SEP15 Human
目录号 : GP2452215 KDa Selenoprotein Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | 15 KDa Selenoprotein; SEP15. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSVSAFGAE FSSEACRELG FSSNLLCSSC DLLGQFNLLQ LDPDCRGCCQEEAQFETKKL YAGAILEVCG CKLGRFPQVQ AFVRSDKPKL FRGLQIKYVR GSDPVLKLLD DNGNIAEELSILKWNTDSVE EFLSEKLERI | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | SEP15 protein solution (0.5mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. | ||
15 KDa Selenoprotein (SEP15) is aprotein-coding gene which contains a selenocysteine (Sec) residue at its activesite. The selenocysteineis encoded by the UGA codon that usually signals translation termination. The3' UTR of selenoproteingenes have a conventional stem-loop structure, the sec insertion sequence(SECIS), which is necessaryfor the recognition of UGA as a Sec codon rather than as a stop signal. Studiesin mouse propose that thisselenoprotein may have redox function and may be implicated in the qualitycontrol of protein folding. This gene is localized on chromosome 1p31, a genetic locus usuallymutated or deleted in human cancers.Diseases associated with SEP15 include lung cancer susceptibility, andchronic lymphocytic leukemia.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.