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HIV(人类免疫缺陷病毒)

HIV (human immunodeficiency virus) is a lentivirus that infect immune system. It cause immune system failure and lead to AIDS (acquired immnudeficiency syndrome).

Products for  HIV

  1. Cat.No. 产品名称 Information
  2. GC39238 BRD-K98645985 BRD-K98645985 是一类 12 元大环内酰胺,也是一种 BAF (Brg/Brahma-associated factors) 转录阻遏的抑制剂,EC50 为 ~2.37 µM。BRD-K98645985 结合 ARID1A 特异的 BAF 复合物,防止核小体定位,并有效逆转 HIV-1 潜伏期,并且无 T 细胞毒性。
  3. GC46075 5,6-dimethyl-2-Thiouracil

    5,6-二甲基--2-硫脲嘧啶

    A heterocyclic building block
  4. GC39111 Tripterifordin

    雷公藤福定

    Tripterifordin 从 Tripterygium wilfordii 的根中分离出来,在 H9 淋巴细胞中具有显着的抗 HIV 复制活性,EC50 值为 3100 nM。
  5. GC39088 Triptonine B

    18-O-(3-糠酰)雷公藤春碱

    Triptonine B 是一种从 Tripterygium hypoglaucum 和 Tripterygium wilfordii 中分离的倍半萜吡啶生物碱,在 H9 淋巴细胞中,可抑制 HIV 复制,EC50 值 <0.10 μg/mL。
  6. GC46020 Stachybotrysin B A fungal metabolite with antiviral and anticancer activities
  7. GC45998 Mitoxantrone-d8

    米托蒽醌-D8,Mitozantrone-d8; NSC 301739-d8

    An internal standard for the quantification of mitoxantrone
  8. GC38854 TAT TFA TAT TFA (YGRKKRRQRRR) 源自人免疫缺陷病毒 (HIV-1) 的转录反式激活因子 (TAT),是一种穿透细胞的肽。TAT 可以增加异源蛋白质的产量和溶解度。
  9. GC38790 GS-6207

    HIV-1衣壳抑制剂GS-6207,GS-6207

    GS-6207 (GS-6207) 是一种 HIV-1 衣壳抑制剂。
  10. GC38742 BRD-6929

    JQ12

    An HDAC1 and HDAC2 inhibitor
  11. GC45926 Nelfinavir-d3 An internal standard for the quantification of nelfinavir
  12. GC45825 Etravirine-d6

    R165335-d6, TMC125-d6

    An internal standard for the quantification of etravirine
  13. GC45788 Maraviroc-d6

    马拉韦罗D6

    An internal standard for the quantification of maraviroc
  14. GC45766 Amprenavir-d4

    安瑞那韦 d4

    A neuropeptide with diverse biological activities
  15. GC45650 Des(benzylpyridyl) Atazanavir

    Atazanavir metabolite M1

    A metabolite of atazanavir
  16. GC38662 Dimercaprol

    二巯基丙醇; 2,3-Dimercapto-1-propanol; Dithioglycerol

    Dimercaprol (Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol) is an acrolein scavenger that inhibits HIV-1 tat activity, viral production, and infectivity in vitro.
  17. GC38437 Fangchinoline

    防己诺林碱

    An alkaloid with diverse biological activities
  18. GC38109 Enfuvirtide acetate

    醋酸恩夫韦地; T20 acetate; DP178 acetate

    A peptide inhibitor of HIV-1 fusion
  19. GA20545 Acetyl-Pepstatin

    醋酸胃酶抑素,Pepstatin A acetate

    Acetyl-pepstatin 是一种有效的经典天冬氨酸蛋白酶 (PRs) 抑制剂,XMRV PR 和 HIV-1 PR Ki 值分别为 712 nM 和 13 nM。
  20. GC45604 β-Rubromycin

    BETA-玉红霉素

    A bacterial metabolite
  21. GC45337 3-Hydroxyterphenyllin

    NSC 299113

    A fungal metabolite with diverse biological activities
  22. GC37968 Zingibroside R1

    姜状三七皂苷R1

    A triterpene saponin and an active metabolite of ginsenoside Ro
  23. GC37760 Tenofovir Disoproxil

    替诺福韦酯; Bis(POC)-PMPA; GS 4331

    A prodrug of the antiviral tenofovir
  24. GC37759 Tenofovir alafenamide hemifumarate

    替诺福韦艾拉酚胺富马酸盐,GS-7340 hemifumarate

    Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.
  25. GC37758 Tenofovir alafenamide fumarate

    替诺福韦阿拉芬酰胺富马酸酯,GS-7340 (fumarate)

    Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.
  26. GC37724 TAK-779

    Takeda 779

    An antagonist of CCR5, CXCR3, and CCR2b
  27. GC37690 Stavudine sodium

    司他夫定钠; d4T sodium

    An inhibitor of HIV reverse transcriptase
  28. GC36798 Oleanonic acid

    齐墩果酮酸,3-Oxooleanolic acid

    Oleanonic Acid (3-Ketooleanolic Acid, 3-Oxooleanolic acid), extracted from Pistacia terebinthus galls, is a cell cycle inhibitor and used as antitumor agents.
  29. GC36702 NBD-557

    N-(4-溴苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺

    NBD-557是HIV-1抑制剂。
  30. GC36550 Mavorixafor trihydrochloride

    AMD-070 trihydrochloride

    A CXCR4 antagonist
  31. GC36350 IT1t A CXCR4 antagonist
  32. GC36320 InteriotherinA

    内南五味子酯A

    Interiotherin A 是具有从 Kadsura 内部分离的含二苯并环辛二烯骨架的木脂素。 Interiotherin A 抑制 HIV 复制并且表现出抗 HIV 活性,它具有代谢产物和抗 HIV 的作用。
  33. GC36310 Indinavir sulfate

    硫酸茚地那韦; MK-639; L735524

    An HIV-1 protease inhibitor
  34. GC36309 Indinavir

    茚地那韦; MK-639 free base; L-735524 free base

    Indinavir sulfate (Crixivan, L-735524, MK-639) is a specific and potent inhibitor of HIV-1 protease and is widely used in the treatment of AIDS.
  35. GC36235 HIV-1 integrase inhibitor 4 HIV-1 integrase inhibitor 4 是一种 HIV-1 整合酶链转移 (INST) 抑制剂,其 IC50 值为 3.7 nM。
  36. GC36234 HIV-1 integrase inhibitor 3 HIV-1 integrase inhibitor 3 是一种 HIV-1 整合酶链转移 (INST) 抑制剂,其 IC50 值为 2.7 nM。
  37. GC36233 HIV-1 integrase inhibitor 2

    6-氯-2-甲基-4-苯基-ALPHA-丙基-3-喹啉乙酸,CX05168; CX04328

    HIV-1 整合酶抑制剂 2 (CX05168) 是一种基于喹啉的 LEDGF/p75 和 HIV 整合酶的蛋白-蛋白相互作用抑制剂。
  38. GC36232 HIV-1 inhibitor-3

    1-((2R,3R,4S,5S)-3,5-二氟-4-羟基-5-(羟甲基)四氢呋喃-2-基)嘧啶-2,4(1H,3H)-二酮

    HIV-1 inhibitor-3 是一种抗 HIV 病毒感染的抑制剂,详细信息请参考专利文献 US2018360927。
  39. GC36143 Glabranine

    光甘草宁;欧亚甘草宁;裸禾蕨黄素

    Glabranine 是从 Tephrosia s.p 中分离出一种类黄酮,在体外对登革病毒发挥抑制作用。Glabranine 与 DENV 2 型 (DENV2) E 蛋白的可溶性胞外域形成相互作用。
  40. GC36072 Fostemsavir Tris

    BMS-663068 Tris

    Fostemsavir Tris (BMS-663068 (Tris)) 是HIV-1附着抑制剂。
  41. GC36033 FC131 TFA An inhibitor of CXCR4 activation
  42. GC35835 Delavirdine

    地拉韦啶; U 90152; BHAP-U 90152

    A non-nucleoside reverse transcriptase inhibitor
  43. GC35823 DDX3-IN-1 DDX3-IN-1 (Compound 16f) 是 DEAD-box 多肽 3 (DDX3) 抑制剂。DDX3-IN-1 具有抗病毒活性,对 HIV 和 HCV 的 CC50 分别为 50 和 36 μM。
  44. GC35790 Cys-TAT(47-57)

    Cys-[HIV-Tat (47-57)]

    Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) 是能穿透细胞的富含精氨酸的十二肽,是 HIV-1 反式激活蛋白衍生物。
  45. GC35731 Corydine

    紫堇定

    An aporphine alkaloid with diverse biological activities
  46. GC35650 Cenicriviroc Mesylate

    TAK-652 Mesylate; TBR-652 Mesylate

    An antagonist of CCR5 and CCR2
  47. GC35510 BI 224436

    暂无

    BI 224436是一种新型的HIV-1非催化性位点整合酶抑制剂,对HIV-1实验室菌株的EC50值小于15 nM。
  48. GC35508 Bevirimat

    贝韦立马; PA-457; MPC-4326; YK FH312

    An inhibitor of HIV-1 virion maturation
  49. GC35487 Bellidifolin

    龙胆山酮酚

    Bellidifolin 是从獐牙菜的茎中提取的一种呫吨酮 (xanthone) 化合物,具有保肝、降血糖、抗氧化、抗炎、抗肿瘤作用。Bellidifolin 能作为病毒蛋白 R (Vpr) 的抑制剂。
  50. GC35208 9-Propenyladenine

    替诺福韦酯杂质; Mutagenic Impurity of Tenofovir Disoproxil; Tenofovir Impurity 2

    9-Propenyladenine 是富马酸替诺福韦二吡呋酯中的诱变杂质。 替诺福韦是一种抗逆转录病毒药物,是核苷酸类似物逆转录酶抑制剂,能阻断HIV-1和HBV的逆转录酶。
  51. GC35147 5-(N,N-Hexamethylene)-amiloride

    阿米洛利,Hexamethylene amiloride; HMA

    An amiloride derivative with diverse biological activities

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