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SEPW1 Human

目录号 : GP24526

Selenoprotein W 1 Human Recombinant

SEPW1 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥67,200.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

SEPW1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 110 amino acids (1-87 a.a) andhaving a molecular mass of 11.8kDa.SEPW1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms Selenoprotein W; 1; SelW; Selenoprotein W.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMALAVRV VYCGACGYKS KYLQLKKKLE DEFPGRLDIC GEGTPQATGFFEVMVAGKLI HSKKKGDGYV DTESKFLKLV AAIKAALAQG.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation SEPW1 protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.

Introduction

Selenoprotein W 1, also known as SEPW1 is a selenoprotein, which has aselenocysteine (Sec) residue at its active site. The selenocysteine is encodedthrough the UGA codon which normally signals translation termination. The 3'UTR of selenoprotein genes share a common stem-loop structure, the secinsertion sequence (SECIS), which is essential for the recognition of UGA as aSec codon instead of as a stop signal. SEPW1 shows highest expression inskeletal muscle and heart, and also involved in oxidation-reduction reactions.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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