Antibiotic(抗生素)

Cat.No. 产品名称 Information

GC66053 Clavulanic acid Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias.

GC65875 Grepafloxacin hydrochloride

OPC-17116 hydrochloride; dl-Grepafloxacin hydrochloride

Grepafloxacin (OPC-17116) hydrochloride 是一种口服活性氟喹诺酮类抗生素 (antibiotic)，对包括肺炎链球菌在内的社区获得性呼吸道病原体具有有效活性。Grepafloxacin hydrochloride 具有较高的组织渗透性和良好的药效学特性。

GC65563 Spiramycin I

螺旋霉素 I

Spiramycin I (Foromacidin A) is a main component of spiramycin, which is a macrolide antimicrobial agent with broad spectrum antibiotic activity.

GC65557 Cladosporin

枝孢菌素

Cladosporin 是一种真菌代谢物，在 Cladosporium cladosporioid 的菌丝体中产生。含浓度 75 μg/mL Cladosporin 的琼脂培养基可完全抑制多种皮肤癣菌的生长。

GC65195 2-O-Acetyl-20-hydroxyecdysone

2-乙酰基Β-蜕皮甾酮,20-Hydroxyeedysone 2-acetate

An ecdysone steroid hormone

GC65088 Atovaquone-d5

Atavaquone-d5

Atovaquone-d5 (Atavaquone-d5) 是 Atovaquone 的氘代物。Atovaquone (Atavaquone) 是一种有效的、具有口服活性的选择性寄生虫线粒体细胞色素 bc1 (parasite's mitochondrial cytochrome bc1) 复合物的抑制剂。Atovaquone 抑制人类和 P. falciparum 细胞色素 bc1 活性，IC50 值分别为 460 nM 和 2.0 nM。Atovaquone 是一种抗疟 (antimalarial agent) 试剂，有潜力用于肺孢子虫肺炎、弓形体病、疟疾和巴贝斯虫病的相关研究。

GC65017 Bedaquiline impurity 2-d6 Bedaquiline impurity 2-d6 是 Bedaquiline 氘代物。Bedaquiline (TMC207) 是一种二芳基喹啉药物，通过同时靶向 c-亚基和 ε-亚基来抑制结核分枝杆菌 (Mtb) F1FO-ATP合酶。Bedaquiline 具有解偶联活性。Bedaquiline 有用于耐多药结核病的潜力。

GC64757 Framycetin sulfate

新霉素B硫酸盐,Neomycin B sulfate; Fradiomycin B sulfate

Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM, and competes for specific divalent metal ion binding sites in RNase P RNA, also inhibits hammerhead ribozyme with a Ki of 13.5 μM.

GC64753 Enduracidin

恩拉霉素; Enramycin

Enduracidin (Enramycin) 是由链霉菌产生的一种多肽抗生素。

GC64709 MptpB-IN-1 MptpB-IN-1 (Compound 13) 是一种有效的、具有口服活性的 MptpB 抑制剂。结核分枝杆菌蛋白-酪氨酸-磷酸酶 B (MptpB) 是一种分泌的毒力因子，可破坏宿主的抗菌活性。MptpB-IN-1 可降低耐多药结核分枝杆菌的存活率和感染负担。

GC19941 DL-Leucic Acid

GC64291 Moxifloxacin-d4

莫西沙星 d4

An internal standard for the quantification of moxifloxacin

GC64254 Rifampicin-d4

Rifampin-d4; Rifamycin AMP-d4

Rifampicin-d4 (Rifampin-d4) 是 Rifampicin 的氘代物。Rifampicin是一种有效的广谱抗生素，可抵抗细菌病原体。Rifampicin 具有抗流感病毒活性。

GC64237 Tellimagrandin II

Eugeniin

Tellimagrandin II (Eugeniin)，是 4C1-葡萄糖衍生的鞣花丹宁系列的第一个中间体，也抑制Staphylococcus aureus的耐药性。

GC64190 Sultamicillin

舒他西林

Sultamicillin is a newly developed antibiotic in which ampicillin and the β-lactamase inhibitor sulbactam are linked as an ester.

GC64179 (R)-Fangchinoline

汉防己乙素,Thalrugosine; Thaligine

Fangchinoline, a bisbenzylisoquinoline alkaloid, is a novel HIV-1 inhibitor with pain-relieving, blood pressure-depressing, and antibiotic activities.