RSPO1 Mouse
目录号 : GP24449R-Spondin-1 Mouse Recombinant
Sample solution is provided at 25 µL, 10mM.
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RSPO1 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 254 amino acids (21-265a.a.) andhaving a molecular mass of 28.2kDa (Molecular size on SDS-PAGE will appear atapproximately 28-40kDa).RSPO1 is expressed with an 9 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.
| Purity | Greaterthan 90.0% as determined by SDS-PAGE. | Source | Sf9, Baculovirus cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | R-spondin-1; Cristin-3; mCristin-3; Roof plate-specificspondin-1; Rspo1; RSPO; R-spondin 1;R-spondin; Rspondin; CRISTIN3. | ||
| Amino Acid Sequence | ADPSRGIKGKRQRRISAEGS QACAKGCELC SEVNGCLKCS PKLFILLERN DIRQVGVCLP SCPPGYFDAR NPDMNKCIKCKIEHCEACFS HNFCTKCQEG LYLHKGRCYP ACPEGSTAAN STMECGSPAQ CEMSEWSPWG PCSKKRKLCGFRKGSEERTR RVLHAPGGDH TTCSDTKETR KCTVRRTPCP EGQKRRKGGQ GRRENANRHP ARKNSKEPGSNSRRHKGQQQ PQPGTTGPLT SVGPTWAQHH HHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | RSPO1 protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol. | ||
R-Spondin-1(Rspo1) is a part of the Rspondin family. Rspo1 plays a role as an activator ofthe canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors.Rspo1 induces the onset of crypt cell proliferation and increases intestinalepithelial healing effect. Rspo1 is negatively regulating the TGF-beta pathway.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.