Sunset Yellow FCF (Food Yellow 3)
(Synonyms: 日落黄,Orange Yellow S; Food Yellow 3; CI 15985) 目录号 : GC30246
An azo dye
Cas No.:2783-94-0
Sample solution is provided at 25 µL, 10mM.
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Sunset yellow FCF is an azo dye.1 It displays an absorption maximum of 480 nm.1,2 It reduces LPS-induced proliferation of isolated mouse splenocytes, as well as inhibits proliferation of isolated mouse splenocytes in an allogenic mixed lymphocyte reaction when used at a concentration of 250 ?g/ml.3 Sunset yellow FCF (0.325 mg/kg) induces chromosomal aberrations in somatic and germ cells and morphological abnormalities in sperm in mice, but it is not genotoxic in a micronucleus gut assay in mice when administered at doses up to 2,000 mg/kg.4 Formulations containing sunset yellow FCF have been used as colorants in food and cosmetic preparations.
1.Ghoneim, M.M., El-Desoky, H.S., and Zidan, N.M.Electro-Fenton oxidation of Sunset Yellow FCF azo-dye in aqueous solutionsDesalination274(1-3)22-30(2011) 2.Sabnis, R.W.Handbook of biological dyes and stains: Synthesis and industrial applications(2010) 3.Yadav, A., Kumar, A., Tripathi, A., et al.Sunset yellow FCF, a permitted food dye, alters functional responses of splenocytes at non-cytotoxic doseToxicol. Lett.217(3)197-204(2013) 4.Sayed, H.M., Fouad, D., Ataya, F.S., et al.The modifying effect of selenium and vitamins A, C, and E on the genotoxicity induced by sunset yellow in male miceMutat. Res.744(2)145-153(2012)
| Cas No. | 2783-94-0 | SDF | |
| 别名 | 日落黄,Orange Yellow S; Food Yellow 3; CI 15985 | ||
| Canonical SMILES | O=S(C1=CC=C2C(/N=N/C3=CC=C(S(=O)([O-])=O)C=C3)=C(O)C=CC2=C1)([O-])=O.[Na+].[Na+] | ||
| 分子式 | C16H10N2Na2O7S2 | 分子量 | 452.37 |
| 溶解度 | Water : ≥ 100 mg/mL (221.06 mM) | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 2.2106 mL | 11.0529 mL | 22.1058 mL |
| 5 mM | 0.4421 mL | 2.2106 mL | 4.4212 mL |
| 10 mM | 0.2211 mL | 1.1053 mL | 2.2106 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
- Purity: >99.50%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet