sIL 6R Human
目录号 : GP20525Interleukin-6 Soluble Receptor Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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sIL-6R Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 338 amino acids (20-357) corresponding to the mature IL-6R protein, having a molecular weight of 42.25 kDa, with an aminoterminal hexahistidine tag.The sIL6R is purified by proprietary chromatographic techniques.
| Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | IL6R-alpha; CD126; IL-6R 1; CD126 antigen; IL6RA; Interleukin 6 receptor; Interleukin 6 receptor alpha subunit; Interleukin-6 receptor alpha chain precursor; B cell stimulatory factor-2;Membrane glycoprotein 80; gp80; IL-6R; MGC104991. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. | ||
| Formulation | CD126 His-Tag protein is supplied in 20mM Tris-HCl, pH 8.0, 0.8M Urea & 50% glycerol. | ||
The IL-6 receptor complex is composed of two membrane glycoproteins: the low affinity receptor and the signaltransducing component. The soluble form of IL6R is found in the urine of healthy adult humans and the serum of HIV positive individuals, as well as in the cell culture supernatants of stimulated PBMCбпs. This soluble form of IL6R results from either proteolytic cleavage from the membrane, or an isoform derived splice variant.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.