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scIC2

目录号 : GP24887

Single Chain Cardiac Troponin I-C 2nd generation Recombinant

scIC2 Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

Recombinant Single Chain Cardiac Troponin I-C 2nd generation produced in E.Coli is a single, non-glycosylated, polypeptide chain (aa28-110-Linker-cTnC), having a molecular weight of 30kDa.1mg of scIC2 is equivalent to 0.82mg of full length human cardiac TNI on a molar basis.The scIC2 is purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 91.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered colourless liquid formualtion. Shipping Condition Shipped with Ice Packs.
Synonyms Troponin I cardiac muscle; Cardiac troponin I; TNNI3; TNNC1; CMH7; RCM1; cTnI; CMD2A; MGC116817; Troponin C slow skeletal and cardiac muscles; TN-C; TNNC1; TNNC; TNC; CMD1Z.
Stability scIC2 although stable at 10°C for 7 days, should be stored below -18°C . Please prevent freeze-thaw cycles.
Formulation The protein solution contains 20mM Tris-HCl, 250mM NaCl and 50% glycerol, pH 7.5.

Introduction

Troponin Complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, Troponin I, Troponin T and TroponinC. Each subunit is responsible for part of Troponin Complex function. E.g. Troponin I inhibits ATP-ase activity of acto-myosin.Troponin T and Troponin Iare presented in cardiac muscles in different forms than in skeletal muscles. Purified subunits of rcTnI, rcTnC and rcTnT are recomplexed in vitro under appropriate conditions.

Applications

Immunoassays and western blot.

Stability

scIC2 although stable at 10°C for 7 days, should be stored below -18°C . Please prevent freeze-thaw cycles.

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