HIV(人类免疫缺陷病毒)

Cat.No. 产品名称 Information

GC32306 Islatravir (MK-8591)

2'-脱氧-4'-C-乙炔基-2-氟腺苷,MK-8591

A nucleoside reverse transcriptase inhibitor

GC32210 Gomisin G

戈米辛 G

戈米辛G(GomisinG)是一抗HIV活性的天然化合物。

GC32192 Sodium copper chlorophyllin

叶绿素铜钠

叶绿素铜钠对流感病毒和 HIV 具有抗病毒活性，IC50 为 50 至 100 μM 两者。

GC32191 Celgosivir (MBI 3253)

MBI 3253; MDL 28574; MX3253

Celgosivir (MBI 3253) (MBI 3253; MDL 28574; MX3253) 是一种 α-葡萄糖苷酶 I 抑制剂；体外试验中抑制牛病毒性腹泻病毒 (BVDV)，IC50 为 1.27 μM。

GC32145 ABX464

ABX464

ABX464 (SPL-464) is a novel anti-HIV molecule that inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) from 5 different donors with IC50 ranging between 0.1 μM and 0.5 μM.

GC32142 Ditiocarb sodium (Sodium diethyldithiocarbamate)

二乙基二硫代氨基甲酸钠; Sodium diethyldithiocarbamate

Ditiocarb sodium (Sodium diethyldithiocarbamate) (Sodium diethyldithiocarbamate) 是铜胶结率的促进剂。

GC32135 TAK-220 A CCR5 antagonist

GC32124 Trovirdine (LY300046)

曲韦定; LY300046

Trovirdine (LY300046) 在使用异聚引物/模板（寡-DNA/核糖体 RNA）和 dGTP 作为底物时抑制 HIV-1 RT，IC50 为 7 nM。

GC32110 Vesnarinone (OPC-8212)

维司力农; OPC-8212

A PDE3 inhibitor and ERG1 channel blocker

GC32074 Celgosivir hydrochloride (MBI 3253 (hydrochloride))

MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride

Celgosivir hydrochloride (MBI 3253 (hydrochloride)) (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) 是一种 α-葡萄糖苷酶 I 抑制剂；体外试验中抑制牛病毒性腹泻病毒 (BVDV)，IC50 为 1.27 μM。

GC32060 Bictegravir (GS-9883)

比克替拉韦,GS-9883

An HIV-1 integrase inhibitor

GC31881 MS417 (GTPL7512)

GTPL7512

MS417 (GTPL7512) 是一种选择性 BET 特异性 BRD4 抑制剂，与 BRD4-BD1 和 BRD4-BD2 结合，IC50 分别为 30、46 nM 和 Kds 分别为 36.1、25.4 nM，对 CBP BRD 的选择性较弱 (IC50, 32.7 &#956 ;M)。

GC31715 Letrazuril

来曲珠利

Letrazuril是双胍类的对映体类似物，是一种苯乙腈可用于预防和治疗家禽中的球虫感染。

GC31685 Pentosan Polysulfate

4-O-甲基-ALPHA-D-葡糖酸基-BETA-D-木聚糖

Pentosan Polysulfate Sodium (PPS, Elmiron) is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also exhibits anti-HIV-1 activity.

GC31140 Oxindole (Indolin-2-one)

2-吲哚酮,Indolin-2-one

An aromatic heterocycle and starting material

GC30862 L-Cycloserine ((S)-4-Amino-3-isoxazolidone)

环丝氨酸,(S)-Cycloserine; (S)-4-Amino-3-isoxazolidone

An inhibitor of sphingolipid synthesis and aminotransferases

GC30119 9-Aminoacridine (Aminacrine)

9-氨基吖啶; Aminacrine

9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.