Staphylokinase
目录号 : GP22263Staphylokinase Recombinant
Sample solution is provided at 25 µL, 10mM.
Staphylokinase Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 136 amino acids and having a molecular weight of16kDa.The Staphylokinase is purified by proprietary chromatographic techniques.
Purity | Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
Synonyms | Staphylokinase; SakSTAR; Neutral proteinase; Protease III; SAK. | ||
Solubility | It is recommended to reconstitute the lyophilized SAKin sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
Stability | Lyophilized SAK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution SAK should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles. | ||
Biological Activity | The biological activity measured by the ability of fibrin lysis in agarose plate was found to be 50,000IU/mg. | ||
Formulation | Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4. |
Staphylokinase (SAK) is a 136-amino acidenzymefrom Staphylococcus aureus. It is positively regulated by the "agr" gene regulator. It activates plasminogen, which in turn can degrade various host proteins during infection.
The biological activity measured by the ability of fibrin lysis in agarose plate was found to be 50,000IU/mg.
Lyophilized SAK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution SAK should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.