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Sodium Houttuyfonate Sale

(Synonyms: 鱼腥草素纳) 目录号 : GC39128

Sodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.

Sodium Houttuyfonate Chemical Structure

Cas No.:83766-73-8

规格 价格 库存 购买数量
5mg
¥450.00
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10mg
¥720.00
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20mg
¥1,260.00
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Sample solution is provided at 25 µL, 10mM.

Description

Sodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.

Treatment with sodium houttuyfonate results in an increase in the expression of c-Fos protein in macrophages, while the phosphorylation level of extracellular signal-related kinase 1/2 (ERK1/2) is not affected by the treatment[2].

Sodium houttuyfonate has been shown to protect against cationized bovine serum albumin (C-BSA)-induced glomerulonephritis in BALB/C mice through the suppression of the urine protein, morphological character and monocyte chemotactic protein 1 (MCP-1). In addition, sodium houttuyfonate treatment has been shown to induce a respiratory burst and to increase the concentration of free calcium in macrophages, as well as increase IL-2 within T-cells. Sodium houttuyfonate in the serum, stomach and intestine can be detected immediately by GC at 0.5 h. The concentration of sodium houttuyfonate in the stomach gradually increases from 0.5–2 h, but is drastically reduced at 4 h. Furthermore, the concentration in the serum and intestine at 1–4 h decreases in a time-dependent manner, indicating that sodium houttuyfonate can be quickly absorbed into the circulatory system and intestine and might be quickly distributed to other organs, such as trachea, lung, brain, heart and kidney[2].

[1] JUN LI, et al. Exp Ther Med. 2014, 7(6): 1639–1642. [2] Chen J, et al. Int J Mol Sci. 2014, 15(12):22978-94.

化学性质

Cas No. 83766-73-8 SDF
别名 鱼腥草素纳
Canonical SMILES O=S(C(O)CC(CCCCCCCCC)=O)(O[Na])=O
分子式 C12H23NaO5S 分子量 302.36
溶解度 DMSO: 5 mg/mL (16.54 mM; ultrasonic and warming and heat to 60°C) 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.3073 mL 16.5366 mL 33.0732 mL
5 mM 0.6615 mL 3.3073 mL 6.6146 mL
10 mM 0.3307 mL 1.6537 mL 3.3073 mL
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