Schaftoside
(Synonyms: 夏佛塔苷) 目录号 : GN10091
A flavonoid C-glycoside with diverse biological activities
Cas No.:51938-32-0
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >99.50%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
| Cell experiment [1]: | |
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Cell lines |
M. incognita, A. erubescens |
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Preparation method |
The solubility of this compound in DMSO is >16.3mg/mL. General tips for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months. |
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Reacting condition |
72 h |
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Applications |
Schaftoside possessed strong nematicidal activity against M. incognita with the LC50 of 114.66 μg/mL. Schaftoside showed strong nematicidal activity against the crude extract of A. erubescens and exhibited nematicidal activity against the root-knot nematode with a LC50 value of 258.11 μg/mL. |
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Other notes |
Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal. |
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References: [1]. Du, Shu Shan, et al. "Nematocidal flavone-C-glycosides against the root-knot nematode (Meloidogyne incognita) from Arisaema erubescens tubers." Molecules 16.6 (2011): 5079-5086. | |
Schaftosideextracted from rice phloem can be usedas feeding inhibitors and resistance factors to brown planthoppers,Nilaparvatalugens[1].The screening of several Chinese medicinal herbs for nematicidal properties has shown thatArisaemaerubescens(Wall.) Schott tubers possessed significant nematicidal activity against the root-knot nematode (Meloidogyne incognita). Two nematicidal flavone-C-glycosides were isolated by bioassay-guided fractionation from the ethanol extract. on the basis of their phytochemical and spectral data, the compounds were identified as schaftoside and isoschaftoside. Schaftoside and isoschaftosideexihibited strong nematicidal activity againstM.incognitawith the LC50values of 114.66 μg/mL and 323.09 μg/mL, respectively, the crude extract ofA.erubescensexhibited nematicidal activity against the root-knot nematode with a LC50value of 258.11 μg/mL[2].
References:
[1]. Stevenson P C, Kimmins F M, Grayer R J, et al. Schaftosides from rice phloem as feeding inhibitors and resistance factors to brown planthoppers, Nilaparvatalugens[J]. EntomologiaExperimentalisetApplicata, 1996, 80(1): 246-249.
[2]. Du S S, Zhang H M, Bai C Q, et al. Nematocidal flavone-C-glycosides against the root-knot nematode (Meloidogyne incognita) from Arisaemaerubescens tubers[J]. Molecules, 2011, 16(6): 5079-5086.
| Cas No. | 51938-32-0 | SDF | |
| 别名 | 夏佛塔苷 | ||
| 化学名 | 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]chromen-4-one | ||
| Canonical SMILES | C1C(C(C(C(O1)C2=C(C(=C(C3=C2OC(=CC3=O)C4=CC=C(C=C4)O)O)C5C(C(C(C(O5)CO)O)O)O)O)O)O)O | ||
| 分子式 | C26H28O14 | 分子量 | 564.49 |
| 溶解度 | ≥ 50mg/mL in DMSO, ≥ 50mg/mL in MeOH | 储存条件 | 4°C, protect from light |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.7715 mL | 8.8576 mL | 17.7151 mL |
| 5 mM | 0.3543 mL | 1.7715 mL | 3.543 mL |
| 10 mM | 0.1772 mL | 0.8858 mL | 1.7715 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。