HIV(人类免疫缺陷病毒)
HIV (human immunodeficiency virus) is a lentivirus that infect immune system. It cause immune system failure and lead to AIDS (acquired immnudeficiency syndrome).
Products for HIV
- Cat.No. 产品名称 Information
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GC39238
BRD-K98645985
BRD-K98645985 是一类 12 元大环内酰胺,也是一种 BAF (Brg/Brahma-associated factors) 转录阻遏的抑制剂,EC50 为 ~2.37 µM。BRD-K98645985 结合 ARID1A 特异的 BAF 复合物,防止核小体定位,并有效逆转 HIV-1 潜伏期,并且无 T 细胞毒性。
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GC46075
5,6-dimethyl-2-Thiouracil
5,6-二甲基--2-硫脲嘧啶
A heterocyclic building block -
GC39111
Tripterifordin
雷公藤福定
Tripterifordin 从 Tripterygium wilfordii 的根中分离出来,在 H9 淋巴细胞中具有显着的抗 HIV 复制活性,EC50 值为 3100 nM。 -
GC39088
Triptonine B
18-O-(3-糠酰)雷公藤春碱
Triptonine B 是一种从 Tripterygium hypoglaucum 和 Tripterygium wilfordii 中分离的倍半萜吡啶生物碱,在 H9 淋巴细胞中,可抑制 HIV 复制,EC50 值 <0.10 μg/mL。 -
GC46020
Stachybotrysin B
A fungal metabolite with antiviral and anticancer activities
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GC45998
Mitoxantrone-d8
米托蒽醌-D8,Mitozantrone-d8; NSC 301739-d8
An internal standard for the quantification of mitoxantrone -
GC38854
TAT TFA
TAT TFA (YGRKKRRQRRR) 源自人免疫缺陷病毒 (HIV-1) 的转录反式激活因子 (TAT),是一种穿透细胞的肽。TAT 可以增加异源蛋白质的产量和溶解度。
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GC38790
GS-6207
HIV-1衣壳抑制剂GS-6207,GS-6207
GS-6207 (GS-6207) 是一种 HIV-1 衣壳抑制剂。 -
GC38742
BRD-6929
JQ12
An HDAC1 and HDAC2 inhibitor -
GC45926
Nelfinavir-d3
An internal standard for the quantification of nelfinavir
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GC45825
Etravirine-d6
R165335-d6, TMC125-d6
An internal standard for the quantification of etravirine -
GC45788
Maraviroc-d6
马拉韦罗D6
An internal standard for the quantification of maraviroc -
GC45766
Amprenavir-d4
安瑞那韦 d4
A neuropeptide with diverse biological activities -
GC45650
Des(benzylpyridyl) Atazanavir
Atazanavir metabolite M1
A metabolite of atazanavir -
GC38662
Dimercaprol
二巯基丙醇; 2,3-Dimercapto-1-propanol; Dithioglycerol
Dimercaprol (Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol) is an acrolein scavenger that inhibits HIV-1 tat activity, viral production, and infectivity in vitro. -
GC38437
Fangchinoline
防己诺林碱
An alkaloid with diverse biological activities -
GC38109
Enfuvirtide acetate
醋酸恩夫韦地; T20 acetate; DP178 acetate
A peptide inhibitor of HIV-1 fusion -
GA20545
Acetyl-Pepstatin
醋酸胃酶抑素,Pepstatin A acetate
Acetyl-pepstatin 是一种有效的经典天冬氨酸蛋白酶 (PRs) 抑制剂,XMRV PR 和 HIV-1 PR Ki 值分别为 712 nM 和 13 nM。 -
GC45604
β-Rubromycin
BETA-玉红霉素
A bacterial metabolite -
GC45337
3-Hydroxyterphenyllin
NSC 299113
A fungal metabolite with diverse biological activities -
GC37968
Zingibroside R1
姜状三七皂苷R1
A triterpene saponin and an active metabolite of ginsenoside Ro -
GC37760
Tenofovir Disoproxil
替诺福韦酯; Bis(POC)-PMPA; GS 4331
A prodrug of the antiviral tenofovir -
GC37759
Tenofovir alafenamide hemifumarate
替诺福韦艾拉酚胺富马酸盐,GS-7340 hemifumarate
Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. -
GC37758
Tenofovir alafenamide fumarate
替诺福韦阿拉芬酰胺富马酸酯,GS-7340 (fumarate)
Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. -
GC37724
TAK-779
Takeda 779
An antagonist of CCR5, CXCR3, and CCR2b -
GC37690
Stavudine sodium
司他夫定钠; d4T sodium
An inhibitor of HIV reverse transcriptase -
GC36798
Oleanonic acid
齐墩果酮酸,3-Oxooleanolic acid
Oleanonic Acid (3-Ketooleanolic Acid, 3-Oxooleanolic acid), extracted from Pistacia terebinthus galls, is a cell cycle inhibitor and used as antitumor agents. -
GC36702
NBD-557
N-(4-溴苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺
NBD-557是HIV-1抑制剂。 -
GC36550
Mavorixafor trihydrochloride
AMD-070 trihydrochloride
A CXCR4 antagonist -
GC36350
IT1t
A CXCR4 antagonist
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GC36320
InteriotherinA
内南五味子酯A
Interiotherin A 是具有从 Kadsura 内部分离的含二苯并环辛二烯骨架的木脂素。 Interiotherin A 抑制 HIV 复制并且表现出抗 HIV 活性,它具有代谢产物和抗 HIV 的作用。 -
GC36310
Indinavir sulfate
硫酸茚地那韦; MK-639; L735524
An HIV-1 protease inhibitor -
GC36309
Indinavir
茚地那韦; MK-639 free base; L-735524 free base
Indinavir sulfate (Crixivan, L-735524, MK-639) is a specific and potent inhibitor of HIV-1 protease and is widely used in the treatment of AIDS. -
GC36235
HIV-1 integrase inhibitor 4
HIV-1 integrase inhibitor 4 是一种 HIV-1 整合酶链转移 (INST) 抑制剂,其 IC50 值为 3.7 nM。
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GC36234
HIV-1 integrase inhibitor 3
HIV-1 integrase inhibitor 3 是一种 HIV-1 整合酶链转移 (INST) 抑制剂,其 IC50 值为 2.7 nM。
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GC36233
HIV-1 integrase inhibitor 2
6-氯-2-甲基-4-苯基-ALPHA-丙基-3-喹啉乙酸,CX05168; CX04328
HIV-1 整合酶抑制剂 2 (CX05168) 是一种基于喹啉的 LEDGF/p75 和 HIV 整合酶的蛋白-蛋白相互作用抑制剂。 -
GC36232
HIV-1 inhibitor-3
1-((2R,3R,4S,5S)-3,5-二氟-4-羟基-5-(羟甲基)四氢呋喃-2-基)嘧啶-2,4(1H,3H)-二酮
HIV-1 inhibitor-3 是一种抗 HIV 病毒感染的抑制剂,详细信息请参考专利文献 US2018360927。 -
GC36143
Glabranine
光甘草宁;欧亚甘草宁;裸禾蕨黄素
Glabranine 是从 Tephrosia s.p 中分离出一种类黄酮,在体外对登革病毒发挥抑制作用。Glabranine 与 DENV 2 型 (DENV2) E 蛋白的可溶性胞外域形成相互作用。 -
GC36072
Fostemsavir Tris
BMS-663068 Tris
Fostemsavir Tris (BMS-663068 (Tris)) 是HIV-1附着抑制剂。 -
GC36033
FC131 TFA
An inhibitor of CXCR4 activation
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GC35835
Delavirdine
地拉韦啶; U 90152; BHAP-U 90152
A non-nucleoside reverse transcriptase inhibitor -
GC35823
DDX3-IN-1
DDX3-IN-1 (Compound 16f) 是 DEAD-box 多肽 3 (DDX3) 抑制剂。DDX3-IN-1 具有抗病毒活性,对 HIV 和 HCV 的 CC50 分别为 50 和 36 μM。
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GC35790
Cys-TAT(47-57)
Cys-[HIV-Tat (47-57)]
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) 是能穿透细胞的富含精氨酸的十二肽,是 HIV-1 反式激活蛋白衍生物。 -
GC35731
Corydine
紫堇定
An aporphine alkaloid with diverse biological activities -
GC35650
Cenicriviroc Mesylate
TAK-652 Mesylate; TBR-652 Mesylate
An antagonist of CCR5 and CCR2 -
GC35510
BI 224436
暂无
BI 224436是一种新型的HIV-1非催化性位点整合酶抑制剂,对HIV-1实验室菌株的EC50值小于15 nM。 -
GC35508
Bevirimat
贝韦立马; PA-457; MPC-4326; YK FH312
An inhibitor of HIV-1 virion maturation -
GC35487
Bellidifolin
龙胆山酮酚
Bellidifolin 是从獐牙菜的茎中提取的一种呫吨酮 (xanthone) 化合物,具有保肝、降血糖、抗氧化、抗炎、抗肿瘤作用。Bellidifolin 能作为病毒蛋白 R (Vpr) 的抑制剂。 -
GC35208
9-Propenyladenine
替诺福韦酯杂质; Mutagenic Impurity of Tenofovir Disoproxil; Tenofovir Impurity 2
9-Propenyladenine 是富马酸替诺福韦二吡呋酯中的诱变杂质。 替诺福韦是一种抗逆转录病毒药物,是核苷酸类似物逆转录酶抑制剂,能阻断HIV-1和HBV的逆转录酶。 -
GC35147
5-(N,N-Hexamethylene)-amiloride
阿米洛利,Hexamethylene amiloride; HMA
An amiloride derivative with diverse biological activities