STIP1 Human
目录号 : GP24720Stress-Induced-Phosphoprotein 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 95.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Stress Induced Phosphoprotein 1; Transformation-SensitiveProtein IEF SSP 3521; Renal Carcinoma Antigen NY-REN-11;Stress-Induced-Phosphoprotein 1; Hsp70/Hsp90-Organizing Protein;Hsc70/Hsp90-Organizing Protein; STI1; HOP; Epididymis Secretory Sperm BindingProtein Li 94n; NY-REN-11 Antigen; IEF-SSP-3521; HEL-S-94n; STI1L; P60. | ||
| Amino Acid Sequence | MEQVNELKEK GNKALSVGNI DDALQCYSEA IKLDPHNHVL YSNRSAAYAKKGDYQKAYED GCKTVDLKPD WGKGYSRKAA ALEFLNRFEE AKRTYEEGLK HEANNPQLKE GLQNMEARLAERKFMNPFNM PNLYQKLESD PRTRTLLSDP TYRELIEQLR NKPSDLGTKL QDPRIMTTLS VLLGVDLGSMDEEEEIATPP PPPPPKKETK PEPMEEDLPE NKKQALKEKE LGNDAYKKKD FDTALKHYDK AKELDPTNMTYITNQAAVYF EKGDYNKCRE LCEKAIEVGR ENREDYRQIA KAYARIGNSY FKEEKYKDAI HFYNKSLAEHRTPDVLKKCQ QAEKILKEQE RLAYINPDLA LEEKNKGNEC FQKGDYPQAM KHYTEAIKRN PKDAKLYSNRAACYTKLLEF QLALKDCEEC IQLEPTFIKG YTRKAAALEA MKDYTKAMDV YQKALDLDSS CKEAADGYQRCMMAQYNRHD SPEDVKRRAM ADPEVQQIMS DPAMRLILEQ MQKDPQALSE HLKNPVIAQK IQKLMDVGLI AIR. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrierprotein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | STIP1 protein solution (0.5mg/ml) containing 20mMTris-HCl (pH 8.0), 10% glycerol, 1mM DTT and 0.1M NaCl. | ||
STIP1 is an adaptor protein that mediates the functions of HSP70 & HSP90 in protein folding. STIP1 supports the transfer of proteins from HSP70 to HSP90 by binding together HSP90 and substrate-bound HSP70. STIP1 stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones. STIP1 genetic variations are involved in regulating corticosteroid response in asthmatic subjects with reduced lung function.
Store at 4°C if entire vial will be used within 2-4weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrierprotein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.