Sincalide
目录号 : GP21306Sincalide (Cholecystokinin octapeptide, CCK-8) 是一种快速作用的胆囊收缩素 (CCK) 氨基酸多肽激素类似物，可用于静脉输液后胆囊造影。
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 99.0% as determined by RP-HPLC. | Source | |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Solubility | It is recommended to reconstitute the lyophilized Sincalide in sterile 18MΩ-cm H2O at a concentration of 0.5mg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized Sincalide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution CCK-8 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
| Formulation | The Sincalide was lyophilized from a concentrated (1mg/ml) solution with no additives. | ||
Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) which acts on receptors within the gallbladder wall causing it to contract.Cholecystokinin (CCK) is a hormone originally isolated from porcine intestinal mucosa and described as a linear 33-amino acid peptide containing a sulfated tyrosine, which is essential for its biological activity. It has been found in mammals in both the digestive tract and the central nervous system. Among its multiple biological functions, this hormone stimulates pancreatic exocrine secretion, gallbladder contraction, and intestine motility and may also act as a neurotransmitter/neuromodulator in the central nervous system.
Lyophilized Sincalide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution CCK-8 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.