsen 导致 HBV 来源的 RNAs、HBV DNA 和病毒蛋白的减少。Bepirovirsen 可用于慢性 HBV 感染的研究。Bepirovirsen 结合位点序列 (GCACTTCGCTTCACCTCTGC)。
  45. GC68286 Motavizumab

    MEDI-524

     Motavizumab (MEDI-524) 是一种 anti-human RSV (呼吸道合胞病毒) 单克隆抗体。Motavizumab 可用于高危婴儿的呼吸道合胞病毒感染的研究。
  46. GC68233 3-Aminobutanoic acid 3-Aminobutanoic acid 是一种 β-氨基酸。3-Aminobutanoic acid 可以保护植物免受致病疫霉的攻击感染。3-Aminobutanoic acid 对病原体具有不同程度的易感性。
  47. GC68217 HCV-IN-30 HCV-IN-30 (compound 48) 是一种丙型肝炎病毒 HCV NS5A 复制复合物抑制剂，抑制 HCV 1a 和 1b 型复制的 IC50 分别为 901 和 102 nM。
  48. GC68208 Salazopyridazine Salazopyridazine 是一种抗菌剂。Salazopyridazine 对溃疡性结肠炎有抑制作用。Salazopyridazine 可用于风湿病的研究。
  49. GC68144 Ticlatone

    6-Chlorobenzo[d]isothiazol-3(2H)-one

     Ticlatone 是一种抗真菌剂，可用于真菌病的研究。
  50. GC68050 Pritelivir mesylate hydrate

    AIC316 mesylate hydrate; BAY 57-1293 mesylate hydrate

     Pritelivir mesylate hydrate (BAY 57-1293 mesylate hydrate) 是一种病毒解旋酶-引物酶复合物 (helicase-primase complex) 抑制剂，在体外和单纯疱疹病毒 (HSV) 感染的动物模型中均具有抗病毒活性。Pritelivir mesylate hydrate 对 1 型和 2 型单纯疱疹病毒 (HSV-1 和 HSV-2) 具有活性，对 HSV1-2 的 IC50 为 0.02 μM。
  51. GC68026 SSAA09E3 SSAA09E3 是一种 SARS-CoV 进入抑制剂，抑制 SARS/HIV 假型病毒进入 293T 细胞，EC50 为 9.7 μM。也抑制 Vero 细胞中的 SARS-CoV 感染，EC50 为 0.15 μM。

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