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Sophoraflavanone G Sale

(Synonyms: 槐黄烷酮G,Kushenol F) 目录号 : GC38970

A flavonoid with diverse biological activities

Sophoraflavanone G Chemical Structure

Cas No.:97938-30-2

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5mg
¥1,071.00
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10mg
¥1,818.00
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20mg
¥3,087.00
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Sample solution is provided at 25 µL, 10mM.

Description

Sophoraflavanone G is a flavonoid that has been found in S. flavescens and has diverse biological activities.1,2,3,4 It is active against 21 strains of methicillin-resistant S. aureus (MRSA; MICs = 3.13-6.25 ?g/ml) and inhibits the activities of α-glucosidase and β-amylase (Kis = 5.6 and 30.6 ?M, respectively).1,2 Sophoraflavanone G is cytotoxic to HL-60 and HepG2 cancer cells (IC50s = 12.5 and 13.3 ?M, respectively) and induces apoptosis in HL-60 cells when used at concentrations of 10 or 25 ?M.3 It reduces LPS-induced production of prostaglandin E2 in RAW 264.7 cells when used at concentrations ranging from 1 to 50 ?M.4 Sophoraflavanone G (250 mg/kg) inhibits carrageenan-induced paw edema in rats.

1.Sato, M., Tsuchiya, H., Takase, I., et al.Antibacterial activity of flavanone isolated from Sophora exigua against methicillin-resistant Staphylococcus aureus and its combination with antibioticsPhytother. Res.9(7)509-512(1995) 2.Kim, J.H., Ryu, Y.B., Kang, N.S., et al.Glycosidase inhibitory flavonoids from Sophora flavescensBiol. Pharm. Bull.29(2)302-305(2006) 3.Ko, W.G., Kang, T.H., Kim, N.Y., et al.Lavandulylfavonoids: A new class of in vitro apoptogenic agents from Sophora favescensToxicol. In Vitro14(5)429-433(2000) 4.Kim, D.W., Chi, Y.S., Son, K.H., et al.Effects of sophoraflavanone G, a prenylated flavonoid from Sophora flavescens, on cyclooxygenase-2 and in vivo inflammatory responseArch. Pharm. Res.25(3)329-335(2002)

化学性质

Cas No. 97938-30-2 SDF
别名 槐黄烷酮G,Kushenol F
Canonical SMILES O=C1C[C@@H](C2=CC=C(O)C=C2O)OC3=C(C[C@H](C(C)=C)C/C=C(C)\C)C(O)=CC(O)=C13
分子式 C25H28O6 分子量 424.49
溶解度 DMSO: 250 mg/mL (588.94 mM) 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

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1 mg 5 mg 10 mg
1 mM 2.3558 mL 11.7788 mL 23.5577 mL
5 mM 0.4712 mL 2.3558 mL 4.7115 mL
10 mM 0.2356 mL 1.1779 mL 2.3558 mL
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